Abstract: The present invention provides a cartilage filling system and a surgical instrument kit including the same. The cartilage filling system comprises a filling push-rod, a filling member, a filling hopper, and a filtering adapter. The filling member comprises a syringe shaped as a hollow cylinder and comprising a first end portion and a second end portion, wherein the syringe has a first inner diameter; and a grip portion provided on the syringe. The filling hopper comprises a connecting member having an outer surface penetrated by a vent hole; and a hopper member comprising a wide portion and a narrow portion and having a second inner diameter, wherein the wide portion is connected to the connecting member, the narrow portion is detachably connected to the first end portion, and the second inner diameter is gradually reduced from the wide portion to the narrow portion, at which the second inner diameter is equal to the first inner diameter.

Abstract: The present disclosure provides a temperature-responsive composition including a nitric oxide donor and a carrier. The nitric oxide donor is a pH-dependent material, and the carrier is provided for carrying the nitric oxide donor with an effective amount. The carrier includes a protective agent and an organic protic acid. A transition temperature of the temperature-responsive composition is larger than or equal to 28° C. and less than or equal to 37° C.