Patents by Inventor NaMi McCarty

NaMi McCarty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Regulation of mink in thymocytes and T lymphocytes
    Patent number: 8197817
    Abstract: The invention relates to compositions and methods used to assess and alter the expression and activity of MINK in cells of the immune system, particularly thymocytes and T lymphocytes. The methods and compositions are used in a variety of clinical applications including vaccination, treatment of cancer, infectious disease, allergy, and transplantation. Screening methods are provided to identify inhibitors of MINK and susceptibility to effects of under- or over-expression of MINK.
    Type: Grant
    Filed: December 16, 2005
    Date of Patent: June 12, 2012
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Harvey Cantor, Nami McCarty
  • Regulation of Mink in Thymocytes and T Lymphocytes
    Publication number: 20080248054
    Abstract: The invention relates to compositions and methods used to assess and alter the expression and activity of MINK in cells of the immune system, particularly thymocytes and T lymphocytes. The methods and compositions are used in a variety of clinical applications including vaccination, treatment of cancer, infectious disease, allergy, and transplantation. Screening methods are provided to identify inhibitors of MINK and susceptibility to effects of under- or over-expression of MINK.
    Type: Application
    Filed: December 16, 2005
    Publication date: October 9, 2008
    Applicant: Dana-Farber Cancer Institute
    Inventors: Harvey Cantor, Nami McCarty
  • Monoclonal antibodies specific for neoplasia-specific NADH:disulfide reductase
    Patent number: 7053188
    Abstract: Compositions and methods for diagnosis of neoplastic tissue are described. Monoclonal antibodies which specifically recognize the tumor cell specific NADH:protein thiol reductase and the hybridoma cell lines which produce them are provided. Also provided are diagnostic and immunohistological assays for the identification of cells that are neoplastic.
    Type: Grant
    Filed: February 24, 2003
    Date of Patent: May 30, 2006
    Assignee: Purdue Research Foundation
    Inventors: D. James Morré, NaMi McCarty, Dorothy Morré, Pin-Ju Chueh
  • Monoclonal antibodies specific for neoplasia-specific NADH:disulfide reductase
    Publication number: 20030170757
    Abstract: Compositions and methods for diagnosis of neoplastic tissue are described. Monoclonal antibodies which specifically recognize the tumor cell specific NADH:protein thiol reductase and the hybridoma cell lines which produce them are provided. Also provided are diagnostic and immunohistological assays for the identification of cells that are neoplastic. Because the antibodies specifically prevent the growth of cancer cells, induce apoptotic cell death of cancer cells, and are without effect on normal cells, the described monoclonal antibodies are useful for inhibiting cancer cell growth and for treating a neoplastic condition.
    Type: Application
    Filed: February 24, 2003
    Publication date: September 11, 2003
    Inventors: D. James Morre, NaMi McCarty, Dorothy Morre, Pin-Ju Chueh