Patents by Inventor Nadim Jessani

Nadim Jessani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Proteomic analysis
    Patent number: 7348437
    Abstract: Activity-based compositions for analyzing metalloproteases are disclosed, where the compositions include a chemical compound including a hydroxamate moiety and a benzophenone moiety. Methods for synthesizing these compounds are also disclosed, as well as methods of using them for determining the bioactivity of a compositions comprising active compounds toward a metalloproteases and for determining the potency of an inhibitor against a metalloprotease.
    Type: Grant
    Filed: June 1, 2005
    Date of Patent: March 25, 2008
    Assignee: The Scripps Research Institute
    Inventors: Benjamin F. Cravatt, Alan Saghatelian, Nadim Jessani, Arul Joseph
  • Proteomic analysis
    Publication number: 20050266505
    Abstract: Activity-based compositions for analyzing metalloproteases are disclosed, where the compositions include a chemical compound including a hydroxamate moiety and a benzophenone moiety. Methods for synthesizing these compounds are also disclosed, as well as methods of using them for determining the bioactivity of a compositions comprising active compounds toward a metalloproteases and for determining the potency of an inhibitor against a metalloprotease.
    Type: Application
    Filed: June 1, 2005
    Publication date: December 1, 2005
    Applicant: THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Benjamin Cravatt, Alan Saghatelian, Nadim Jessani, Arul Joseph
  • Enzyme activity profiles
    Publication number: 20030143648
    Abstract: Methods and compositions are provided for evaluating cellular status related to neoplasia. Affinity based probes, particularly having fluorophosphonates as a reactive functionality, are employed that react with a family of enzymes having a common catalytic activity, particularly serine/threonine hydrolases. The probe(s) are combined with the cell components and resulting conjugates are characterized, where the profile of reaction indicates cellular status. A novel serine/threonine hydrolase enzyme is provided.
    Type: Application
    Filed: November 25, 2002
    Publication date: July 31, 2003
    Inventors: Benjamin F. Cravatt, Nadim Jessani, Yongsheng Liu