Abstract: A semiconductor device includes a substrate, an interconnect structure, and conductive vias. The substrate has a first side, a second side and a sidewall connecting the first side and the second side, wherein the sidewall includes a first planar sidewall of a first portion of the substrate, a second planar sidewall of a second portion of the substrate and a curved sidewall of a third portion of the substrate, where the first planar sidewall is connected to the second planar sidewall through the curved sidewall. The interconnect structure is located on the first side of the substrate, where a sidewall of the interconnect structure is offset from the second planar sidewall. The conductive vias are located on the interconnect structure, where the interconnect structure is located between the conductive vias and the substrate.

Abstract: A method for identifying video signal source is provided. The method includes the following steps. A first identification code is assigned to a first transmitter device by a receiver control unit of a receiver device. A first video data is transmitted by the first transmitter device. The first video data and a first identification image corresponding to the first identification code are combined as a first combined video data by the receiver control unit. The first combined video data is outputted to a display device by the receiver control unit.

Abstract: A portable electronic device including a first body, a second body, and a hinge mechanism is provided. The second body is connected to the first body through the hinge mechanism, and the hinge mechanism has a basis axis located at the first body and a rotation axis located at a lower end of the second body. When the second body rotates with respect to the first body, the rotation axis slides along an arc shaped path with respect to the basis axis to increase or decrease a distance between the rotation axis and the basis axis and increase or decrease a distance between the lower end of the second body and a back end of the first body.

Abstract: Disclosed herein is a method of providing a metabololipidomic profile and SPM signature on the progress of the innate host defense response following blood clotting. The method can include the step of taking one or more measurements in a patient's blood sample, wherein the sample is obtained during the time-course of clotting or coagulation or following clotting or coagulation, of pro-thrombotic and pro-inflammatory mediators (eicosanoids) and specialized pro-resolving mediators SPMs. From these measurements, a personalized metabololipidomic profile can be obtained. By comparing the measurement to that taken from normal or reference blood, a comparison profile can be developed. The profile comparison profile can then be used to make a medical or therapeutic decision.

Abstract: New host-protective molecules containing conjugated triene and diene double bonds with each carrying a 13-carbon position alcohol and were derived from n-3 docosapentaenoic acid (DPA, C22:5) were produced in neutrophil-endothelial co-cultures, and they are present in human and mouse tissues after sterile inflammation or infection. These compounds, termed 13-series resolvins (RvT), demonstrated potent protective actions increasing mice survival during Escherichia coli infections. Their biosynthesis during neutrophil-endothelial cell interactions was initiated by endothelial cyclooxygenase-2 (COX-2) and increased by atorvastatin via S-nitrosylation of COX-2. Atorvastatin and RvT were additive in E. coli infections in mice where they accelerated resolution of inflammation and increased survival >60%. Results documented novel host protective molecules in bacterial infections, namely RvT, derived from n-3 DPA via transcellular biosynthesis and increased by atorvastatin.

Abstract: A wheeled carrying apparatus includes a handle frame rotatable relative to a standing frame between a first and a second position, a wheel mount pivotally connected with the standing frame, a wheel mount latch adapted to lock and unlock the wheel mount with respect to the standing frame, an actuating assembly coupling the wheel mount latch to the handle frame so that the wheel mount latch is movable to engage and disengage the wheel mount in response to a rotation of the handle frame, and a release mechanism including an operating part that is coupled to the actuating assembly via a cable assembly. The cable assembly includes a flexible part configured to stretch or loosen as the handle frame rotates between the two positions, the operating part being operable to cause the wheel mount latch to disengage from the wheel mount when the handle frame is in the first position.

Abstract: A wheeled carrying apparatus includes a handle frame rotatable relative to a standing frame between a first and a second position, a wheel mount pivotally connected with the standing frame, a wheel mount latch adapted to engage and lock the wheel mount with respect to the standing frame and to disengage and unlock the wheel mount so that it is rotatable for changing orientation of a wheel axis, a link actuator coupled to the wheel mount latch via a linking part that is movable as the handle frame rotates for causing the wheel mount latch to engage or disengage the wheel mount, and a release mechanism including a cable assembly that couples an operating part carried with the handle frame to the wheel mount latch, the operating part being operable to cause the wheel mount latch to disengage the wheel mount in the first position of the handle frame.

