Patents by Inventor Naibedya Chattopadhyay
Naibedya Chattopadhyay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10576078Abstract: The present invention relates to method of treating chronic myeloid leukemia (CML) or drug resistant CML comprising, administering to human being or any other mammal or animal in need thereof, a therapeutically effective amount of Clofazimine (CFZ) or its pharmaceutically acceptable derivative, analogue, salt or composition; or a combination of a therapeutically effective amount of Clofazimine (CFZ) or its pharmaceutically acceptable derivative, analogue, salt or composition with a tyrosine kinase inhibitor (TKI). The invention also provides the kit for treatment of CML or drug resistant CML.Type: GrantFiled: August 30, 2018Date of Patent: March 3, 2020Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Sabyasachi Sanyal, Harish Kumar, Naibedya Chattopadhyay, Ravishankar Ramachandran, Arun Kumarv Trivedi, Sonal Shree, Anagha Ashok Gurjar, Sourav Chattopadhyay, Sapana Kushwaha, Abhishek Kumar Singh, Shikha Dubey, Kiran Lata, Riyazuddin Mohammed, Jiaur Rahaman Gayen, Anil Kumar Tripathi
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Publication number: 20190350928Abstract: The present invention relates to method of treating chronic myeloid leukemia (CML) or drug resistant CML comprising, administering to human being or any other mammal or animal in need thereof, a therapeutically effective amount of Clofazimine (CFZ) or its pharmaceutically acceptable derivative, analogue, salt or composition; or a combination of a therapeutically effective amount of Clofazimine (CFZ) or its pharmaceutically acceptable derivative, analogue, salt or composition with a tyrosine kinase inhibitor (TKI). The invention also provides the kit for treatment of CML or drug resistant CML.Type: ApplicationFiled: August 30, 2018Publication date: November 21, 2019Inventors: Sabyasachi Sanyal, Harish Kumar, Naibedya Chattopadhyay, Ravishankar Ramachandran, Arun Kumarv Trivedi, Sonal Shree, Anagha Ashok Gurjar, Sourav Chattopadhyay, Sapana Kushwaha, Abhishek Kumar Singh, Shikha Dubey, Kiran Lata, Riyazuddin Mohammed, Jiaur Rahaman Gayen, Anil Kumar Tripathi
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Patent number: 10292994Abstract: The present invention relates to bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders. The present invention relates in the field of pharmaceutical composition that provides new plant extracts, their fractions and pure compound isolated from natural sources that are useful for the prevention and/or treatment of various medical indications associated with estrogen dependent or independent diseases or syndromes or disorders preferably in the prevention or treatment of estrogen dependent or independent diseases or syndromes or disorders caused in humans and animals, and achievement of peak bone mass during skeletal growth and health in humans and animals.Type: GrantFiled: April 25, 2012Date of Patent: May 21, 2019Assignee: Council of Scientific & Industrial ResearchInventors: Rakesh Maurya, Preety Dixit, Ritu Trivedi, Vikram Khedgikar, Jyoti Gautam, Avinash Kumar, Divya Singh, Shelendra Pratap Singh, Wahajuddin, Girish Kumar Jain, Naibedya Chattopadhyay
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Patent number: 9994515Abstract: The present invention relates to substituted aryl naphthyl methanone oximes of general formula (I), their process for preparation and their derivatives, salts, pharmaceutical composition thereof and their use in treatment of chronic myelogenous leukemia, acute myelogenous leukemia, lymphoma, multiple myeloma, solid tumor forming cell-lines including such as breast cancer, endometrial cancer colon cancer, prostate cancer and killing of drug resistant cancer stem cells, as subject in need thereof.Type: GrantFiled: August 29, 2014Date of Patent: June 12, 2018Assignee: Council of Scientific & Industrial ResearchInventors: Sabyasachi Sanyal, Atul Kumar, Naibedya Chattopadhyay, Jawahar Lal, Arun Kumar Trivedi, Dipak Datta, Srikanta Kumar Rath, Tahseen Akhtar, Shailendra Kumar Dhar Dwivedi, Manisha Yadav, Bandana Chakravarti, Abhishek Kumar Singh, Jay Sharan Mishra, Nidhi Singh, Anil Kumar Tripathi
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Publication number: 20160304442Abstract: The present invention relates to substituted aryl naphthyl methanone oximes of general formula (I), their process for preparation and their derivatives, salts, pharmaceutical composition thereof and their use in treatment of chronic myelogenous leukemia, acute myelogenous leukemia, lymphoma, multiple myeloma, solid tumor forming cell- lines including such as breast cancer, endometrial cancer colon cancer, prostate cancer and killing of drug resistant cancer stem cells, as subject in need thereof.Type: ApplicationFiled: August 29, 2014Publication date: October 20, 2016Inventors: Sabyasachi Sanyal, Atul Kumar, Naibedya Chattopadhyay, Jawahar Lal, Arun Kumar Trivedi, Dipak Datta, Srikanta Kumar Rath, Tahseen Akhtar, Shailendra Kumar Dhar Dwivedi, Manisha Yadav, Bandana Chakravarti, Abhishek Kumar Singh, Jay Sharan Mishra, Nidhi Singh, Anil Kumar Tripathi
