Patents by Inventor Nam Hyun Lyu

Nam Hyun Lyu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Streptomyces sp producing tautomycetin and immunosuppressant comprising tautomycetin as active ingredient
    Patent number: 6608045
    Abstract: The present invention relates to Streptomyces sp. producing tautomycetin which possesses an immunosuppressive or antibacterial activities, a process for preparing tautomycetin from the said microorganism, and an immunosuppressant or immunosuppressive pharmaceutical composition comprising tautomycetin as an active ingredient which suppresses interleukin-2 production, CD69 and interleukin-2 receptor(IL-2R) expression on the cell surface, and graft rejection in the organ transplantation. The present inventors isolated a soil microorganism which produces a substance possessing antibiotic and immunosuppressive activities, and identified the said microorganism and substance as a novel Streptomyces sp. and tautomycetin, respectively.
    Type: Grant
    Filed: May 17, 1999
    Date of Patent: August 19, 2003
    Assignee: Chong Kun Dang Corporation
    Inventors: Hyoung Sik Chun, Jong Gwan Kim, Hung Bae Chang, Seung Kee Moon, Hyeog Jin Son, Chung Il Hong, Jung Woo Kim, Nam Hyun Lyu
  • STREPTOMYCES SP PRODUCING TAUTOMYCETIN AND IMMUNOSUPPRESSANT COMPRISING TAUTOMYCETIN AS ACTIVE INGREDIENT
    Publication number: 20010016599
    Abstract: The present invention relates to Streptomyces sp. producing tautomycetin which possesses an immunosuppressive or antibacterial activities, a process for preparing tautomycetin from the said microorganism, and an immunosuppressant or immunosuppressive pharmaceutical composition comprising tautomycetin as an active ingredient which suppresses interleukin-2 production, CD69 and interleukin-2 receptor(IL-2R) expression on the cell surface, and graft rejection in the organ transplantation. The present inventors isolated a soil microorganism which produces a substance possessing antibiotic and immunosuppressive activities, and identified the said microorganism and substance as a novel Streptomyces sp. and tautomycetin, respectively.
    Type: Application
    Filed: May 17, 1999
    Publication date: August 23, 2001
    Inventors: HYOUNG SIK CHUN, JONG GWAN KIM, HUNG BAE CHANG, SEUNG KEE MOON, HYEOG JIN SON, CHUNG II HONG, JUNG WOO KIM, NAM HYUN LYU