Patents by Inventor Nalinikanth Kotagiri

Nalinikanth Kotagiri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression and Secretion of UV Absorbent Material from Transformed Bacteria
    Publication number: 20220275411
    Abstract: A genetically modified strain of commensal bacteria Staphylococcus epidermidis is provided which produces a material with UV absorbing properties. The material with UV absorbing properties may be a mycosporine-like amino acid such as shinorine.
    Type: Application
    Filed: February 17, 2022
    Publication date: September 1, 2022
    Applicant: University of Cincinnati
    Inventors: Nalinikanth Kotagiri, Tushar Madaan
  • IMAGING AND TREATMENT OF PATHOPHYSIOLOGIC CONDITIONS BY CERENKOV RADIATION
    Publication number: 20220202961
    Abstract: The present disclosure discloses methods and compositions for administering Cerenkov radiation-induced therapy (CRIT).
    Type: Application
    Filed: October 1, 2021
    Publication date: June 30, 2022
    Inventors: Samuel Achilefu, Nalinikanth Kotagiri
  • Imaging and treatment of pathophysiologic conditions by Cerenkov radiation
    Patent number: 11135316
    Abstract: The present disclosure discloses methods and compositions for administering Cerenkov radiation-induced therapy (CRIT). In an aspect, the invention encompasses a composition comprising at least two radiation-sensitive molecules. In another aspect, the invention encompasses a composition comprising a radiation-sensitive molecule and a targeting agent. In still another aspect, the invention encompasses a method for administering Cerenkov radiation-induced therapy (CRIT) to a target tissue in a subject. The method comprises administering to the subject an effective amount of a composition B comprising at least one radiation-sensitive molecule and administering to the subject an amount of a Cerenkov radiation (CR)-emitting radionuclide effective to activate the radiation-sensitive molecule, thereby administering CRIT to the target tissue in the subject.
    Type: Grant
    Filed: February 2, 2015
    Date of Patent: October 5, 2021
    Assignee: Washington University
    Inventors: Samuel Achilefu, Nalinikanth Kotagiri
  • IMAGING AND TREATMENT OF PATHOPHYSIOLOGIC CONDITIONS BY CERENKOV RADIATION
    Publication number: 20170007724
    Abstract: The present disclosure discloses methods and compositions for A administering Cerenkov radiation-induced therapy (GRIT). In an aspect, the invention encompasses a composition comprising at least two radiation-sensitive molecules. In another aspect, the invention encompasses a composition comprising a radiation-sensitive molecule and a targeting agent. In still another aspect, the invention encompasses a method for administering Gerenkov radiation-induced therapy (GRIT) to a target tissue in a subject. The method comprises administering to the subject an effective amount of a composition B comprising at least one radiation-sensitive molecule and administering to the subject an amount of a Gerenkov radiation (GR)-emitting radionuclide effective to activate the radiation-sensitive molecule, thereby administering GRIT to the target tissue in the subject.
    Type: Application
    Filed: February 2, 2015
    Publication date: January 12, 2017
    Applicant: WASHINGTON UNIVERSITY
    Inventors: Samuel Achilefu, Nalinikanth Kotagiri