Patents by Inventor Nagarajan Kuppuswamy

Nagarajan Kuppuswamy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PREPARATION OF 2-CYANOIMINO-1, 3-THIAZOLIDINE
    Publication number: 20100311983
    Abstract: The present invention relates to a process for the preparation of substantially pure 2-cyanoimino-1,3-thiazolidine of Formula (I) by cyclization of dimethyl N-cyanoiminodithiocarbonate with 2-aminoethanethiol or the salt thereof in the presence of an alkali metal alkoxide. Further the present invention provides a process for the preparation of substantially pure 2-cyanoimino-1,3-thiazolidine of Formula (I) by cyclization of dimethyl N-cyanoiminodithiocarbonate with 2-aminoethanethiol or the salt thereof in the presence of aqueous ammonia.
    Type: Application
    Filed: February 2, 2009
    Publication date: December 9, 2010
    Applicant: HIKAL LIMITED
    Inventors: Nagarajan Kuppuswamy, Rajender Pershad Gupta, Bhupathiraju Naga Satyanarayanaraju, Somu Madhava Reddy, Seranthimata Samshuddin, K. P. Jadhav, Sham Dhamnaskar
  • Process for the preparation of amino methyl cyclo alkane acetic acids
    Patent number: 7635717
    Abstract: This invention relates to an improved process for the preparation of amino methyl cyclo alkane acetic acids. This invention particularly relates to an improved process for the preparation of gabapentin (which is chemically known as 1-aminomethyl-1-cyclohexaneacetic acid), which is a very well known agent useful for the treatment of epilepsy and other cerebral disorders. In the chemical series of 1-amino methyl cyclo alkane-1-acetic acids, Gabapentin, which is 1-amino methyl cyclo hexane-1-acetic acid has been developed as a drug having anti convulsive properties.
    Type: Grant
    Filed: November 20, 2002
    Date of Patent: December 22, 2009
    Assignee: Hikal Limited
    Inventors: Nagarajan Kuppuswamy, Sivaramakrishnan Hariharan, Arulselvan Mariadas
  • Process for the preparation of gabalactam
    Patent number: 7632953
    Abstract: The present invention provides an improved process for the preparation of gabalactam of formula 1 that includes preparing an aqueous solution of an alkali or alkaline earth metal hydroxide, adding bromine to the resulting solution to give an appropriate alkali or alkaline earth metal hypobromite; adding an amide of the formula 4 aging the resultant mixture; heating the mixture to a temperature in a range of 80 to 100 degrees C.; extracting with nonpolar solvent and distilling under reduced pressure to obtain gabalactam.
    Type: Grant
    Filed: November 20, 2002
    Date of Patent: December 15, 2009
    Assignee: Hikal Limited
    Inventors: Nagarajan Kuppuswamy, Sivaramakrishnan Hariharan, Arulselvan Mariadas
  • Gabapentin analogues and process thereof
    Patent number: 7632864
    Abstract: The present invention relates to compounds trans (E) and cis (Z) stereoisomers of 4-t-butyl gabapentin of formula (11) and (12) and a process for the preparation of the said stereoisomers.
    Type: Grant
    Filed: October 20, 2006
    Date of Patent: December 15, 2009
    Assignees: Hikal Ltd., Indian Institute Of Science
    Inventors: Nagarajan Kuppuswamy, Sivaramakrishnan Hariharan, Venkatachalam Sankar Iyer, Suresh Babu Balakrishnan, Gopalakrishnan Krishnamurthi, Ananda Kuppanna, Muruga Poopati Raja Karuppiah, Balaram Padmanabhan, Aravinda Subrayashastry, Gouriamma Vasudev Prema, Shamala Narayanaswamy
  • Gabapentin analogues and process thereof
    Publication number: 20070123591
    Abstract: The present invention relates to compounds trans (E) and cis (Z) stereoisomers of 4-t-butyl gabapentin of formula (11) and (12) and a process for the preparation of the said stereoisomers.
    Type: Application
    Filed: October 20, 2006
    Publication date: May 31, 2007
    Inventors: Nagarajan Kuppuswamy, Sivaramakrishnan Hariharan, Venkatachalam Sankar Iyer, Suresh Babu Balakrishnan, Gopalakrishnan Krishnamurthi, Ananda Kuppanna, Muruga Poopati Raja Karuppiah, Balaram Padmanabhan, Aravinda Subrayashastry, Gouriamma Vasudev Prema, Shamala Narayanaswamy
  • Process for the preparation of amino methyl cyclo alkane acetic acids
    Publication number: 20060149099
    Abstract: This invention relates to an improved process for the preparation of amino methyl cyclo alkane acetic acids. This invention particularly relates to an improved process for the preparation of gabapentin (which is chemically known as 1-aminomethyl-1-cyclohexaneacetic acid), which is a very well known agent useful for the treatment of epilepsy and other cerebral disorders. In the chemical series of 1-amino methyl cyclo alkane-1-acetic acids, Gabapentin, which is 1-amino methyl cyclo hexane-1-acetic acid has been developed as a drug having anti convulsive properties.
    Type: Application
    Filed: February 9, 2006
    Publication date: July 6, 2006
    Inventors: Nagarajan Kuppuswamy, Sivaramakrishman Hariharan, Arulselvan Mariadas
  • Process for the preparation of gabalactam
    Publication number: 20060135789
    Abstract: This invention relates to an improved process for the preparation of gabalactum. Gabalactum is chemically known as 2-azaspiro(4,5)decan-3-one. Gabalactum has the structural formula 1 given.
    Type: Application
    Filed: November 20, 2002
    Publication date: June 22, 2006
    Inventors: Nagarajan Kuppuswamy, Sivaramakrishnan Hariharan, Arulselvan Mariadas
  • Gabapentin analogues and process thereof
    Publication number: 20050209332
    Abstract: The present invention relates to compounds cis (Z) and trans (E) stereoisomers of 4-t-butylgabapentin of formula (11) and (12) and a process for the preparation of the said stereoisomers.
    Type: Application
    Filed: March 15, 2005
    Publication date: September 22, 2005
    Inventors: Nagarajan Kuppuswamy, Sivaramakrishnan Hariharan, Venkatachalam Iyer, Suresh Balakrishnan, Gopalakrishnan Krishnamurthi, Ananda Kuppanna, Muruga Karuppiah, Balaram Padmanabhan, Aravinda Subrayashastry, Gouriamma Prema, Shamala Narayanaswamy