Patents by Inventor Nami Sugita
Nami Sugita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9421284Abstract: A reaction container in which to mix a first chemical compound with a second chemical compound has a main body and a lid member formed oppositely on a top face side of the main body; a flow channel on the top face of the main body; and a labeling agent solidification section at an intermediate section of the flow channel to remove a solvent in a solution of the second chemical compound and solidify the second chemical compound. First and second chemical compound supply sections and a mixture discharge section are formed on the upstream and downstream sides of the labeling agent solidification section, respectively. The reactor is provided with a liquid sending unit to supply the first and second chemical compounds and reciprocally send a solution of the first chemical compound to an upper part of the second chemical compound solidified at the solidification section.Type: GrantFiled: December 26, 2012Date of Patent: August 23, 2016Assignee: HITACHI, LTD.Inventors: Nami Sugita, Naomi Manri, Wataru Takeuchi, Yuichi Morimoto, Hiroko Hanzawa
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Publication number: 20160215224Abstract: As one aspect of the present invention, a chemical substance production system includes a first liquid reaction system that generates a first chemical substance, a second liquid reaction system that generates a second chemical substance, and a first membrane that is provided between the first liquid reaction system and the second liquid reaction system, wherein the second liquid reaction system causes a chemical reaction of the first chemical substance transferred from the first liquid reaction system to the second liquid reaction system through the first membrane, thereby generating the second chemical substance. According to this, a fuel production system that efficiently removes contaminants occurring in an extraction step when producing fuel derived from an alga or the like is provided.Type: ApplicationFiled: August 28, 2013Publication date: July 28, 2016Inventors: Hiroko TADA, Nami SUGITA, Norihito KUNO
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Publication number: 20150335769Abstract: A reaction container in which to mix a first chemical compound with a second chemical compound has a main body and a lid member formed oppositely on a top face side of the main body; a flow channel on the top face of the main body; and a labeling agent solidification section at an intermediate section of the flow channel to remove a solvent in a solution of the second chemical compound and solidify the second chemical compound. First and second chemical compound supply sections and a mixture discharge section are formed on the upstream and downstream sides of the labeling agent solidification section, respectively. The reactor is provided with a liquid sending unit to supply the first and second chemical compounds and reciprocally send a solution of the first chemical compound to an upper part of the second chemical compound solidified at the solidification section.Type: ApplicationFiled: December 26, 2012Publication date: November 26, 2015Inventors: Nami SUGITA, Naomi MANRI, Wataru TAKEUCHI, Yuichi MORIMOTO, Hiroko HANZAWA
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Patent number: 8323620Abstract: An ultrasound contrast agent composed of at least one kind of low-boiling water-insoluble substance (with a boiling point lower than 37° C.) and at least one kind of high-boiling water-insoluble substance (with a boiling point higher than 37° C.). The former vaporizes to absorb ultrasonic energy upon application of ultrasound, thereby causing the latter to vaporize secondarily, with the resulting bubbles producing an echo image. It is less liable to bumping and hence safe.Type: GrantFiled: August 4, 2005Date of Patent: December 4, 2012Assignee: Hitachi Medical CorporationInventors: Kenichi Kawabata, Nami Sugita, Shin-ichiro Umemura
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Patent number: 7993581Abstract: The present invention provides an immunoassay technique which enables efficient detection of antigen-antibody reaction with high sensitivity by a magnetic method using magnetic particles and a SQUID magnetic sensor or sensors. A system based on the technique includes a disk-shaped sample holder which holds on a circle a plurality of sample containers for accommodating marked samples, resulting from marking of samples with magnetic particles by antigen-antibody reaction; rotating means for rotating the holder around its central shaft; magnetizing means for magnetizing the marked samples outside a magnetic shield; and a magnetic sensor for detecting, within the magnetic shield, magnetic fields generated from the marked samples which have been magnetized.Type: GrantFiled: December 8, 2004Date of Patent: August 9, 2011Assignee: Hitachi, Ltd.Inventors: Yusuke Seki, Akira Tsukamoto, Daisuke Suzuki, Masahiro Yamaoka, Nami Sugita, Akihiko Kandori, Kazuo Saitoh
