Patents by Inventor Nakia SPENCER

Nakia SPENCER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glutaminase inhibitor therapy
    Patent number: 11786500
    Abstract: Disclosed herein are methods of treating a tumor or cancer in a subject whose tumor or cancer cells express low levels of asparagine synthetase (ASNS), and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production or a glutaminase inhibitor to a subject with a tumor or cancer.
    Type: Grant
    Filed: May 21, 2021
    Date of Patent: October 17, 2023
    Assignee: Board of Regents, The University of Texas System
    Inventors: Timothy Heffernan, Jeffrey Kovacs, Nakia Spencer, Christopher Bristow
  • GLUTAMINASE INHIBITOR THERAPY
    Publication number: 20220016069
    Abstract: Disclosed herein are methods of treating a tumor or cancer in a subject whose tumor or cancer cells express low levels of asparagine synthetase (ASNS), and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production or a glutaminase inhibitor to a subject with a tumor or cancer.
    Type: Application
    Filed: May 21, 2021
    Publication date: January 20, 2022
    Inventors: Timothy HEFFERNAN, Jeffrey KOVACS, Nakia SPENCER, Christopher BRISTOW
  • Glutaminase inhibitor therapy
    Patent number: 11045443
    Abstract: Disclosed herein are methods of treating a tumor or cancer in a subject whose tumor or cancer cells express low levels of asparagine synthetase (ASNS), and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production or a glutaminase inhibitor to a subject with a tumor or cancer.
    Type: Grant
    Filed: June 3, 2020
    Date of Patent: June 29, 2021
    Assignee: Board of Regents, The University of Texas System
    Inventors: Timothy Heffernan, Jeffrey Kovacs, Nakia Spencer, Christopher Bristow
  • GLUTAMINASE INHIBITOR THERAPY
    Publication number: 20200368196
    Abstract: Disclosed herein are methods of treating a tumor or cancer in a subject whose tumor or cancer cells express low levels of asparagine synthetase (ASNS), and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production or a glutaminase inhibitor to a subject with a tumor or cancer.
    Type: Application
    Filed: June 3, 2020
    Publication date: November 26, 2020
    Inventors: Timothy HEFFERNAN, Jeffrey KOVACS, Nakia SPENCER, Christopher BRISTOW
  • Glutaminase inhibitor therapy
    Patent number: 10722487
    Abstract: Disclosed herein are methods of treating a tumor or cancer in a subject whose tumor or cancer cells express low levels of asparagine synthetase (ASNS), and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production or a glutaminase inhibitor to a subject with a tumor or cancer.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: July 28, 2020
    Assignee: Board of Regents, The University of Texas System
    Inventors: Timothy Heffernan, Jeffrey Kovacs, Nakia Spencer, Christopher Bristow
  • GLUTAMINASE INHIBITOR THERAPY
    Publication number: 20190274993
    Abstract: Disclosed herein are methods of treating a tumor or cancer in a subject whose tumor or cancer cells express low levels of asparagine synthetase (ASNS), and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production or a glutaminase inhibitor to a subject with a tumor or cancer.
    Type: Application
    Filed: October 18, 2018
    Publication date: September 12, 2019
    Inventors: Timothy HEFFERNAN, Jeffrey KOVACS, Nakia SPENCER, Christopher BRISTOW
  • GLUTAMINASE INHIBITOR THERAPY
    Publication number: 20190134032
    Abstract: Disclosed herein are methods of treating a subject having an altered NRF2/KEAP1 pathway, and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production or a glutaminase inhibitor to a subject.
    Type: Application
    Filed: August 22, 2018
    Publication date: May 9, 2019
    Inventors: Timothy P. HEFFERNAN, Carlo TONIATTI, Jeffrey KOVACS, Virginia GIULIANI, Nakia SPENCER, Maria Emilia DI FRANCESCO, Christopher A. BRISTOW