Patents by Inventor Nagamani Datla

Nagamani Datla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10035989
    Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in the seed of transgenic plants by introducing, into the organism, nucleic acids which encode polypeptides with a ?3-desaturase, ?12-desaturase, ?6-desaturase, ?6-elongase, ?5-desaturase, ?5-elongase and/or ?4-desaturase activity. The invention furthermore relates to recombinant nucleic acid molecules comprising the nucleic acid sequences which encode the aforementioned polypeptides, either jointly or individually, and transgenic plants which comprise the aforementioned recombinant nucleic acid molecules. Furthermore, the invention relates to the generation of a transgenic plant and to oils, lipids and/or fatty acids with an elevated content of polyunsaturated fatty acids, in particular arachidonic acid, eicosapentaenoic acid and/or docosahexaenoic acid, as the result of the expression of the elongases and desaturases used in the process according to the invention.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: July 31, 2018
    Assignee: BASF Plant Science GmbH
    Inventors: Petra Cirpus, Jörg Bauer, Xiao Qiu, Guohai Wu, Nagamani Datla
  • Patent number: 9458436
    Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in the seed of transgenic plants by introducing, into the organism, nucleic acids which encode polypeptides with a ?3-desaturase, ?12-desaturase, ?6-desaturase, ?6-elongase, ?5-desaturase, ?5-elongase and/or ?4-desaturase activity. The invention furthermore relates to recombinant nucleic acid molecules comprising the nucleic acid sequences which encode the aforementioned polypeptides, either jointly or individually, and transgenic plants which comprise the aforementioned recombinant nucleic acid molecules. Furthermore, the invention relates to the generation of a transgenic plant and to oils, lipids and/or fatty acids with an elevated content of polyunsaturated fatty acids, in particular arachidonic acid, eicosapentaenoic acid and/or docosahexaenoic acid, as the result of the expression of the elongases and desaturases used in the process according to the invention.
    Type: Grant
    Filed: February 23, 2005
    Date of Patent: October 4, 2016
    Assignee: BASF Plant Science GmbH
    Inventors: Petra Cirpus, Jörg Bauer, Xiao Qiu, Guohai Wu, Nagamani Datla
  • Publication number: 20150361404
    Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in the seed of transgenic plants by introducing, into the organism, nucleic acids which encode polypeptides with a ?3-desaturase, ?12-desaturase, ?6-desaturase, ?6-elongase, ?5-desaturase, ?5-elongase and/or ?4-desaturase activity. The invention furthermore relates to recombinant nucleic acid molecules comprising the nucleic acid sequences which encode the aforementioned polypeptides, either jointly or individually, and transgenic plants which comprise the aforementioned recombinant nucleic acid molecules. Furthermore, the invention relates to the generation of a transgenic plant and to oils, lipids and/or fatty acids with an elevated content of polyunsaturated fatty acids, in particular arachidonic acid, eicosapentaenoic acid and/or docosahexaenoic acid, as the result of the expression of the elongases and desaturases used in the process according to the invention.
    Type: Application
    Filed: August 11, 2015
    Publication date: December 17, 2015
    Inventors: Petra Cirpus, Jörg Bauer, Xiao Qiu, Guohai Wu, Nagamani Datla
  • Patent number: 8134046
    Abstract: The present invention relates to a process for producing arachidonic acid and/or eicosapentaenoic acid in transgenic useful plants by introducing into the plant nucleic acids coding for polypeptides having ?6-desaturase, ?6-elongase or ?5-desaturase activity. Furthermore, a gene coding for an ?3-desaturase is advantageously expressed in said useful plants. In another advantageous embodiment of the process, further nucleic acid sequences coding for polypeptides of fatty acid or lipid metabolism biosynthesis may be expressed in the plants. Particularly advantageous nucleic acid sequences here are those coding for a ?8-desaturase, ?12-desaturase, ?15-desaturase, ?4-desaturase, ?9-elongase and/or ?5-elongase activity. The invention further relates to the use of the oils, lipids and/or fatty acids produced in the process according to the invention in feedstuffs or foodstuffs, cosmetics or pharmaceuticals.
    Type: Grant
    Filed: August 1, 2006
    Date of Patent: March 13, 2012
    Assignee: BASF Plant Science GmbH
    Inventors: Petra Cirpus, Jörg Bauer, Xiao Qiu, Guohai Wu, Nagamani Datla, Martin Truksa
  • Publication number: 20090234006
    Abstract: The invention relates to a method for producing arachidonic acid and/or eicosapentaenoic acid in useful transgenic plants, according to which nucleic acids, which encode polypeptides with ?-6-desaturase activity, ?-6-elongase activity or ?-5-desaturase activity, are introduced into the plants. As an added advantage, a gene that encodes a ?-3-desaturase is expressed in the useful plants. In an additional embodiment of the method, additional nucleic acid sequences, which encode polypeptides involved in the biosynthesis of the fatty acid or lipid metabolism, can be expressed in the plants. Particularly advantageous nucleic acid sequences are those that encode ?-8-desaturase activity, ?-12-desaturase activity, ?-15-desaturase activity, ?-4-desaturase activity, ?-9-elongase activity and/or ?-5-elongase activity. The invention also relates to the use of the oils, lipids and/or fatty acids that have been produced by said method in animal feed or foodstuffs, cosmetics or pharmaceutical products.
    Type: Application
    Filed: August 1, 2006
    Publication date: September 17, 2009
    Applicant: Basf Plant Science GmbH
    Inventors: Petra Cirpus, Jörg Bauer, Xiao Qiu, Guohai Wu, Nagamani Datla, Martin Truksa
  • Publication number: 20090222951
    Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in the seed of transgenic plants for introducing, into the organism, nucleic acids which encode polypeptides with ?3-desaturase, ?12-desaturase, ?6-desaturase, ?6-elongase, ?5-desaturase, ?5-elongase and/or ?4-desaturase activity, preferably polypeptides with ?6-desaturase, ?6-elongase and ?5-desaturase activity. The nucleic acid sequences are the sequences shown in SEQ ID NO: 11, SEQ ID NO: 27, SEQ ID NO: 193, SEQ ID NO: 197, SEQ ID NO: 199 and SEQ ID NO: 201. These nucleic acid sequences can advantageously be expressed in the organism, if appropriate together with further nucleic acid sequences which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acid sequences which encode a ?6-desaturase, a ?5-desaturase, ?4-desaturase, ?12-desaturase and/or ?6-elongase activity.
    Type: Application
    Filed: February 23, 2005
    Publication date: September 3, 2009
    Inventors: Petra Cirpus, Jörg Bauer, Xiao Qiu, Guohai Wu, Nagamani Datla