Abstract: The invention relates to (S)-6-((1 R,2E,4E,8E,10S)-11-(4-fluorophenoxy)-1,10-dihydroxyundeca-2,4,8-trien-6-yn-1-yl)-1,4-dioxan-2-one (compound (1)), which is a lactone-containing analog of lipoxin A4 (LXA4). In particular, the invention features pharmaceutical compositions including compound (1) and the use of compound (1) for the treatment of a disorder (e.g., a fibrotic disorder or an inflammatory disorder, such as an autoimmune disorder) in a subject in need thereof.

Abstract: A family of bioactive compounds identified in self-resolving inflammatory exudates is disclosed. The compounds give UV chromophores characteristic of a conjugated triene double bond system coupled to an auxochrome allylic to the triene. Further elucidation of the compounds reveals that they have a resolvin backbone conjugated to a peptide or amino acid moiety via an auxochrome. In some embodiments the auxochrome is sulfur. However, the auxochrome may be NH, CH2 or O. The compounds have potent bioactivity, in vitro, and, in vivo, including promoting resolution of infection, stimulating macrophage phagocytosis of bacteria; protecting tissues from neutrophil mediated damage, promoting tissue repair and regeneration and preventing or limiting second organ reflow/reperfusion damage.

Abstract: A family of bioactive compounds identified in self-resolving inflammatory exudates is disclosed. The compounds give UV chromophores characteristics of a conjugated triene double bond system coupled to an auxochrome allylic to the triene. Further elucidation of the compounds reveals that they have an oxylipin backbone conjugated to a peptide or amino acid moiety via an auxochrome. In some embodiments the auxochrome is sulfur. However, the auxochrome may be NH, CH2 or O. The compounds have potent bioactivity, in vitro, and, in vivo, including promoting resolution of infection, stimulating macrophage phagocytosis of bacteria; protecting tissues from neutrophil mediated damage, promoting tissue repair and regeneration and preventing or limiting second organ reflow/reperfusion damage.

Abstract: A wheeled carrying apparatus includes a handle frame rotatable relative to a standing frame between a first and a second position, a wheel mount pivotally connected with the standing frame, a wheel mount latch adapted to engage and lock the wheel mount with respect to the standing frame and to disengage and unlock the wheel mount so that it is rotatable for changing orientation of a wheel axis, a link actuator coupled to the wheel mount latch via a linking part that is movable as the handle frame rotates for causing the wheel mount latch to engage or disengage the wheel mount, and a release mechanism including a cable assembly that couples an operating part carried with the handle frame to the wheel mount latch, the operating part being operable to cause the wheel mount latch to disengage the wheel mount in the first position of the handle frame.

Abstract: New host-protective molecules containing conjugated triene and diene double bonds with each carrying a 13-carbon position alcohol and were derived from n-3 docosapentaenoic acid (DPA, C22:5) were produced in neutrophil-endothelial co-cultures, and they are present in human and mouse tissues after sterile inflammation or infection. These compounds, termed 13-series resolvins (RvT), demonstrated potent protective actions increasing mice survival during Escherichia coli infections. Their biosynthesis during neutrophil-endothelial cell interactions was initiated by endothelial cyclooxygenase-2 (COX-2) and increased by atorvastatin via S-nitrosylation of COX-2. Atorvastatin and RvT were additive in E. coli infections in mice where they accelerated resolution of inflammation and increased survival >60%. Results documented novel host protective molecules in bacterial infections, namely RvT, derived from n-3 DPA via transcellular biosynthesis and increased by atorvastatin.

