Abstract: The present application relates to an amphiphilic triblock polymer and micelles comprising the amphiphilic triblock polymer. The amphiphilic triblock polymer of the present application can have excellent dispersion properties and excellent water solubility while effectively encapsulating the drug.

Abstract: The present disclosure relates to an apparatus and a process which can continuously produce microneedles using a conveyor system and decomposition or vacuum. By using the microneedle production method and apparatus according to the present disclosure, continuous mass production of microneedles is available, and therefore it is possible to reduce the input of manpower and produce a large amount of products compared to the conventional production method.

Abstract: The present invention relates to a system for administering a poorly-soluble compound to the skin, the system being capable of exerting an excellent effect by stably impregnating the poorly-soluble compound and effectively delivering the poorly-soluble compound into the skin, and the present invention is technically characterized by a microneedle to which microparticles comprising a poorly-soluble compound are added. In addition, the present invention provides a method for administering a poorly-soluble compound to the skin, the method being characterized by using the microneedle.

Abstract: The present disclosure relates to a composition for improving optical characteristics of skin, which improves changes of optical characteristics of skin and skin texture, changes of skin tone such as dullness, and the like, caused by progress of keratinization, by applying an optical clearing agent to skin, and thereby, it comprises an optical clearing agent in the composition, thereby having an effect of reducing crystallization of constituents as the optical clearing agent penetrates between keratinocytes, and reducing light scattering as the substance for improving optical characteristics penetrated in the keratinocytes remains in the keratinocytes and binds to water, and through this, improving skin clearing, skin tone and skin texture, and therefore, it may be very usefully used as skin external preparation and cosmetic compositions.

Abstract: The present application relates to an amphiphilic polymer and a method of preparing the same. Furthermore, the present application relates to a micelle including a drug encapsulated by the amphiphilic polymer and a composition including the same. The amphiphilic polymer according to the present application has excellent drug encapsulation properties as well as good dispersion properties in an aqueous solution.

Abstract: The present invention provides a composition for treating hair, skin, or fiber, comprising a cationic cellulose polymer. In the present invention, the cationic cellulose polymer may be used for various purposes by adjusting the molecular weight. Specifically, the present invention provides the use of the cationic cellulose polymer for imparting flexibility to hair, skin, or fiber, the use for cumulatively adsorbing active ingredients onto hair, skin, or fiber by allowing the active ingredients to be bound to the cationic cellulose polymer, the use for transferring active ingredients to hair, skin, or fiber by allowing the active ingredients to be bound to the cationic cellulose polymer, and the use of the cationic cellulose polymer, a crosslinking-mediating component having a carboxyl group or amine group, and a carbodiimide-based compound for preventing the loss of hair, skin, or fiber components.

Abstract: The present application relates to an amphiphilic polymer and a method for producing the same. The present application also relates to micelles comprising the amphiphilic polymer and a method for producing the same. The amphiphilic polymer of the present application can have excellent dispersion properties while effectively encapsulating the drug.

Abstract: The present disclosure relates to a method for manufacturing a microneedle containing a coating part on a needle tip and an apparatus used for the method. When a microneedle is manufactured using the coating method and apparatus according to the present disclosure, a coating part in which a target material is impregnated can be easily inserted into skin and effective dissolution is possible. Further, the target material is allowed to show excellent skin permeability with the dissolution of the coating part of the microneedle manufactured according to the present disclosure, thereby a quantitative amount of target material can be effectively delivered into the skin.

Abstract: The present application relates to an amphiphilic triblock polymer and micelles comprising the amphiphilic triblock polymer. The amphiphilic triblock polymer of the present application can have excellent dispersion properties and excellent water solubility while effectively encapsulating the drug.

Abstract: The present disclosure relates to a cosmetic composition for blocking fine dust. The composition according to the present disclosure can fundamentally prevent problems due to fine dust by reducing the attachment rate of fine dust attached to skin.

