Abstract: Optimized chimeric antigen receptors (CARs) targeting glypican-2 (GPC2) and having a CD28 hinge region and a CD28 transmembrane domain are described. The antigen-binding domain of the disclosed CARs is derived from GPC2-specific antibody CT3 or humanized versions thereof. The optimized CARs also include an intracellular co-stimulatory domain and an intracellular signaling domain. Immune cells or induced pluripotent stem cells expressing the optimized CARs can be used to treat GPC2-positive solid tumors, such as neuroblastoma.

Abstract: A method is provided for artificially ageing a material, comprising heating the material according to a predefined temperature profile, wherein the temperature profile comprises a variable target temperature; and applying a paint bake cycle to the material.

Abstract: A method for sending system information includes: sending, by a network side, first system information to a terminal, in which the first system information includes first information of a group of second system information, and the first information includes one or a combination of: a control information aggregation level of the second system information, a number of MIMO layers of the second system information, a valid area of the second system information, valid time of the second system information, receiving condition information of the second system information, an MCS index indicating a modulation and coding scheme of a PDCCH or a PDSCH of the second system information, a modulation mode of the second system information, a subcarrier spacing for sending the second system information, and the like; and sending, by the network side, the group of second system information to the terminal based on the first information.

Abstract: A data transmission method and apparatus, and a non-transitory computer-readable storage medium are disclosed. The data transmission method may include: sending, by a first communication node, a radio frame comprising indication information to a second communication node, wherein the second communication node is associated with a third communication node, the third communication node and the first communication node perform joint transmission, and the indication information is configured to instruct a fourth communication node other than the second communication node, after receiving the radio frame, to determine whether to compete for channel access according to the indication information.

Abstract: Provided is a quad-core radio-frequency coil circuit. The quad-core radio-frequency coil circuit includes a coil module (1) and a front-end module (2). The coil module (1) is configured to receive a nuclear magnetic test signal and, according to the nuclear magnetic test signal, generate an induction signal. The front-end module (2) is connected to the coil module (1) and configured to generate the nuclear magnetic test signal and collect the induction signal.

Abstract: Provided are a transmission method and device, and a computer-readable storage medium. The transmission method includes: sending, by a first communication node, a notification frame, where the notification frame is used for instructing at least one second communication node to send a first physical layer protocol data unit (PPDU); and receiving, by the first communication node, the first PPDU sent by the at least one second communication node.

Abstract: Embodiments of the present disclosure provide a method, apparatus, electronic device and storage medium for storing data. After target data is obtained, a first data feature of the target data is extracted, the first data feature representing a data volume of the target data; the target shard number is obtained based on the first data feature, the target shard number representing the number of storage units for storing target data; a corresponding storage engine is obtained based on the target shard number, and the target data is stored in the storage engines in shards. The matched target shard number is obtained based on the first data feature of the target data, and a corresponding storage engine for storage is obtained based on the target shard number.

Abstract: This specification discloses methods, computer-readable media and apparatuses for service execution. In an example, each condition used to construct a rule and an evaluation indicator corresponding to each condition are displayed. Conditions selected by a user from candidate conditions are determined in response to a selection operation of the user. For each candidate condition, a temporary rule is determined based on the candidate condition and the conditions already selected by the user. A degree of reasonableness of each temporary rule is tested based on historical service data, and an evaluation indicator corresponding to each candidate condition is determined based on the degree of reasonableness of each temporary rule and displayed. A target rule is determined in response to a determining operation of the user. A service is executed based on the target rule and service data corresponding to an invocation instruction for invoking the target rule.

Abstract: Provided are a wireless data communication method and device, a storage medium and an electronic device. The method includes: performing an interleaving operation on first elements in a first data set and second elements in a second data set, wherein the interleaving operation includes: arranging the first elements and the second elements such that there is exchange of data between at least a part of the first elements and at least a part of the second elements, the first data set belongs to a first frequency band, the second data set belongs to a second frequency band, and there is at least one second frequency band.

Abstract: A coal and gas outburst monitoring device includes the insertion and anchoring assembly, and the pump drainage and monitoring mechanism; the insertion and anchoring assembly is vertically inserted and distributed on the sidewall of surrounding rock of coal mine roadway, and the insertion and anchoring assembly can monitor the stress change data in the sidewall of surrounding rock in real time; the pump drainage and monitoring mechanism is erected within the coal mine roadway, and the pump drainage and monitoring mechanism can cooperate with the insertion and anchoring assembly to perform the gas pump drainage monitoring for the sidewall of surrounding rock of goaf, and to obtain the gas seepage monitoring data in the surface layer and the inner layer of sidewall of surrounding rock. Thus, comparing with the database mechanism, the accurate and advanced predictions for the gas outburst can be made.

Abstract: A systems and methods for multi-node communication between wireless communication nodes and a single wireless communication device are disclosed herein. In one embodiment, the systems and methods are configured to receive, by a second wireless communication node from a first wireless communication node, a notification frame. The systems and methods can be further configured to perform joint transmission, by the second wireless communication node to a wireless communication device according to the notification frame received from the first wireless communication node. The systems and methods can also be configured to suspend, by the second wireless communication node, contention parameters of the second wireless communication node at the beginning of the transmission to the wireless communication device.

