Patents by Inventor Nai Fang Wang

Nai Fang Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT
    Publication number: 20190022228
    Abstract: This invention relates to microparticles and/or nanoparticles containing a delivery agent and/or an active agent. This invention also relates to pharmaceutical formulations and solid dosage forms, including controlled release solid dosage forms of active agent and a delivery agent.
    Type: Application
    Filed: February 12, 2018
    Publication date: January 24, 2019
    Inventors: George Klein, Shingai Majuru, Puchun Liu, Steven Dinh, Jun Liao, Jongbin Lee, Halina Levchik, Ehud Arbit, Nikhil Dhoot, Jamila Harris, Nai Fang Wang
  • Arylsulfanyl compounds and compositions for delivering active agents
    Patent number: 9873667
    Abstract: Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are also provided.
    Type: Grant
    Filed: July 27, 2007
    Date of Patent: January 23, 2018
    Assignee: EMISPHERE TECHNOLOGIES INC.
    Inventors: Stephen Pusztay, Sushma Saraf, Nai Fang Wang
  • Intraoral dosage forms of glucagon
    Patent number: 8975227
    Abstract: The present invention provides a composition (e.g., a pharmaceutical composition) comprising at least one delivery agent compound and glucagon. Preferably, the composition includes a therapeutically effective amount of glucagon and the delivery agent compound. The composition of the present invention facilitates the delivery of glucagon and increases its bioavailability compared to administration without the delivery agent compound.
    Type: Grant
    Filed: July 17, 2006
    Date of Patent: March 10, 2015
    Assignee: Emisphere Technologies, Inc.
    Inventors: Nai Fang Wang, Puchun Liu, Steven Dinh, Michael M. Goldberg, Ehud Arbit
  • PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT
    Publication number: 20120189666
    Abstract: This invention relates to microparticles and/or nanoparticles containing a delivery agent and/or an active agent. This invention also relates to pharmaceutical formulations and solid dosage forms, including controlled release solid dosage forms of active agent and a delivery agent.
    Type: Application
    Filed: November 23, 2011
    Publication date: July 26, 2012
    Applicant: Emisphere Technologies, Inc.
    Inventors: Nikhil Dhoot, Halina Levchik, Shingai Majuru, George Klein, Jamila Harris, Puchun Liu, Steven Dinh, Jun Liao, Jongbin Lee, Ehud Arbit, Nai Fang Wang
  • Compounds and compositions for delivering active agents
    Patent number: 7744910
    Abstract: Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.
    Type: Grant
    Filed: September 13, 2006
    Date of Patent: June 29, 2010
    Assignee: Emisphere Technologies, Inc.
    Inventors: David Gschneidner, Andrea Leone-Bay, Eric Wang, Lynn Errigo, Koc-Kan Ho, Jeffrey Bruce Press, Nai Fang Wang, Pingwah Tang
  • Polymeric delivery agents and delivery agent compounds
    Patent number: 7727558
    Abstract: Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well.
    Type: Grant
    Filed: January 31, 2007
    Date of Patent: June 1, 2010
    Assignees: Emisphere Technologies, Inc., Virginia Commonwealth University
    Inventors: Sam J. Milstein, Eugene N. Barantsevitch, Nai Fang Wang, Jun Liao, John Smart, Richard Conticello, Raphael Ottenbrite
  • Compounds and compositions for delivering active agents
    Patent number: 7700775
    Abstract: Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: April 20, 2010
    Assignee: Emisphere Technologies, Inc.
    Inventors: Jun Liao, David Gschneidner, John J. Weidner, Nai Fang Wang
  • PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT
    Publication number: 20100055194
    Abstract: This invention relates to microparticles and/or nanoparticles containing a delivery agent and/or an active agent. This invention also relates to pharmaceutical formulations and solid dosage forms, including controlled release solid dosage forms of active agent and a delivery agent.
    Type: Application
    Filed: August 28, 2009
    Publication date: March 4, 2010
    Applicant: Emisphere Technologies, Inc.
    Inventors: Shingai Majuru, Puchun Liu, Steven Dinh, Jun Liao, Jongbin Lee, Ehud Arbit, Nikhil Dhoot, Halina Levchik, George Klein, Jamila Harris, Nai Fang Wang
  • ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS
    Publication number: 20090258817
    Abstract: Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are also provided.
    Type: Application
    Filed: July 27, 2007
    Publication date: October 15, 2009
    Inventors: Stephen Pusztay, Sushma Saraf, Nai Fang Wang
  • Intraoral Dosage Forms of Glucagon
    Publication number: 20080207514
    Abstract: The present invention provides a composition (e.g., a pharmaceutical composition) comprising at least one delivery agent compound and glucagon. Preferably, the composition includes a therapeutically effective amount of glucagon and the delivery agent compound. The composition of the present invention facilitates the delivery of glucagon and increases its bioavailability compared to administration without the delivery agent compound.
    Type: Application
    Filed: July 17, 2006
    Publication date: August 28, 2008
    Applicant: Emisphere Technologies, Inc.
    Inventors: Nai Fang Wang, Puchun Liu, Steven Dinh, Michael M. Goldberg, Ehud Arbit
  • Polymeric delivery agents and delivery agent compounds
    Patent number: 7208483
    Abstract: Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well.
    Type: Grant
    Filed: May 28, 2003
    Date of Patent: April 24, 2007
    Assignee: Emisphere Technologies, Inc.
