Patents by Inventor Nadine FRANCOIS

Nadine FRANCOIS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vitro diagnostic method for an invasive fungal infection using MALDI-TOFF mass spectrometry
    Patent number: 9360470
    Abstract: A method for the in vitro diagnosis of an invasive fungal infection by MALDI-TOF mass spectrometry. The method involves, providing a liquid biological sample from a mammal, said biological sample containing, in particular, proteins and/or lipids and/or salts and/or polysaccharides and/or oligosaccharides and/or monosaccharides capable of forming complexes with said proteins and/or lipids and/or salts; treating said sample with biological liquid so as to extract said polysaccharides and/or oligosaccharides and/or monosaccharides; determining, by MALDI-TOF mass spectrometry, whether or not there is present among said extracted polysaccharides, oligosaccharides and/or monosaccharides, at least one given compound of interest coming from said fungal microorganism and chosen from polysaccharides, oligosaccharides and monosaccharides; and deducing, if said given compound of interest is present in said sample, that said mammal is suffering from an invasive fungal infection.
    Type: Grant
    Filed: June 24, 2013
    Date of Patent: June 7, 2016
    Assignees: Centre Hospitalier Regional Universitaire De Lille, Universite De Droit Et Sante De Lille, Universite Sciences Technologies Lille, Centre National De La Recherche Scientifique
    Inventors: Daniel Poulain, Boualem Sendid, Yann Guerardel, Nadine Francois
  • IN VITRO DIAGNOSTIC METHOD FOR AN INVASIVE FUNGAL INFECTION USING MALDI-TOFF MASS SPECTROMETRY
    Publication number: 20150338391
    Abstract: A method for the in vitro diagnosis of an invasive fungal infection by MALDI-TOF mass spectrometry. The method involves, providing a liquid biological sample from a mammal, said biological sample containing, in particular, proteins and/or lipids and/or salts and/or polysaccharides and/or oligosaccharides and/or monosaccharides capable of forming complexes with said proteins and/or lipids and/or salts; treating said sample with biological liquid so as to extract said polysaccharides and/or oligosaccharides and/or monosaccharides; determining, by MALDI-TOF mass spectrometry, whether or not there is present among said extracted polysaccharides, oligosaccharides and/or monosaccharides, at least one given compound of interest coming from said fungal microorganism and chosen from polysaccharides, oligosaccharides and monosaccharides; and deducing, if said given compound of interest is present in said sample, that said mammal is suffering from an invasive fungal infection.
    Type: Application
    Filed: June 24, 2013
    Publication date: November 26, 2015
    Inventors: Daniel POULAIN, Boualem SENDID, Yann GUERARDEL, Nadine FRANCOIS