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Publication number: 20160193240Abstract: The present invention relates to ulmoside A as a novel small molecule adiponectin receptor agonist useful for prevention or cure of metabolic diseases. The present invention further relates to the use of ulmoside-A (ULMA) ((2S,3S)-(+)-3?,4?,5,7-tetrahydroxydihydroflavonol-6-C-?-D-glucopyranoside) for alleviation, management or prevention or treatment of steroid-induced metabolic disorder. The present invention further relates to a pharmaceutical composition useful for prevention and/or treatment of various medical indications associated with metabolic diseases caused in humans and animals.Type: ApplicationFiled: July 14, 2014Publication date: July 7, 2016Inventors: Sabyasachi Sanyal, Naibedya Chattopadhyay, Rakesh Maurya, Jiaur Rahaman Gayen, Smrati Bhadauria, Arun Kumar Trivedi, Abhishek Kumar Singh, Jay Sharan Mishra, Rashmi Kumari, Kunal Sharan, Parvez Mohammad Khan, Kainat Khan, Nidhi Singh, Shailendra Kumar Dhar Dwivedi, Manisha Yadav, Preety Dixit, Devendra Pratap Mishra, Sharad Sharma, Ram Arya Kamal
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Publication number: 20140213535Abstract: Flavonol compounds, pharmaceutical compositions of the compounds and methods for treating bone disorders by administering the pharmaceutical composition by oral, intravenous, subcutaneous, intra-peritoneal or intramuscular route.Type: ApplicationFiled: January 20, 2014Publication date: July 31, 2014Applicant: Council of Scientific & Industrial ResearchInventors: Rakesh MAURYA, Preeti RAWAT, Kunal SHARAN, Jawed Akhtar SIDDIQUI, Gaurav SWARNKAR, Geetanjali MISHRA, Lakshmi MANICKAVASAGAM, Girish Kumar JAIN, Kamal Ram ARYA, Naibedya CHATTOPADHYAY
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Patent number: 8686028Abstract: The present invention relates to novel substituted benzfurochromenes and related compounds having the general formula (I), salts and chiral, achiral derivatives thereof; wherein R1, R2, R3, R4, R5, R6, R7, R8 are independently selected from the groups consisting of hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkoxyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted alkylthio, optionally substituted amino, optionally substituted acylamino, optionally substituted arylamino, optionally substituted acylthio, optionally substituted acyl, optionally substituted aroyl, optionally substituted acyloxy, optionally substituted thioamido, halogens, nitriles, esters, hydroxy, mercapto, carbontrifluoride, nitro but not limited to this; wherein R1R2 or R2R3 or R6R7 may be connected and form either a five membered ring or a six membered ring such as optionally substituted furan, optionally substituted dihydrofuran, optionally substitutedType: GrantFiled: May 14, 2009Date of Patent: April 1, 2014Assignee: Council of Scientific & Industrial ResearchInventors: Atul Goel, Amit Kumar, Sumit Chaurasia, Divya Singh, Abnish Kumar Gautam, Rashmi Pandey, Ritu Trivedi, Man Mohan Singh, Naibedya Chattopadhyay, Lakshmi Manickavasagam, Girish Kumar Jain, Anil Kumar Dwivedi
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Publication number: 20140079834Abstract: The present invention relates to bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders. The present invention relates in the field of pharmaceutical composition that provides new plant extracts, their fractions and pure compound isolated from natural sources that are useful for the prevention and/or treatment of various medical indications associated with estrogen dependent or independent diseases or syndromes or disorders preferably in the prevention or treatment of estrogen dependent or independent diseases or syndromes or disorders caused in humans and animals, and achievement of peak bone mass during skeletal growth and health in humans and animals.Type: ApplicationFiled: April 25, 2012Publication date: March 20, 2014Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Rakesh Maurya, Preety Dixit, Ritu Trivedi, Vikram Khedgikar, Jyoti Gautam, Avinash Kumar, Divya Singh, Sheelendra Pratap Singh, (none) Wahajuddin, Girish Kumar Jain, Naibedya Chattopadhyay
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Patent number: 8669232Abstract: The present invention provides a flavonol compound and a bioactive extract/fraction from Ulmus wallichiana useful for the management or prevention or treatment of bone disorders. Said extract/fraction comprising marker compounds of general formula 2, K058: R1?R2?OH K012: R1?R2?OH, 2,3 double bond K068: R1?R2?H KIOOi R1?OH, R2?H mula 2 Wherein the marker compounds K012, K058, K068, K1OO ranges 6.7-12%, 1.7-4.5%, 0.6-1.2%, 1.7-4.5% respectively in alcoholic extract and a process of extraction thereof. According to another aspect of the invention provides a pharmaceutical composition comprising the said compound. The present invention further provides a method of treating bone disorders by administering the pharmaceutical composition by oral, intravenous, subcutaneous, intra-peritoneal or intramuscular route.Type: GrantFiled: March 3, 2009Date of Patent: March 11, 2014Assignee: Council of Scientific & Industrial ResearchInventors: Rakesh Maurya, Preeti Rawat, Kunal Sharan, Jawed Akhtar Siddiqui, Gaurav Swarnkar, Geetanjali Mishra, Lakshmi Manickavasagam, Girish Kumar Jain, Kamal Ram Arya, Naibedya Chattopadhyay