Abstract: A partial packet context builder can determine a partial packet context associated with a data packet based upon packet context associated with the data packet, the partial packet context including a plurality of partial packet context fields, where a network packet processor including an action unit, the action unit including the partial packet context builder, a systolic array of arithmetic-logical units (ALUs), and a packet context builder, the packet context including a plurality of packet context fields. The systolic array of ALUs can process the partial packet context to provide a processed partial packet context, the processed partial packet context including a plurality of processed partial packet context fields. The packet context builder can merge the processed partial packet context with the packet context to provide a processed packet context.

Abstract: Disclosed is a method of preparing glufosinate, and specifically a method of preparing glufosinate represented by formula (I) or its salt or enantiomer, or a mixture of its enantiomers in any ratio, comprising a step of hydrolyzing a compound of formula (III) to generate a compound of formula (I). Due to a distinctive reaction mechanism adopted in the method of the present disclosure, a halogenated hydrocarbon by-product in the Michaelis-Arbuzov reaction can be avoided and thus the destructive impact of the halogenated hydrocarbon by-product on ozone in the aerosphere can be prevented. Accordingly, the equipment and engineering investments required for the separation, purification, and collection of the foregoing by-product are eliminated, and the potential environmental and safety hazards brought by the foregoing by-product are also avoided.

Abstract: The present disclosure relates to clock circuits, computing chips, hash boards and data processing devices. A clock circuit comprises M stages of clock drive circuits that are connected in series, M being an integer that is no less than 2, wherein N inverters connected in series are arranged between an input port and an output port of each stage of the M stages of clock drive circuits, N being an odd number that is no less than 3. The clock circuit may provide clock signals with excellent performance.

Abstract: A chimpanzee adenovirus vector from newly discovered and isolated chimpanzee adenovirus with unique HVR sequences and a method of its construction and application thereof, with higher viral titer, and provides a method for determining its viral titer. The chimpanzee adenovirus circular vector is constructed through a shuttle plasmid, and knocks out E1 and E3 to construct a replication-defective chimpanzee adenovirus vector. The chimpanzee adenovirus vector described in this article has no preexisting antibody in the population, and the knockout of E1 and E3 is safe. At the same time, it is significantly different from human adenovirus type 5 E1 in 293 cells, which can greatly avoid recovery mutation (RCA) and make it safer. The novel coronavirus vaccine has strong stability and does not cause mutations after multiple passages, and it can induce strong humoral immunity and cellular response in mouse models.

Abstract: A coal and gas outburst monitoring device includes the insertion and anchoring assembly, and the pump drainage and monitoring mechanism; the insertion and anchoring assembly is vertically inserted and distributed on the sidewall of surrounding rock of coal mine roadway, and the insertion and anchoring assembly can monitor the stress change data in the sidewall of surrounding rock in real time; the pump drainage and monitoring mechanism is erected within the coal mine roadway, and the pump drainage and monitoring mechanism can cooperate with the insertion and anchoring assembly to perform the gas pump drainage monitoring for the sidewall of surrounding rock of goaf, and to obtain the gas seepage monitoring data in the surface layer and the inner layer of sidewall of surrounding rock. Thus, comparing with the database mechanism, the accurate and advanced predictions for the gas outburst can be made.

Abstract: A transmission method and apparatus for a wireless network, a communication node and a non-transitory computer-readable storage medium are disclosed. The transmission method for a wireless network may include: receiving a physical-layer protocol data unit (PPDU) which carries first identifier information; and keeping a locally stored network allocation vector (NAV) unchanged, or updating the locally stored NAV and ignoring the updated NAV in a process of multi-access point transmission.

Abstract: An interference suppression method and an interference suppression apparatus for air-to-ground (ATG) communications are provided. The method includes: determining first information, wherein the first information is used for one or more of the following: adjusting a maximum transmit power level of an ATG terminal; adjusting an output power value of the ATG terminal; adjusting an antenna gain of the ATG terminal; adjusting an antenna direction of the ATG terminal; determining a type of a terminal that is allowed to access an ATG base station.

Abstract: The present invention discloses a method and its application for inducing iPSC differentiation to obtain CD34+cells and NK cells. The method utilizes the three-dimensional structure of the embryoid bodies to provide a favorable differentiation microenvironment for iPSC differentiation, and can start producing a high proportion of CD34+cells on the 4th day under hypoxic induction culture conditions. Subsequently, the production of iPSC induced NK cell differentiation is significantly increased by adhering to the embryoid bodies wall or digesting and resuspension induction, And the induced differentiation of NK cells can exert a killing effect on tumor cells in a short period of time, with strong tumor killing ability, suitable for the production and clinical application of large-scale cell preparations.

Abstract: The disclosure provides a method and apparatus for extracting an avalanche signal.