Patents by Inventor Naming Zhou

Naming Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel peptide antagonist of CXCR4 derived from the N-terminus of the viral chemokine vMIP-II
    Publication number: 20030220482
    Abstract: The viral Macrophage Inflammatory Protein-II (vMIP-II) is a chemokine that interacts with the CC and CXC chemokine receptors, including the CCR5 and CXCR4 chemokine receptors. CCR5 and CXCR4 are the principal coreceptors required for cell entry of human immunodeficiency virus type 1 (HIV-1). The present invention describes a peptide fragment of the vMIP-II that prevents the HIV-1 virus from interacting with the coreceptor CXCR4, thereby preventing viral infection of that cell. These peptide fragments will serve as lead compounds for the development of therapeutic agents against HIV-1 infections.
    Type: Application
    Filed: February 1, 2001
    Publication date: November 27, 2003
    Inventors: Ziwei Huang, Jiansong Luo, Zhaowen Luo, Naming Zhou