Abstract: Disclosed herein is a method of providing a metabololipidomic profile and SPM signature on the progress of the innate host defense response following blood clotting. The method can include the step of taking one or more measurements in a patient's blood sample, wherein the sample is obtained during the time-course of clotting or coagulation or following clotting or coagulation, of pro-thrombotic and pro-inflammatory mediators (eicosanoids) and specialized pro-resolving mediators SPMs. From these measurements, a personalized metabololipidomic profile can be obtained. By comparing the measurement to that taken from normal or reference blood, a comparison profile can be developed. The profile comparison profile can then be used to make a medical or therapeutic decision.

Abstract: The connecting module is converted to a third state from a first state through a second state. The connecting module includes a fourth part, a first part, a second part and a third part, which are sequentially disposed in an axial direction. The first part is fixed to the third part. From the first state to the third state, the fourth part rotates together with the first part. From the first state to the second state, the first part rotates with respect to the second part, and the second part moves with respect to the third part in the axial direction.

Abstract: Endogenous mechanisms leading to host protection and resolution of infections without immunosuppression are of wide interest. Here we elucidated the structures of four new host-protective molecules produced in neutrophil-endothelial co-cultures, and present in human and mouse tissues after sterile inflammation or infection. These bioactive molecules contained conjugated triene and diene double bonds with each carrying a 13-carbon position alcohol and were derived from n-3 docosapentaenoic acid (DPA, C22:5). These compounds, termed 13-series resolvins (RvT), demonstrated potent protective actions increasing mice survival during Escherichia coli infections. RvT also regulated human and mouse phagocyte responses stimulating bacterial phagocytosis and regulating inflammasome components. Their biosynthesis during neutrophil-endothelial cell interactions was initiated by endothelial cyclooxygenase-2 (COX-2) and increased by atorvastatin via S-nitrosylation of COX-2.

Abstract: A connecting module and a system using the same are provided. The connecting module is converted to a third state from a first state through a second state. The connecting module includes a fourth part, a first part, a second part and a third part, which are sequentially disposed in an axial direction. The first part is fixed to the third part. From the first state to the third state, the fourth part rotates together with the first part. From the first state to the second state, the first part rotates with respect to the second part, and the second part moves with respect to the third part in the axial direction.

Abstract: A lens structure is provided. The lens structure comprises a first barrel, a second barrel and a third barrel. The first barrel has a first groove and comprises a first pin. The second barrel has a second groove and comprises a second pin. The third barrel has a third groove. The first barrel is rotatably disposed outside of the third barrel. The second barrel is disposed in the inside of the third barrel. The second pin of the second barrel slides along the third groove of the third barrel and the first groove of the first barrel. The first pin of the first barrel slides along the second groove of the second barrel.

Abstract: A parallel multiplex test system is disclosed. The parallel multiplex test system is used for testing N devices under test (DUTs) in the N isolation boxes via N test signals through N test channels. The parallel multiplex test system comprises a central processing unit and N function-test modules, wherein N is a positive integer greater than one. The parallel multiplex test system requests the function-test modules to take the function-tests for N DUTs according to the test items which have not been tested, so that different function-tests are taken for all of the DUTs simultaneously through different channels.

Abstract: The lens structure comprises a first barrel, a second barrel and a third barrel. The second barrel has a first guiding groove and comprises a first pin. The third barrel has a second guiding groove and a second pin. The first barrel is rotatably disposed outside of the third barrel, and the second barrel is translatably but not rotatably disposed inside of the third barrel. The first pin of the second barrel slides along the second guiding groove of the third barrel, and the second pin of the third barrel slides along the first guiding groove of the second barrel.

Abstract: An auto focus module of an image capture device is provided. The auto focus module comprises at least one gear, a nut, a lead screw and a driver. The gear has at least one first extension and a first through hole. The nut has at least one second extension and a second through hole. The lead screw penetrates the first through hole and the second through hole. The driver drives the lead screw and the gear so that the lead screw and the gear move relatively along the axis of the lead screw. The nut and the gear terminate approaching toward each other after the first extension and the second extension lean against each other.