Patents by Inventor Naheed Kurji

Naheed Kurji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and system for differential drug discovery
    Patent number: 12580041
    Abstract: A method for differential drug discovery involves obtaining a receptor panel which specifies a multitude of targets and a multitude of anti-targets. The method further involves obtaining a small molecule compound (SMC) seed model and derivatizing a first multitude of candidate SMCs from the SMC seed model. For each of the candidate SMCs in the first multitude of candidate SMCs, first desired interactions between the candidate SMC and each of the multitude of targets are simulated, and first undesired interactions between the candidate SMC and each of the multitude of anti-targets are simulated. The method also involves obtaining a first SMC interaction score for each of the candidate SMCs in the first multitude of candidate SMCs based on the first desired interactions and the first undesired interactions, and based on the first SMC interaction score, determining whether at least a minimum score for a drug is reached.
    Type: Grant
    Filed: November 22, 2018
    Date of Patent: March 17, 2026
    Assignee: Cyclica Inc.
    Inventors: Stephen Scott Mackinnon, Vijay Shahani, Andreas Windemuth, Leonard Morayniss, Andrew Brereton, Naheed Kurji
  • METHOD AND SYSTEM FOR DIFFERENTIAL DRUG DISCOVERY
    Publication number: 20200357480
    Abstract: A method for differential drug discovery involves obtaining a receptor panel. The receptor panel specifies a multitude of targets and a multitude of anti-targets. The method further involves obtaining a small molecule compound (SMC) seed model and derivatizing a first multitude of candidate SMCs from the SMC seed model. For each of the candidate SMCs in the first multitude of candidate SMCs, first desired interactions between the candidate SMC and each of the multitude of targets are simulated. Further, for each of the candidate SMCs in the first multitude of candidate SMCs, first undesired interactions between the candidate SMC and each of the multitude of anti-targets are simulated.
    Type: Application
    Filed: November 22, 2018
    Publication date: November 12, 2020
    Inventors: Stephen Scott Mackinnon, Vijay Shahani, Andreas Windemuth, Leonard Morayniss, Andrew Brereton, Naheed Kurji