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Patent number: 7824336Abstract: An ultrasonic apparatus for diagnosis and therapy is provided with plural ultrasound probes for generating ultrasound waves for phase shift, diagnosis, and therapy. A first control part causes phase shift in a nano droplet ultrasound contrast agent, while a second control part detects the phase shift of the nano droplet ultrasound contrast agent using ultrasound echo detected by an echo detection device. A difference calculation device calculates a difference of the detected phase shift over time, and a positioning device determines a target position where the difference is produced. A third control part is also provided for exposing a decided target area to the ultrasound waves for therapy.Type: GrantFiled: January 23, 2006Date of Patent: November 2, 2010Assignee: Hitachi, Ltd.Inventors: Kenichi Kawabata, Nami Sugita, Shinichiro Umemura
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Patent number: 7780598Abstract: In a sonodynamic treatment apparatus including: a first ultrasound radiating unit for radiating diagnostic ultrasound; a second ultrasound radiating unit for radiating treatment ultrasound; an echo detection unit for detecting an ultrasound echo; a diagnostic controller for radiating the diagnostic ultrasound with the first ultrasound radiating unit and detecting the ultrasound echo corresponding the diagnostic ultrasound; an echographic controller for processing an echographic image on the basis of the detected ultrasound echo; and a treatment controller for radiating the treatment ultrasound with the second ultrasound radiating unit, radiation of the treatment ultrasound with the second ultrasound radiating unit is controlled to have a predetermined exposure duration and a predetermined pause duration of the treatment ultrasound, and the echographic image is generated on the basis of the ultrasound echo during the pause duration of the treatment ultrasound exposure with the diagnostic image generator.Type: GrantFiled: June 29, 2006Date of Patent: August 24, 2010Assignee: Hitachi, Ltd.Inventors: Nami Sugita, Ken-ichi Kawabata, Takashi Azuma, Shin-ichiro Umemura
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Publication number: 20090054722Abstract: The present invention provides drug carriers having high heating efficiency by high-frequency dielectric heating in a state of being selectively accumulated in a target site. The drug carriers each consist of a drug, magnetic fine particles, and a shell containing the drug and the magnetic fine particles. The shell has an outer diameter in a range from 10 nm to 200 nm. The magnetic fine particles having an average particle diameter of d has a standard deviation ? of particle diameter distribution satisfying 0.8d>?>0.4d. The magnetic fine particles contained in the individual drug carriers generate hysteresis heat due to high-frequency dielectric heating by irradiation of a high-frequency magnetic field.Type: ApplicationFiled: August 6, 2008Publication date: February 26, 2009Inventors: Ryoko Sugano, Nami Sugita, Teruo Kohashi, Keiji Takata, Chiharu Mitsumata, Shigeo Fujii
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Publication number: 20080311046Abstract: An ultrasound contrast agent composed of at least one kind of low-boiling water-insoluble substance (with a boiling point lower than 37° C.) and at least one kind of high-boiling water-insoluble substance (with a boiling point higher than 37° C.). The former vaporizes to absorb ultrasonic energy upon application of ultrasound, thereby causing the latter to vaporize secondarily, with the resulting bubbles producing an echo image. It is less liable to bumping and hence safe.Type: ApplicationFiled: August 4, 2005Publication date: December 18, 2008Inventors: Kenichi Kawabata, Nami Sugita, Shin-ichiro Umemura
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Publication number: 20070038099Abstract: In a sonodynamic treatment apparatus including: a first ultrasound radiating unit for radiating diagnostic ultrasound; a second ultrasound radiating unit for radiating treatment ultrasound; an echo detection unit for detecting an ultrasound echo; a diagnostic controller for radiating the diagnostic ultrasound with the first ultrasound radiating unit and detecting the ultrasound echo corresponding the diagnostic ultrasound; an echographic controller for processing an echographic image on the basis of the detected ultrasound echo; and a treatment controller for radiating the treatment ultrasound with the second ultrasound radiating unit, radiation of the treatment ultrasound with the second ultrasound radiating unit is controlled to have a predetermined exposure duration and a predetermined pause duration of the treatment ultrasound, and the echographic image is generated on the basis of the ultrasound echo during the pause duration of the treatment ultrasound exposure with the diagnostic image generator.Type: ApplicationFiled: June 29, 2006Publication date: February 15, 2007Inventors: Nami Sugita, Ken-ichi Kawabata, Takashi Azuma, Shin-ichiro Umemura
