Patents by Inventor Nallathamby Devasahayam

Nallathamby Devasahayam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9874622
    Abstract: A system and method for transporting a hyperpolarized substance is disclosed. A transport vessel for transporting such a hyperpolarized substance includes a vessel housing, a chamber formed within the vessel housing that is configured to receive a container holding a hyperpolarized substance, and an electromagnet configured to generate a magnetic containment field about the chamber when a current is supplied thereto, the magnetic containment field comprising a homogeneous magnetic field. The transport vessel also includes a non-magnetic power source to supply the current to the electromagnet and a control circuit configured to selectively interrupt the supply of current to the electromagnet so as to control generation of the magnetic containment field, with the transport vessel being magnetically inert when the supply of current to the electromagnet is interrupted by the control circuit.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: January 23, 2018
    Assignee: General Electric Company
    Inventors: Timothy William Skloss, Jonathan Alan Murray, Jan Henrik Ardenkjaer-Larsen, Murali K. Cherukuri, Marcelino Bernardo, Nallathamby Devasahayam
  • Publication number: 20150091573
    Abstract: A system and method for transporting a hyperpolarized substance is disclosed. A transport vessel for transporting such a hyperpolarized substance includes a vessel housing, a chamber formed within the vessel housing that is configured to receive a container holding a hyperpolarized substance, and an electromagnet configured to generate a magnetic containment field about the chamber when a current is supplied thereto, the magnetic containment field comprising a homogeneous magnetic field. The transport vessel also includes a non-magnetic power source to supply the current to the electromagnet and a control circuit configured to selectively interrupt the supply of current to the electromagnet so as to control generation of the magnetic containment field, with the transport vessel being magnetically inert when the supply of current to the electromagnet is interrupted by the control circuit.
    Type: Application
    Filed: September 27, 2013
    Publication date: April 2, 2015
    Applicants: General Electric Company, The United States of America, As Represented By The Secretary, Department of Health and Human Serv
    Inventors: Timothy William Skloss, Jonathan Alan Murray, Jan Henrik Ardenkjaer-Larsen, Murali K. Cherukuri, Marcelino Bernardo, Nallathamby Devasahayam
  • Patent number: 8712499
    Abstract: An echo-based single point imaging (ESPI) system (10) providing high-resolution oxygen images of a sample is disclosed. The ESPI system (10) employs spin echo detection of the resonance from a spin probe and concurrent Single Point Imaging (SPI) for spatial encoding of the oxygen concentration within the sample. Images are derived by comparing spin echo intensities of two images reconstructed at two time points selected at identical time intervals on either side of a refocusing pulse, eliminating artifacts associated with sample magnetic susceptibility and field inhomogeneity effects.
    Type: Grant
    Filed: November 25, 2009
    Date of Patent: April 29, 2014
    Assignee: The United States of America as represented by the Secretary, Department of Health and Human Services
    Inventors: Sankaran Subramanian, Nallathamby Devasahayam, Shingo Matsumoto, James B. Mitchell, Murali Krishna Cherukuri, John A. Cook
  • Patent number: 8269496
    Abstract: An electron paramagnetic resonance imaging system that includes means for continuously irradiating a sample with RF irradiation; means for imposing on the sample a sinusoidally varying magnetic field along with rotating gradients for spatial encoding; means for directly detecting signal data from the sample, without using field modulation, while irradiating the sample with RF radiation continuously, the means for directly detecting having means for sweeping the sinusoidally varying magnetic field; and means for processing the signal data, using means including a digital signal processor.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: September 18, 2012
    Assignee: The United States of America, as represented by the Secretary of the Department of Health and Human Services
    Inventors: Sankaran Subramanian, Nallathamby Devasahayam, Janusz Koscielniak, James B. Mitchell, Murali Krishna Cherukuri
  • Patent number: 8242778
    Abstract: An electron paramagnetic resonance imaging system that includes means for continuously irradiating a sample with RF irradiation; means for imposing on the sample a sinusoidally varying magnetic field along with rotating gradients for spatial encoding; means for directly detecting signal data from the sample, without using field modulation, while irradiating the sample with RF radiation continuously, the means for directly detecting having means for sweeping the sinusoidally varying magnetic field; and means for transmitting, receiving and processing the signal data, using means including a digital signal processor.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: August 14, 2012
    Assignee: The Government of the United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Sankaran Subramanian, Nallathamby Devasahayam, Janusz Koscielniak, James B. Mitchell, Murali K. Cherukuri
  • Publication number: 20110313279
    Abstract: An echo-based single point imaging (ESPI) system (10) providing high-resolution oxygen images of a sample is disclosed. The ESPI system (10) employs spin echo detection of the resonance from a spin probe and concurrent Single Point Imaging (SPI) for spatial encoding of the oxygen concentration within the sample. Images are derived by comparing spin echo intensities of two images reconstructed at two time points selected at identical time intervals on either side of a refocusing pulse, eliminating artifacts associated with sample magnetic susceptibility and field inhomogeneity effects.
    Type: Application
    Filed: November 25, 2009
    Publication date: December 22, 2011
    Applicant: National Institute of Health
    Inventors: Sankaran Subramanian, Nallathamby Devasahayam, Shingo Matsumoto, James B. Mitchell, Murali Krishna Cherukuri, John A. Cook
  • Publication number: 20110109313
    Abstract: An electron paramagnetic resonance imaging system that includes means for continuously irradiating a sample with RF irradiation; means for imposing on the sample a sinusoidally varying magnetic field along with rotating gradients for spatial encoding; means for directly detecting signal data from the sample, without using field modulation, while irradiating the sample with RF radiation continuously, the means for directly detecting having means for sweeping the sinusoidally varying magnetic field; and means for transmitting, receiving and processing the signal data, using means including a digital signal processor.
    Type: Application
    Filed: June 4, 2010
    Publication date: May 12, 2011
    Applicant: Government of the US, as Represented by the Secretary, Department of Health and Human Services
    Inventors: Sankaran Subramanian, Nallathamby Devasahayam, Janusz Koscielniak, James B. Mitchell, Murali K. Cherukuri
  • Publication number: 20100148776
    Abstract: An electron paramagnetic resonance imaging system that includes means for continuously irradiating a sample with RF irradiation; means for imposing on the sample a sinusoidally varying magnetic field along with rotating gradients for spatial encoding; means for directly detecting signal data from the sample, without using field modulation, while irradiating the sample with RF radiation continuously, the means for directly detecting having means for sweeping the sinusoidally varying magnetic field; and means for processing the signal data, using means including a digital signal processor.
    Type: Application
    Filed: June 28, 2007
    Publication date: June 17, 2010
    Applicant: THE GOV'T OF THE U.S., REPRESENTY BY THE SECRETARY OF THE DEPT OF HEALTH AND HUMAN SERVICES
    Inventors: Sankaran Subramanian, Nallathamby Devasahayam, Janusz Koscielniak, James B. Mitchell, Murali Krishna Cherukuri
  • Patent number: 6573720
    Abstract: A radiofrequency (RF) coil design, suitable for detecting time domain electron paramagnetic resonance (EPR) responses from spin probes after pulsed excitation using radiofrequency irradiation (60-400 MHz), is configured in an array of numerous surface coils of appropriate diameters connected in a parallel or axial configuration with appropriate spacing between individual surface coils to form a volume type resonator.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: June 3, 2003
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Nallathamby Devasahayam, James B. Mitchell, Angelo Russo, John Cook, Mobae Afeworki, Rolf G. Tschudin, Sankaran Subramanian, Ramachandran Murugesan, Frank S. Harrington, Murali K. Cherukuri