Abstract: Provided are a nanoliposome-microbubble conjugate in which a drug for hair loss treatment such as finasteride, minoxidil, dutasteride, etc. is encapsulated in a nanoliposome and a composition for alleviating or treating hair loss containing the same. Since an orally administered agent such as finasteride, currently useful as a drug for hair loss treatment, causes side effects, drug delivery through scalp application is most desirable, but the drug is not delivered to hair follicle cells through scalp application alone. Since a drug for hair loss treatment useful as an external preparation for skin causes various side effects, the concentration thereof that is used needs to be further lowered. The above nanoliposome-microbubble conjugate is capable of increasing the delivery efficiency of a drug for hair loss treatment at a low concentration, and is thus very effective at treating androgenic alopecia.

Abstract: The present invention relates to a nanoliposome-microbubble conjugate, in which a complex of a Cas9 protein, a guide RNA inhibiting SRD5A2 gene expression and a cationic polymer is encapsulated in a nanoliposome, and to a composition for the amelioration or treatment of hair loss containing the same. Currently, drugs used for the treatment of hair loss cause serious side effects such as loss of libido or erectile dysfunction, and hair loss progresses again when drug treatment is stopped. However, when the nanoliposome-microbubble conjugate of the present invention is used, the expression of SRD5A2 inducing hair loss can be fundamentally suppressed, and the treatment of male hair loss can be performed very effectively.

Abstract: Provided are a nanoliposome-microbubble conjugate in which a drug for hair loss treatment such as finasteride, minoxidil, dutasteride, etc. is encapsulated in a nanoliposome and a composition for alleviating or treating hair loss containing the same. Since an orally administered agent such as finasteride, currently useful as a drug for hair loss treatment, causes side effects, drug delivery through scalp application is most desirable, but the drug is not delivered to hair follicle cells through scalp application alone. Since a drug for hair loss treatment useful as an external preparation for skin causes various side effects, the concentration thereof that is used needs to be further lowered. The above nanoliposome-microbubble conjugate is capable of increasing the delivery efficiency of a drug for hair loss treatment at a low concentration, and is thus very effective at treating androgenic alopecia.

Abstract: The present invention relates to nano-liposome carrier compositions that encapsulate a hybrid of a Cas9 protein and a guide RNA and methods of making and using the same. The nano-liposome carrier compositions have an excellent effect of suppressing expression of target DNA, and thus pharmaceutical compositions including the nano-liposome carrier compositions can be used for treating diseases such as diabetes.

Abstract: A carbon felt heating device is disclosed. The carbon felt heating device includes a carbon felt unit adapted to radiate heat upon supply of power, and power-connecting portions, which are provided at two ends of the carbon felt unit so as to electrically connect the carbon felt unit to a power source, wherein at least some of voids in the carbon felt unit are filled with resin or polymer.

Abstract: The present invention relates to an immunogenic fragment peptide of an EN2 protein or an antibody composition specifically recognizing the same. In the present invention, EN2 protein can be quantified through a method of specifically recognizing the peptide. Also, an antibody prepared using the peptide has vastly superior detection sensitivity compared to existing EN2 protein antibodies and thus can be useful in a diagnostic agent for diagnosing prostate cancer.

Abstract: The present disclosure generally discloses dynamic monitoring and management capabilities for use in wireless communication systems. The dynamic monitoring and management capabilities may be configured to support dynamic monitoring and management within various types of contexts and associated environments. The dynamic monitoring and management capabilities may include feedback collection capabilities, service quality evaluation capabilities, parameter tuning capabilities, or the like, as well as various combinations thereof.

Abstract: The present invention relates to nano-liposome carrier compositions that encapsulate a hybrid of a Cas9 protein and a guide RNA and methods of making and using the same. The nano-liposome carrier compositions have an excellent effect of suppressing expression of target DNA, and thus pharmaceutical compositions including the nano-liposome carrier compositions can be used for treating diseases such as diabetes.

Abstract: The present invention relates to nano-liposome carrier compositions that encapsulate a hybrid of a Cas9 protein and a guide RNA and methods of making and using the same. The nano-liposome carrier compositions have an excellent effect of suppressing expression of target DNA, and thus pharmaceutical compositions including the nano-liposome carrier compositions can be used for treating diseases such as diabetes.

Abstract: A remote attaching and detaching device which includes a camera module to substitute a worker's vision in such an environment where the worker's direct access to the in-cell is extremely limited or impossible. In a remote attaching and detaching device including a camera module for monitoring operating environment of a slave arm of a remote robot working in hazardous environment, the remote attaching and detaching device includes a fixing module fixed to a proximity of a gripper provided on the slave arm, and the camera module is attachable to and detachable from the fixing module, and provides visual in-cell information or situation about surroundings of the gripper.