Abstract: The present disclosure relates to a soluble microneedle and a filler composition with an excellent anti-wrinkle effect. Using the microneedle according to the present disclosure, crosslinked hyaluronic acid (hyaluronic acid filler material) can be intradermally or subcutaneously administered by a simple method, and a swelling property of the crosslinked hyaluronic acid is improved after administration, thereby exhibiting the excellent anti-wrinkle effect.

Abstract: A skin administration system capable of ensuring the stability of peptides or proteins and enhancing the delivery rate of peptides or proteins through the skin and, more particularly, microneedles including peptides or proteins are provided. Microneedles including a protein or peptide are also provided, in particular microneedles including a microparticle including a peptide or a protein, in particular wherein the peptide or the protein is stably entrapped inside the microparticle, more particularly without aggregation. The material forming the microneedle can be soluble in the skin and the protein or the peptide can be stably delivered into the skin as the microneedle is dissolved or disintegrated when the microneedle is applied to the skin.

Abstract: Provided is a cosmetic composition for improving skin conditions including a fusion protein containing a skin penetration enhancing peptide, more particularly, a fusion protein in which PDGFa is bound to the skin penetration enhancing peptide, and a cosmetic composition for improving skin conditions, a functional cosmetic product for improving skin conditions, a cosmetic composition for preventing and treating alopecia, and a quasi-drug composition each including the fusion protein.

Abstract: The present invention relates to a skin administration system capable of improving the efficiency of skin delivery of an ingredient for controlling release of neurotransmitters and, particularly, to a microneedle containing an ingredient for controlling release of neurotransmitters.

Abstract: The present invention relates to a skin administration system capable of improving the efficiency of skin delivery of an ingredient for controlling release of neurotransmitters and, particularly, to a microneedle containing an ingredient for controlling release of neurotransmitters.

Abstract: The present application relates to an amphiphilic polymer and a method of preparing the same. Furthermore, the present application relates to a micelle including a drug encapsulated by the amphiphilic polymer and a composition including the same. The amphiphilic polymer according to the present application has excellent drug encapsulation properties as well as good dispersion properties in an aqueous solution.

Abstract: The present application relates to an amphiphilic polymer and a method of preparing the same. Furthermore, the present application relates to a micelle including a drug encapsulated by the amphiphilic polymer and a composition including the same. The amphiphilic polymer according to the present application has excellent drug encapsulation properties as well as good dispersion properties in an aqueous solution.

Abstract: The present invention relates to a soluble microneedle and, more particularly, to a microneedle and a microneedle patch comprising the same, wherein the microneedle is used to perforate skin, and the microneedle, when inserted through the perforated skin, is then dissolved, thereby administering the target material from inside the microneedle into the skin. The microneedle according to the present invention, when used, has appropriate levels of mechanical strength, viscosity, and hardness and can be easily inserted into skin without undergoing shape change, for example, bending or breaking, thereby enabling efficient skin perforation. In addition, as the microneedle according to the present invention is dissolved through the perforated skin, the target material penetrates the skin at an excellent ratio. Accordingly, there is no need to apply strong force, and the target material can be effectively delivered into the skin regardless of which part of the microneedle contains the target material.

Abstract: The present application relates to an amphiphilic polymer and a method of preparing the same. Furthermore, the present application relates to a micelle including a drug encapsulated by the amphiphilic polymer and a composition including the same. The amphiphilic polymer according to the present application has excellent drug encapsulation properties as well as good dispersion properties in an aqueous solution.

Abstract: The present disclosure relates to a networked dispersion of biocellulose microfibrils in water wherein the biocellulose microfibrils have carboxylic groups substituted for alcohol groups, are 30-60 nm in number average diameter with a maximum diameter of 60-100 nm, and are dispersed in an aqueous phase while forming a network. The networked dispersion of biocellulose microfibrils in water according to the present disclosure exhibits excellent skin compatibility and has the effect of allowing the skin to increase in water absorption, elasticity and smoothness. In addition, not only does the networked dispersion of biocellulose microfibrils in water form micro-networks on the skin to prevent microdust from being brought into direct contact with the skin, but also negative charges of the networked dispersion repel those microdust to reduce microdust attachment, so that the present disclosure can be widely utilized in developing a variety of compositions for effectively blocking microdust.