Patents by Inventor Naduparambil Jacob

Naduparambil Jacob has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10513736
    Abstract: Disclosed herein are compositions and methods for monitoring hematopoietic reconstitution or suppression in a subject. Also disclosed are compositions and methods for reconstituting the hematopoietic compartment of a subject in need thereof. Also disclosed is a method for monitoring the effect of ionizing radiation on the lung in a subject. Also disclosed is the ability to use detection of the one or more microRNA indicative of radiation-induced lung injury to guide therapy of the subject. Also disclosed is the ability to use detection of the one or more microRNA indicative of radiation-induced lung injury to evaluate the efficacy of a lung treatment following radiation exposure.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: December 24, 2019
    Assignee: Ohio State Innovation Foundation
    Inventors: Naduparambil Jacob, Arnab Chakravarti
  • Patent number: 10407726
    Abstract: Disclosed herein are miRNA biomarkers and methods for measuring exposure of a mammalian subject to ionizing radiation using a cell-free biological sample. Also disclosed are dosimeters and methods for triaging and treating a subject exposed to ionizing radiation.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: September 10, 2019
    Assignee: Ohio State Innovation Foundation
    Inventors: Naduparambil Jacob, Arnab Chakravarti
  • Publication number: 20190177795
    Abstract: Disclosed herein are compositions and methods for monitoring hematopoietic reconstitution or suppression in a subject. Also disclosed are compositions and methods for reconstituting the hematopoietic compartment of a subject in need thereof. Also disclosed is a method for monitoring the effect of ionizing radiation on the lung in a subject. Also disclosed is the ability to use detection of the one or more microRNA indicative of radiation-induced lung injury to guide therapy of the subject. Also disclosed is the ability to use detection of the one or more microRNA indicative of radiation-induced lung injury to evaluate the efficacy of a lung treatment following radiation exposure.
    Type: Application
    Filed: November 19, 2018
    Publication date: June 13, 2019
    Inventors: Naduparambil Jacob, Arnab Chakravarti
  • Patent number: 10131952
    Abstract: Disclosed herein are compositions and methods for monitoring hematopoietic reconstitution or suppression in a subject. Also disclosed are compositions and methods for reconstituting the hematopoietic compartment of a subject in need thereof. Also disclosed is a method for monitoring the effect of ionizing radiation on the lung in a subject. Also disclosed is the ability to use detection of the one or more microRNA indicative of radiation-induced lung injury to guide therapy of the subject. Also disclosed is the ability to use detection of the one or more microRNA indicative of radiation-induced lung injury to evaluate the efficacy of a lung treatment following radiation exposure.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: November 20, 2018
    Assignee: Ohio State Innovation Foundation
    Inventors: Naduparambil Jacob, Arnab Chakravarti
  • Publication number: 20180195127
    Abstract: Disclosed herein are miRNA biomarkers and methods for measuring exposure of a mammalian subject to ionizing radiation using a cell-free biological sample. Also disclosed are dosimeters and methods for triaging and treating a subject exposed to ionizing radiation.
    Type: Application
    Filed: December 19, 2017
    Publication date: July 12, 2018
    Inventors: Naduparambil JACOB, Arnab CHAKRAVARTI
  • Patent number: 9890428
    Abstract: Disclosed herein are miRNA biomarkers and methods for measuring exposure of a mammalian subject to ionizing radiation using a cell-free biological sample. Also disclosed are dosimeters and methods for triaging and treating a subject exposed to ionizing radiation.
    Type: Grant
    Filed: May 14, 2014
    Date of Patent: February 13, 2018
    Assignee: Ohio State Innovation Foundation
    Inventors: Naduparambil Jacob, Arnab Chakravarti
  • Publication number: 20170101681
    Abstract: Disclosed herein are compositions and methods for monitoring hematopoietic reconstitution or suppression in a subject. Also disclosed are compositions and methods for reconstituting the hematopoietic compartment of a subject in need thereof. Also disclosed is a method for monitoring the effect of ionizing radiation on the lung in a subject. Also disclosed is the ability to use detection of the one or more microRNA indicative of radiation-induced lung injury to guide therapy of the subject. Also disclosed is the ability to use detection of the one or more microRNA indicative of radiation-induced lung injury to evaluate the efficacy of a lung treatment following radiation exposure.
    Type: Application
    Filed: May 14, 2015
    Publication date: April 13, 2017
    Inventors: Naduparambil JACOB, Arnab CHAKRAVARTI
  • Publication number: 20140341841
    Abstract: Disclosed herein are miRNA biomarkers and methods for measuring exposure of a mammalian subject to ionizing radiation using a cell-free biological sample. Also disclosed are dosimeters and methods for triaging and treating a subject exposed to ionizing radiation.
    Type: Application
    Filed: May 14, 2014
    Publication date: November 20, 2014
    Applicant: The Ohio State Innovation Foundation
    Inventors: Naduparambil Jacob, Arnab Chakravarti