Abstract: Systems and methods are provided for ranking electronic information based on determined similarities. In one aspect a set of unique features are determined from a collection of electronic objects. A graph is constructed in which electronic object are represented as object nodes and determined features are represented as feature nodes. The object nodes are interconnected by a weighted edge to at least one feature node. Scores for the object nodes and the feature nodes are computed using a determined set of anchor nodes and a determined weighted adjacency matrix. The object nodes and the feature nodes of the graph are ranked and displayed based on the computed scores. In one aspect, the scores and the ranks for the object nodes and the feature nodes are dynamically updated and displayed based on user preferences.

Abstract: The present disclosure generally discloses dynamic monitoring and management capabilities for use in wireless communication systems. The dynamic monitoring and management capabilities may be configured to support dynamic monitoring and management within various types of contexts and associated environments. The dynamic monitoring and management capabilities may include feedback collection capabilities, service quality evaluation capabilities, parameter tuning capabilities, or the like, as well as various combinations thereof.

Abstract: The present disclosure generally discloses dynamic monitoring and management capabilities for use in wireless communication systems. The dynamic monitoring and management capabilities may be configured to support dynamic monitoring and management within various types of contexts and associated environments. The dynamic monitoring and management capabilities may include feedback collection capabilities, service quality evaluation capabilities, parameter tuning capabilities, or the like, as well as various combinations thereof.

Abstract: A power load prediction method includes determining a relationship between power load and temperature during a selected time. A decomposition of the determined relationship is determined. The decomposition indicates a plurality of contributors to the determined power load. A predicted power load is estimated based on the plurality of contributors and a regression model.

Abstract: A system and method for workflow analysis includes an evaluation module executing on a processor that receives execution logs including records of workflow paths traversed. The evaluation module correlates at least one workflow step with a target metric and generates an importance score for the at least one workflow step based on the correlation with the target metric.

Abstract: The present invention provides a digital wireless intercom system including: at least one master base station; at least one remote base station connected to the at least one master base station wiredly through at least one of a local area network, a local area network infrastructure and an internet, the at least one remote base station transmitting and receiving a synchronization signal and a data signal of digital type with the at least one master base station; a plurality of first belt packs within a transmission radius of the at least one master base station, the plurality of first belt packs transmitting and receiving the synchronization signal and the data signal with the at least one master base station wirelessly; and a plurality of second belt packs within a transmission radius of the at least one remote base station, the plurality of second belt packs transmitting and receiving the synchronization signal and the data signal with the at least one remote base station wirelessly, wherein the at least on

Abstract: A wearable robot for assisting muscular strength of the lower extremity of a user: The wearable robot can be worn on user's legs and includes a central securing part, a hip joint part hingably coupled to either side of a lower end of the central securing part, a femur part fastened to the hip joint part and having rigidity, a knee part including an outer frame and a knee assistant, and a drive unit fastened to one of the hip joint part and the knee joint part to allow operation of the joint part. The outer frame includes an upper side outer frame fastened to a lower end of the femur part and a lower side outer frame fastened to the upper side outer frame by a rotatable knee joint part Both the upper side outer frame and the lower side outer frame are fastened to the knee assistant worn by the user.

Abstract: A remote attaching and detaching device is provided, which includes a camera module to substitute a worker's vision in such an environment where the worker's direct access to the in-cell is extremely limited or impossible. In a remote attaching and detaching device including a camera module for monitoring operating environment of a slave arm of a remote robot working in hazardous environment, the remote attaching and detaching device includes a fixing module fixed to a proximity of a gripper provided on the slave arm, and the camera module is attachable to and detachable from the fixing module, and provides visual in-cell information or situation about surroundings of the gripper.

Abstract: The present invention provides a digital wireless intercom system including: at least one master base station; at least one remote base station connected to the at least one master base station wiredly through at least one of a local area network, a local area network infrastructure and an internet, the at least one remote base station transmitting and receiving a synchronization signal and a data signal of digital type with the at least one master base station; a plurality of first belt packs within a transmission radius of the at least one master base station, the plurality of first belt packs transmitting and receiving the synchronization signal and the data signal with the at least one master base station wirelessly; and a plurality of second belt packs within a transmission radius of the at least one remote base station, the plurality of second belt packs transmitting and receiving the synchronization signal and the data signal with the at least one remote base station wirelessly, wherein the at least on

Abstract: A wearable robot for assisting muscular strength of the lower extremity of a user: The wearable robot can be worn on user's legs and includes a central securing part, a hip joint part hingably coupled to either side of a lower end of the central securing part, a femur part fastened to the hip joint part and having rigidity, a knee part including an outer frame and a knee assistant, and a drive unit fastened to one of the hip joint part and the knee joint part to allow operation of the joint part. The outer frame includes an upper side outer frame fastened to a lower end of the femur part and a lower side outer frame fastened to the upper side outer frame by a rotatable knee joint part Both the upper side outer frame and the lower side outer frame are fastened to the knee assistant worn by the user.