Abstract: There is disclosed a method of preparing a photographic solid fine-grain dispersion, the method comprising the steps of: successively bringing a slurry of a water-insoluble photographically useful compound in a grinding chamber of a dispersing machine, which chamber is filled with media, allowing the compound to contact the media in the grinding chamber, to produce fine grains of the compound successively, successively separating the media from the compound by centrifugal force, and taking the compound out of the grinding chamber, using specific media with given physical properties. There is also disclosed a dispersion obtained by the method. According to the method, the photographic solid fine-grain dispersion is prepared efficiently, without coarse grains or abrasion materials resulting from media or so, and the dispersion causes no defect when coated in a form of a coating film.

Abstract: A prolonged release dosage form of drug made by coating a surface of an ungranulated medicinal particle with a water-insoluble material which is physiologically acceptable and does not dissolve in water and gastric juice; and then, granulating or tableting the coated medicinal particles.

Abstract: A coating apparatus using jet air streams, wherein a spray nozzle (2) of the coating apparatus includes: a powder blow-out path (4) provided in an axially central portion of the main body (3) of the nozzle; a coating liquid blow-out path (5) annularly formed on the outer periphery of the powder blow-out path (4); and a compressed air blow-out path (6) having a taper-shaped outlet portion and annularly formed on the outer periphery of the coating liquid blow-out path (5).

Abstract: A method of performing granulating, coating, drying of a powdry or granular material having a relatively minute particle diameter and an apparatus therefor. A nozzle for supplying the powdery or granular material and a nozzle for supplying a coating liquid are parallelly provided at adjacent positions where air streams dispersed from the both nozzles are not in contact with each other and directed to the interior of a processing cylinder. The two nozzles are connected to compressed air sources independently of each other. Drying air-stream blow-in openings are provided on the way from collision of the powdery or granular material and the coating material to catching thereof. Drying air streams are supplied from a direction tangent to the processing cylinder having a circular section.

Abstract: A granulating and coating method using the drying air streams to effectuate granulating, coating and drying and apparatus therefore wherein:a nozzle for supplying an article to be coated and another nozzle for supplying a coating material are provided at such positions that the article to be coated and the coating material collide with each other before the article to be coated and the coating material are dispersed by the drying air streams.

Abstract: A granulating and coating apparatus in which a rotary drum containing powdery or granular material is rotated about the substantially horizontal axis for granulating and/or coating the powdery or granular material. The apparatus is provided with a disk valve mechanism for switching a gas supply or exhaust path to the rotary drum on the operating side of the rotary drum. The rotary drum is provided inside of itself with a baffle means for stirring powdery or granular material and a baffle displacing means for displacing the baffle means. Inside of the rotary drum is provided a temperature sensor for directly measuring a temperature of powdery or granular material. The rotary drum is composed of porous polygonal. Each side of the polygonal drum includes an outer enclosure mounted thereon and individual detachable.

Abstract: A granulating and coating apparatus comprising a rotary drum to be charged therein a powdery or granular material, and a baffle plate provided in the rotary drum and not rotatable together with the rotary drum. The rotary drum is formed to be a polygonal shape. This polygonal shape may be, for example, a pentagon, a hexagon, an octagon or a decagon. The baffle plate may be positionally fixedly supported. Or, the baffle plate can be made to change a position in a rocking direction, a position of the rotary drum in the axial direction, a depth of insertion into a layer of a powdery or granular material or an angle of insertion by use of plurality of actuators.