Patents by Inventor Nan-Fu Chiu

Nan-Fu Chiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10815259
    Abstract: A method of synthesizing carboxyl-modified molybdenum disulfide comprises the steps of a) preparing a molybdenum disulfide solution; b) adding hydrogen bromide (HBr) to the molybdenum disulfide solution, followed by blending the mixture; and c) adding oxalic acid (OA) to the molybdenum disulfide solution, followed by blending the mixture. The molybdenum disulfide synthesized by the method is applicable to a biosensing chip. The carboxyl-modified molybdenum disulfide effectively enhances sensitivity of a detection device having the biosensing chip.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: October 27, 2020
    Assignee: NATIONAL TAIWAN NORMAL UNIVERSITY
    Inventors: Nan-Fu Chiu, Ting-Li Lin
  • Patent number: 10634613
    Abstract: A molybdenum disulfide-containing biosensing chip includes a transparent substrate; a metal layer disposed on the transparent substrate; and a molybdenum disulfide layer disposed on the metal layer; wherein the molybdenum disulfide layer is carboxyl (—COOH)-modified. The carboxyl (—COOH)-modified molybdenum disulfide layer effectively enhances sensitivity of a detection device having the biosensing chip. The biosensing chip is applicable to detection of various biological molecules.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: April 28, 2020
    Assignee: NATIONAL TAIWAN NORMAL UNIVERSITY
    Inventors: Nan-Fu Chiu, Ting-Li Lin
  • Publication number: 20190352319
    Abstract: A method of synthesizing carboxyl-modified molybdenum disulfide comprises the steps of a) preparing a molybdenum disulfide solution; b) adding hydrogen bromide (HBr) to the molybdenum disulfide solution, followed by blending the mixture; and c) adding oxalic acid (OA) to the molybdenum disulfide solution, followed by blending the mixture. The molybdenum disulfide synthesized by the method is applicable to a biosensing chip. The carboxyl-modified molybdenum disulfide effectively enhances sensitivity of a detection device having the biosensing chip.
    Type: Application
    Filed: April 26, 2018
    Publication date: November 21, 2019
    Applicant: NATIONAL TAIWAN NORMAL UNIVERSITY
    Inventors: NAN-FU CHIU, TING-LI LIN
  • Publication number: 20190219504
    Abstract: A molybdenum disulfide-containing biosensing chip includes a transparent substrate; a metal layer disposed on the transparent substrate; and a molybdenum disulfide layer disposed on the metal layer; wherein the molybdenum disulfide layer is carboxyl (—COOH)-modified. The carboxyl (—COOH)-modified molybdenum disulfide layer effectively enhances sensitivity of a detection device having the biosensing chip. The biosensing chip is applicable to detection of various biological molecules.
    Type: Application
    Filed: March 29, 2018
    Publication date: July 18, 2019
    Applicant: NATIONAL TAIWAN NORMAL UNIVERSITY
    Inventors: NAN-FU CHIU, TING-LI LIN
  • Publication number: 20190212263
    Abstract: A graphene-containing biosensing chip includes a transparent substrate; a metal layer disposed on the transparent substrate; and a graphene layer disposed on the metal layer; wherein the graphene layer is amino (—NH2)-modified. The amino (—NH2)-modified graphene layer effectively enhances sensitivity of a detection device having the biosensing chip. The biosensing chip is applicable to detection of various biological molecules.
    Type: Application
    Filed: March 31, 2018
    Publication date: July 11, 2019
    Applicant: NATIONAL TAIWAN NORMAL UNIVERSITY
    Inventors: NAN-FU CHIU, Chia-Tzu KUO
  • Publication number: 20100274101
    Abstract: A MEMS wireless monitoring bio-diagnosis system includes an implantable biosensor system chip, a surface transmitter and an external monitor center. The implantable biosensor system chip contains a biosensor for a cardio-vascular indicator and a wireless transmitter to deliver detected bio-signal data. With the MEMS wireless monitoring bio-diagnosis system, the bio-signal data can be monitored effectively and transmitted to a remote medical unit.
