Abstract: An apparatus comprising: a membrane with a first side, a second side, and a pore that extends through the membrane; a processing system including a processor; and a memory that stores executable instructions that, when executed by the processing system, facilitate performance of operations, the operations comprising: electronic sensing of an electrical characteristic associated with a translocation of a test DNA through the pore, resulting in a sensed electrical characteristic; comparing the sensed electrical characteristic with a plurality of reference electrical characteristics, wherein each of the plurality of reference electrical characteristics is associated with a respective one of a plurality of reference features, and wherein the comparing results in a comparison result; and determining, based upon the comparison result, with which of the plurality of reference features a feature of the test DNA corresponds. Additional embodiments are disclosed.

Abstract: The use of DNA or other charged biomolecules for data storage can include the use of devices to manipulate the biomolecules in solution, e.g., to store and later to selectively read out selected samples of stored biomolecules. Systems and methods provided herein facilitate the electrical manipulation of DNA or other charged biomolecules for data storage or other applications by applying voltages to sets of electrodes arranged along the length of channels of microfluidic devices. The magnitudes and signs of the applied voltages can be controlled to collect DNA into a channel, to retain the collected DNA in the channel for later use, and then to expel the DNA from the channel for readout (e.g., by a pore sequencer integrated into the same microfluidic device as the channel). Such storage channels can have rectangular cross-sections or otherwise include electrodes having substantially planar geometry.

Abstract: Aspects of the subject disclosure may include, for example, an apparatus comprising: a membrane with a first side, a second side, and a pore that extends through the membrane; a processing system including a processor; and a memory that stores executable instructions that, when executed by the processing system, facilitate performance of operations, the operations comprising: electronic sensing of an electrical characteristic associated with a translocation of a test DNA through the pore, resulting in a sensed electrical characteristic; comparing the sensed electrical characteristic with a plurality of reference electrical characteristics, wherein each of the plurality of reference electrical characteristics is associated with a respective one of a plurality of reference features, and wherein the comparing results in a comparison result; and determining, based upon the comparison result, with which of the plurality of reference features a feature of the test DNA corresponds.