Patents by Inventor NAGNNATH KOKARE

NAGNNATH KOKARE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substantially pure vemurafenib and its salts
    Patent number: 10414764
    Abstract: The present invention relates to a process for the preparation substantially pure propane-1-sulfonicacid-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide or Vemurafenib of Formula (I).
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: September 17, 2019
    Assignee: SHILPA MEDICARE LIMITED
    Inventors: Purohit Prashant, Nagnnath Kokare, Veera Reddy Yenireddy, Chaturvedi Akshay Kant
  • SUBSTANTIALLY PURE VEMURAFENIB AND ITS SALTS
    Publication number: 20180334457
    Abstract: The present invention relates to a process for the preparation substantially pure propane-1-sulfonicacid-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide or Vemurafenib of Formula (I).
    Type: Application
    Filed: May 28, 2018
    Publication date: November 22, 2018
    Applicant: SHILPA MEDICARE LIMITED
    Inventors: PUROHIT PRASHANT, NAGNNATH KOKARE, VEERA REDDY YENIREDDY, CHATURVEDI AKSHAY KANT
  • SUBSTANTIALLY PURE VEMURAFENIB AND ITS SALTS
    Publication number: 20170320872
    Abstract: The present invention relates to a process for the preparation substantially pure propane-1-sulfonicacid-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide or Vemurafenib of Formula (I).
    Type: Application
    Filed: November 19, 2015
    Publication date: November 9, 2017
    Applicant: SHILPA MEDICARE LIMITED
    Inventors: PUROHIT PRASHANT, NAGNNATH KOKARE, VEERA REDDY YENIREDDY, CHATURVEDI AKSHAY KANT
  • Echothiophate iodide process
    Patent number: 9708352
    Abstract: The present invention relates to a process for preparation of Echothiophate Iodide (I). Echothiophate Iodide (I) obtained by the process of the present invention is obtained as new crystalline form designated as Form-SET. The process for preparation of Echothiophate Iodide (I) according to present invention is an ecofriendly process that avoids the use of hazardous solvent systems and provides Echothiophate Iodide (I) of high purity. Pharmaceutical composition of the said crystalline Form-SET of Echothiophate Iodide (I) of high purity is useful in the treatment of ocular disorders like Glaucoma.
    Type: Grant
    Filed: January 1, 2015
    Date of Patent: July 18, 2017
    Assignee: SHILPA MEDICARE LIMITED
    Inventors: Nagnnath Kokare, Venkatanarayana Bathula, Akshaykant Chaturvedi
  • Echothiophate Iodide Process
    Publication number: 20170002031
    Abstract: The present invention relates to a process for preparation of Echothiophate Iodide (I). Echothiophate Iodide (I) obtained by the process of the present invention is obtained as new crystalline form designated as Form-SET. The process for preparation of Echothiophate Iodide (I) according to present invention is an ecofriendly process that avoids the use of hazardous solvent systems and provides Echothiophate Iodide (I) of high purity. Pharmaceutical composition of the said crystalline Form-SET of Echothiophate Iodide (I) of high purity is useful in the treatment of ocular disorders like Glaucoma.
    Type: Application
    Filed: January 1, 2015
    Publication date: January 5, 2017
    Applicant: SHILPA MEDICARE LIMITED
    Inventors: NAGNNATH KOKARE, VENKATANARAYANA BATHULA, AKSHAYKANT CHATURVEDI
  • Process for preparation of 2-chloro--(4-chloro-3-pyridin-2-ylphenyl)-4-methylsulfonylbenzamide solid forms
    Patent number: 9278932
    Abstract: The present invention relates to crystalline 2-Chloro-N-(4-chloro-3-pyridin-2-ylphenyl)-4-methylsulfonylbenzamide (I) designated as Form-SV and process for preparation thereof. The invention further relates to pharmaceutical compositions comprising crystalline Form-SV or non-crystalline form of (2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide, useful in the treatment of cancer.
    Type: Grant
    Filed: March 5, 2014
    Date of Patent: March 8, 2016
    Assignee: SHILPA MEDICARE LIMITED
    Inventors: Rafiuddin Dr, Vinod Kumar Singh, Nagnnath Kokare, Akshaykant Chaturvedi
  • PROCESS FOR PREPARATION OF 2-CHLORO-N-(4-CHLORO-3-PYRIDIN-2-YLPHENYL)-4-METHYLSULFONYLBENZAMIDE SOLID FORMS
    Publication number: 20160060220
    Abstract: The present invention relates to crystalline 2-Chloro-N-(4-chloro-3-pyridin-2-ylphenyl)-4-methylsulfonylbenzamide (I) designated as Form-SV and process for preparation thereof. The invention further relates to pharmaceutical compositions comprising crystalline Form-SV or non-crystalline form of (2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide, useful in the treatment of cancer.
    Type: Application
    Filed: March 5, 2014
    Publication date: March 3, 2016
    Applicant: SHILPA MEDICARE LIMITED
    Inventors: RAFIUDDIN DR, VINOD KUMAR SINGH, NAGNNATH KOKARE, AKSHAYKANT CHATURVEDI