    Type: Application
    Filed: September 10, 2009
    Publication date: October 28, 2010
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: Chii-Wann Lin, Kuang-Chong Wu, Chih-Kung Lee, Shi-Ming Lin, Shih-Yuan Lee, Fu-Shan Jaw, Chern-Lin Chen, U Lei, Long-Sun Huang, Shey-Shi Lu, Phone Lin, Jia-Yush Yen, Yao-Joe Yang, Lung-Jieh Yang, Wen-Pin Shih, Nan-Fu Chiu
  • Patent number: 7820372
    Abstract: The present invention relates to a dual-band micro-planar inverted F antenna (MPIFA), which is made based on a new type of printed circuit board (PCB), and its identification method to all different biomolecular concentration. This device works under 3 GHz and 7 GHz microwave frequency bands, and can predict the relationship for different absorbed biomolecular concentrations versus frequencies with the impedance value, dB(S(1,1)) parameter, and the variance of phase versus the frequency obtained from the measurement.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: October 26, 2010
    Assignee: National Taiwan University
    Inventors: Chii-Wann Lin, Nan-Fu Chiu, Chih-Kung Lee, Kuang-Chong Wu
  • Patent number: 7671995
    Abstract: Surface plasmon resonance (SPR) sensing technique which provides high specificity and accuracy has been an important method for molecular sensing technology. In the past, in order to affix 45 nm gold film onto glass or silicon substrate, several nanometers of chromium (Cr) or titanium (Ti) has been used as adhesive layer for the attachment of Au film. However, the existence of Cr or Ti thin film deteriorates the performance of SPR sensor due to their characteristic optical absorption. Our experimental results have confirmed the uses of conducting metal oxide, specifically, ITO and Zinc Oxide (ZnO) can be used to replace Cr or Ti for better performance in terms of SPR resonant properties (resonant angle and HMBW) and sensitivity enhancement for 3 to 15 times than traditional ones. It would contribute significantly to the SPR applications in both biosensors and gas sensors.
    Type: Grant
    Filed: March 14, 2008
    Date of Patent: March 2, 2010
    Assignee: National Taiwan University
    Inventors: Chii-Wann Lin, Nan-Fu Chiu, Wei-Yi Feng, Chia-Chen Chang, Kuo-Chuan Ho, Chih-Kung Lee, Kuang-Chong Wu
  • Publication number: 20090161110
    Abstract: Surface plasmon resonance (SPR) sensing technique which provides high specificity and accuracy has been an important method for molecular sensing technology. In the past, in order to affix 45 nm gold film onto glass or silicon substrate, several nanometers of chromium (Cr) or titanium (Ti) has been used as adhesive layer for the attachment of Au film. However, the existence of Cr or Ti thin film deteriorates the performance of SPR sensor due to their characteristic optical absorption. Our experimental results have confirmed the uses of conducting metal oxide, specifically, ITO and Zinc Oxide (ZnO) can be used to replace Cr or Ti for better performance in terms of SPR resonant properties (resonant angle and HMBW) and sensitivity enhancement for 3 to 15 times than traditional ones. It would contribute significantly to the SPR applications in both biosensors and gas sensors.
    Type: Application
    Filed: March 14, 2008
    Publication date: June 25, 2009
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: CHII-WANN LIN, NAN-FU CHIU, WEI-YI FENG, CHIA-CHEN CHANG, KUO-CHUAN HO, CHIH-KUNG LEE, KUANG-CHONG WU
  • Publication number: 20090107216
    Abstract: The present invention relates to a dual-band micro-planar inverted F antenna (MPIFA), which is made based on a new type of printed circuit board (PCB), and its identification method to all different biomolecular concentration. This device works under 3 GHz and 7 GHz microwave frequency bands, and can predict the relationship for different absorbed biomolecular concentrations versus frequencies with the impedance value, dB(S(1,1)) parameter, and the variance of phase versus the frequency obtained from the measurement.
    Type: Application
    Filed: February 5, 2008
    Publication date: April 30, 2009
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: Chii-Wann Lin, Nan-Fu Chiu, Chih-Kung Lee, Kuang-Chong Wu
  • Publication number: 20070229836
    Abstract: One embodiment of the present invention is a sensor for analyzing an analyte that includes: (a) an sensing element that is adapted to interface with the analyte; (b) an organic luminescent element that is adapted to excite surface plasmon resonance on the sensing element; and (c) a detector that is adapted to detect signals from the sensing element.
    Type: Application
    Filed: April 4, 2006
    Publication date: October 4, 2007
    Applicant: National Taiwan University
    Inventors: Chii-Wann Lin, Nan-Fu Chiu, Jiun-Haw Lee, Lung-Jieh Yang, Yao-Joe Yang, Chih-Kung Lee