Patents by Inventor Nagarajan Chandramouli

Nagarajan Chandramouli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide inhibitors of smac protein binding to inhibitor of apoptosis proteins (IAP)
    Publication number: 20060052311
    Abstract: The present disclosure relates to XIAP inhibitor compounds of the formula I wherein the substituents are as described in the specification. The inventive compounds are useful as therapeutic agents for the treatment of proliferative disorders, including cancer.
    Type: Application
    Filed: August 12, 2005
    Publication date: March 9, 2006
    Inventors: Sushil Sharma, Leigh Zawel, Mark Palermo, Nagarajan Chandramouli, Kenneth Bair
  • Somatostatin peptides
    Patent number: 6225284
    Abstract: Somatostain analogues comprising the amino acid sequence of the formula (I): -(D/L)Trp-Lys-X1-X2, wherein X1 is a substituted Thr, Ser, Tyr, Glu or Cys residue and X2 is an &agr;-amino acid having an aromatic residue on the C&agr; side chain, or an amino acid unit selected from Dab, Dpr, Dpm, His (Bzl)HyPro, thienyl-Ala, cyclohexyl-Ala and t.-butyl-Ala, the residue Lys of said sequence corresponding to the residue Lys9 of the native somatostatin-14, in free form, in salt form or complexed with a detectable element have interesting pharmacological properties.
    Type: Grant
    Filed: December 29, 1997
    Date of Patent: May 1, 2001
    Assignee: Novartis AG
    Inventors: Rainer Albert, Wilfried Bauer, Christian Bruns, Nagarajan Chandramouli, Ian Lewis, Gisbert Weckbecker