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Publication number: 20070016042Abstract: The ultrasonic apparatus for a diagnosis and therapy includes: a first ultrasound probe, a second ultrasound probe, and an ultrasound exposure apparatus for exposing ultrasounds for a phase shift, diagnosis, and therapy, respectively; an echo detection device for detecting an ultrasound echo; control parts for the phase shift for causing the shift in an ultrasound contrast agent by exposing the ultrasound for the shift through the first device, and for the diagnosis for detecting the shift of the agent, using the echo detected by the detection device, corresponding to an exposure of the ultrasound for the diagnosis by the second device; a difference calculation device for calculating a difference over time of the shift detected by the control part for the diagnosis; a device for positioning for deciding a target position where the difference is produced; and a control part for the therapy for exposing the ultrasound for the therapy to the decided target position through the exposure apparatus.Type: ApplicationFiled: January 23, 2006Publication date: January 18, 2007Inventors: Kenichi Kawabata, Nami Sugita, Shinichiro Umemura
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Patent number: 7125387Abstract: According to the invention, an ultrasonic apparatus for therapeutical use suitable for remedy by the irradiation of an ultrasonic wave low in the degree of convergence using medicine that stays in a disease region, reduces the threshold of cavitation caused by an ultrasonic wave and secondarily generates active oxygen by the acoustic cavitation caused by the ultrasonic wave is provided. The ultrasonic apparatus for therapeutical use is provided with a belt wearable in a position (on the abdomen of a patient) that surrounds a diseased part and unit ultrasonic radiators can be mounted in an arbitrary position of the belt.Type: GrantFiled: February 20, 2003Date of Patent: October 24, 2006Assignee: Hitachi, Ltd.Inventors: Kenichi Kawabata, Nami Sugita, Shinichiro Umemura, Takashi Azuma
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Publication number: 20050202572Abstract: The present invention provides an immunoassay technique which enables efficient detection of antigen-antibody reaction with high sensitivity by a magnetic method using magnetic particles and a SQUID magnetic sensor or sensors. A system based on the technique includes a disk-shaped sample holder which holds on a circle a plurality of sample containers for accommodating marked samples, resulting from marking of samples with magnetic particles by antigen-antibody reaction; rotating means for rotating the holder around its central shaft; magnetizing means for magnetizing the marked samples outside a magnetic shield; and a magnetic sensor for detecting, within the magnetic shield, magnetic fields generated from the marked samples which have been magnetized.Type: ApplicationFiled: December 8, 2004Publication date: September 15, 2005Inventors: Yasuke Seki, Akira Tsukamoto, Daisuke Suzuki, Masahiro Yamaoka, Nami Sugita, Akihiko Kandori, Kazuo Saitoh
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Publication number: 20040044298Abstract: According to the invention, an ultrasonic apparatus for therapeutical use suitable for remedy by the irradiation of an ultrasonic wave low in the degree of convergence using medicine that stays in a disease region, reduces the threshold of cavitation caused by an ultrasonic wave and secondarily generates active oxygen by the acoustic cavitation caused by the ultrasonic wave is provided. The ultrasonic apparatus for therapeutical use is provided with a belt wearable in a position (on the abdomen of a patient) that surrounds a diseased part and unit ultrasonic radiators can be mounted in an arbitrary position of the belt.Type: ApplicationFiled: February 20, 2003Publication date: March 4, 2004Inventors: Kenichi Kawabata, Nami Sugita, Shinichiro Umemura, Takashi Azuma
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Patent number: 6572839Abstract: A sensitizer for tumor treatment has a structure such that a lipophilic group and a hydrophilic group are bound to one and the same carbon atom in a compound containing a xanthene dye structure. It is important that the lipophilic group and hydrophilic group are bound to one and the same carbon atom; if they are separated from each other, no sufficient effect is obtained. Thus, the sensitizer possesses both lipophilicity and hydrophilicity. This sensitizer has a function of promoting acoustic cavitation and a function of revealing an antitumor effect and is an agent highly accumulable in tumor tissues. Thus, this sensitizer is highly selective for tumor tissues and enables the treatment of malignant tumor using ultrasound.Type: GrantFiled: March 9, 2001Date of Patent: June 3, 2003Assignee: Hitachi, Ltd.Inventors: Nami Sugita, Kenichi Kawabata, Shinichiro Umemura, Kazuaki Sasaki, Isao Sakata
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Publication number: 20010041163Abstract: A sensitizer for tumor treatment has a structure such that a lipophilic group and a hydrophilic group are bound to one and the same carbon atom in a compound containing a xanthene dye structure. It is important that the lipophilic group and hydrophilic group are bound to one and the same carbon atom; if they are separated from each other, no sufficient effect is obtained. Thus, the sensitizer possesses both lipophilicity and hydrophilicity. This sensitizer has a function of promoting acoustic cavitation and a function of revealing an antitumor effect and is an agent highly accumulable in tumor tissues. Thus, this sensitizer is highly selective for tumor tissues and enables the treatment of malignant tumor using ultrasound.Type: ApplicationFiled: March 9, 2001Publication date: November 15, 2001Inventors: Nami Sugita, Kenichi Kawabata, Shinichiro Umemura, Kazuaki Sasaki, Isao Sakata