    Inventors: Sam J. Milstein, Eugene N. Barantsevitch, Nai Fang Wang, Jun Liao, John E. Smart, Richard D. Conticello, Raphael M. Ottenbrite
  • Compounds and compositions for delivering active agents
    Patent number: 7186414
    Abstract: Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.
    Type: Grant
    Filed: June 30, 2005
    Date of Patent: March 6, 2007
    Assignee: Emisphere Technologies, Inc
    Inventors: David Gschneidner, Andrea Leone-Bay, Eric Wang, Lynn Errigo, Koc-Kan Ho, Jeffrey Bruce Press, Nai Fang Wang, Pingwah Tang
  • Compounds and compositions for delivering active agents
    Patent number: 6991798
    Abstract: Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.
    Type: Grant
    Filed: August 6, 1999
    Date of Patent: January 31, 2006
    Assignee: Emisphere Technologies, Inc.
    Inventors: David Gschneidner, Andrea Leone-Bay, Eric Wang, Lynn Errigo, Koc-Kan Ho, Jeffrey Bruce Press, Nai Fang Wang, Pingwah Tang
  • Active agent transport systems
    Patent number: 6916489
    Abstract: Methods for transporting a biologically active agent across a cellular membrane or a lipid bilayer. A first method includes the steps of: (a) providing a biologically active agent which can exist in a native conformational state, a denatured conformational state, and an intermediate conformational state which is reversible to the native state and which is conformationally between the native and denatured states; (b) exposing the biologically active agent to a complexing perturbant to reversibly transform the biologically active agent to the intermediate state and to form a transportable supramolecular complex; and (c) exposing the membrane or bilayer to the supramolecular complex, to transport the biologically active agent across the membrane or bilayer. The perturbant has a molecular weight between about 150 and about 600 daltons, and contains at least one hydrophilic moiety and at least one hydrophobic moiety.
    Type: Grant
    Filed: September 25, 2002
    Date of Patent: July 12, 2005
    Assignee: Emisphere Technologies, Inc.
    Inventors: Sam J. Milstein, Evgueni Barantsevitch, Andrea Leone-Bay, Nai Fang Wang, Donald J. Sarubbi, Noemi B Santiago
  • Compounds and compositions for delivering active agents
    Publication number: 20040097500
    Abstract: Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.
    Type: Application
    Filed: August 27, 2003
    Publication date: May 20, 2004
    Inventors: Jun Liao, David Gschneider, John J. Weidner, Nai Fang Wang
  • Polymeric delivery agents and delivery agent compounds
    Publication number: 20030232085
    Abstract: Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well.
    Type: Application
    Filed: May 28, 2003
    Publication date: December 18, 2003
    Applicants: Emisphere Technologies, Inc., Virginia Commonwealth University
    Inventors: Sam J. Milstein, Eugene N. Barantsevitch, Nai Fang Wang, Jun Liao, John E. Smart, Richard D. Conticello, Raphael M. Ottenbrite
  • Polymeric delivery agents and delivery agents compounds
    Patent number: 6627228
    Abstract: Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: September 30, 2003
    Assignee: Emisphere Technologies, Inc.
    Inventors: Sam J. Milstein, Eugene N. Barantsevitch, Nai Fang Wang, Jun Liao, John E. Smart, Richard D. Conticello, Raphael M. Ottenbrite
  • Active agent transport systems
    Publication number: 20030133953
    Abstract: Methods for transporting a biologically active agent across a cellular membrane or a lipid bilayer.
    Type: Application
    Filed: September 25, 2002
    Publication date: July 17, 2003
    Applicant: Emisphere Technologies, Inc.
    Inventors: Sam J. Milstein, Evgueni Barantsevitch, Andrea Leone-Bay, Nai Fang Wang, Donald J. Sarubbi, Noemi B. Santiago
  • Compounds and compositions for delivering active agents
    Patent number: 6428780
    Abstract: Modified amino acid compounds useful in the delivery of active agents are provided. The active agents can be peptides. Methods of administration, such as oral, subcutaneous, sublingual, and intranasal administration are provided, and methods of preparation of the modified amino acid compound are provided.
    Type: Grant
    Filed: May 5, 1999
    Date of Patent: August 6, 2002
    Assignee: Emisphere Technologies, Inc.
    Inventors: Andrea Leone-Bay, Koc-Kan Ho, Donald J. Sarubbi, Sam J. Milstein, Nai Fang Wang
  • Orally deliverable supramolecular complex
    Patent number: 6348207
    Abstract: Methods for transporting a biologically active agent across a cellular membrane or a lipid bilayer. A first method includes the steps of: (a) providing a biologically active agent which can exist in a native conformational state, a denatured conformational state, and an intermediate conformational state which is reversible to the native state and which is conformationally between the native and denatured states; (b) exposing the biologically active agent to a complexing perturbant to reversibly transform the biologically active agent to the intermediate state and to form a transportable supramolecular complex; and (c) exposing the membrane or bilayer to the supramolecular complex, to transport the biologically active agent across the membrane or bilayer. The perturbant has a molecular weight between about 150 and about 600 daltons, and contains at least one hydrophilic moiety and at least one hydrophobic moiety.
    Type: Grant
    Filed: September 30, 1997
    Date of Patent: February 19, 2002
    Assignee: Emisiphere Technologies, Inc.
    Inventors: Sam J. Milstein, Evgueni Barantsevitch, Andrea Leone-Bay, Nai Fang Wang, Donald J. Sarubbi, Noemi B Santiago