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Patent number: 8496964Abstract: The present invention relates to a microcapsule for controlled release of flavanoid compound and a process for preparation thereof. The microcapsule comprising a core particle consisting of a calcium salt, Pluronic F68 [poly (ethylene oxide-co-polypropylene oxide), block poly oxyethylene-polypropylene block copolymer], loaded with a flavanoid compound, the resulting core particle having a plurality of alternate layers of cationic and anionic polyelectrolytes adsorbed thereon and an outer layer formed by a bile salt, wherein the flavanoid is ranging between 10 to 96% by weight.Type: GrantFiled: February 26, 2010Date of Patent: July 30, 2013Assignee: Council of Scientific & Industrial ResearchInventors: Prabhat Ranjan Mishra, Ritu Trivedi, Girish Kumar Gupta, Avinash Kumar, Varsha Gupta, Srikanta Kumar Rath, Kamini Srivastava, Naibedya Chattopadhyay, Anil Kumar Dwivedi
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Publication number: 20120003273Abstract: The present invention relates to novel substituted benzfurochromenes and related compounds having the general formula (I), salts and chiral, achiral derivatives thereof; wherein R1, R2, R3, R4, R5, R6, R7, R8 are independently selected from the groups consisting of hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkoxyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted alkylthio, optionally substituted amino, optionally substituted acylamino, optionally substituted arylamino, optionally substituted acylthio, optionally substituted acyl, optionally substituted aroyl, optionally substituted acyloxy, optionally substituted thioamido, halogens, nitriles, esters, hydroxy, mercapto, carbontrifluoride, nitro but not limited to this; wherein R1R2 or R2R3 or R6R7 may be connected and form either a five membered ring or a six membered ring such as optionally substituted furan, optionally substituted dihydrofuran, optionally substitutedType: ApplicationFiled: May 14, 2009Publication date: January 5, 2012Inventors: Atul Goel, Amit Kumar, Sumit Chaurasia, Divya Singh, Abnish Kumar Gautam, Rashmi Pandey, Ritu Trivedi, Man Mohan Singh, Naibedya Chattopadhyay, Lakshmi Manickavasagam, Girish Kumar Jain, Anil Kumar Dwivedi
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Publication number: 20110305754Abstract: The present invention relates to a microcapsule for controlled release of flavanoid compound and a process for preparation thereof. The microcapsule comprising a core particle consisting of a calcium salt, Pluronic F68 [poly (ethylene oxide-co-polypropylene co-polypropylene oxide), block poly oxyethylene-polypropylene block copolymer], loaded with a flavanoid compound, the resulting core particle having a plurality of alternate layers of cationic and anionic polyelectrolytes adsorbed thereon and an outer layer formed by a bile salt, wherein the flavanoid is ranging between 10 to 96% by weight.Type: ApplicationFiled: February 26, 2010Publication date: December 15, 2011Inventors: Prabhat Ranjan Mishra, Ritu Trivedi, Girish Kumar Gupta, Avinash Kumar, Varsha Gupta, Srikanta Kumar Rath, Kamini Srivastava, Naibedya Chattopadhyay, Anil Kumar Dwivedi
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Publication number: 20110112042Abstract: The present invention provides a flavonol compound and a bioactive extract/fraction from Ulmus wallichiana useful for the management or prevention or treatment of bone disorders. Said extract/fraction comprising marker compounds of general formula 2, K058: R1?R2?0H K012: R1?R2?OH, 2,3 double bond K068: R1?R2?H KIOOi R1?OH, R2?H mula 2 Wherein the marker compounds K012, K058, K068, K100 ranges 6.7-12%, 1.7-4.5%, 0.6-1.2%, 1.7-4.5% respectively in alcoholic extract and a process of extraction thereof. According to another aspect of the invention provides a pharmaceutical composition comprising the said compound. The present invention further provides a method of treating bone disorders by administering the pharmaceutical composition by oral, intravenous, subcutaneous, intra-peritoneal or intramuscular route.Type: ApplicationFiled: March 3, 2009Publication date: May 12, 2011Inventors: Rakesh Maurya, Preeti Rawat, Kunal Sharan, Jawed Akhtar Siddiqui, Gaurav Swarnkar, Geetanjali Mishra, Lakshmi Manickavasagam, Girish Kumar Jain, Kamal Ram Arya, Naibedya Chattopadhyay