Patents by Inventor Nan-Shan Chang

Nan-Shan Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating Alzheimer's disease and method for downregulating protein aggregation in brain
    Patent number: 10344065
    Abstract: A method for treating Alzheimer's disease and a method for downregulating protein aggregation in brain are disclosed, which respectively comprises: administering a zinc finger-like peptide to a subject in need thereof, wherein the zinc finger-like peptide comprises an amino acid sequence of RRSSSCK (SEQ ID NO: 1).
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: July 9, 2019
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Nan-Shan Chang, Yu-Min Kuo
  • Method for treating Alzheimer's disease and method for downregulating protein aggregation in brain
    Publication number: 20190161525
    Abstract: A method for treating Alzheimer's disease and a method for downregulating protein aggregation in brain are disclosed, which respectively comprises: administering a zinc finger-like peptide to a subject in need thereof, wherein the zinc finger-like peptide comprises an amino acid sequence of RRSSSCK (SEQ ID NO: 1).
    Type: Application
    Filed: March 6, 2018
    Publication date: May 30, 2019
    Inventors: Nan-Shan CHANG, Yu-Min KUO
  • Z cells activated by zinc finger-like protein and uses thereof in cancer treatment
    Patent number: 9546354
    Abstract: Immune cells (Z cells) activated by zinc finger-like protein that regulates apoptosis (Zfra) and uses thereof in cancer treatment.
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: January 17, 2017
    Assignee: National Cheng Kung University
    Inventors: Nan-Shan Chang, Chen-Yu Lu, Wan-Pei Su, Yu-An Chen, Wang Wan Jen
  • Modified hyaluronan and uses thereof in cancer treatment
    Patent number: 9375447
    Abstract: Uses of depolymerized hyaluronan (e.g., prepared by sonicating high molecular weight hyaluronan such as naturally-occurring hyaluronan) or anti-Hyal-2 antibody in cancer treatment. Also described herein are methods for preparing depolymerized and crosslinked hyaluronan by sonication and the hyaluronan composition thus obtained.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: June 28, 2016
    Assignee: National Cheng Kung University
    Inventors: Nan-Shan Chang, Wan-Pei Su
  • Z CELLS ACTIVATED BY ZINC FINGER-LIKE PROTEIN AND USES THEREOF IN CANCER TREATMENT
    Publication number: 20150329824
    Abstract: Immune cells (Z cells) activated by zinc finger-like protein that regulates apoptosis (Zfra) and uses thereof in cancer treatment.
    Type: Application
    Filed: May 19, 2014
    Publication date: November 19, 2015
    Applicant: National Cheng Kung University
    Inventors: Nan-Shan Chang, Chen-Yu Lu, Wan-Pei Su, Yu-An Chen, Wang Wan Jen
  • MODIFIED HYALURONAN AND USES THEREOF IN CANCER TREATMENT
    Publication number: 20140271620
    Abstract: Uses of depolymerized hyaluronan (e.g., prepared by sonicating high molecular weight hyaluronan such as naturally-occurring hyaluronan) or anti-Hyal-2 antibody in cancer treatment. Also described herein are methods for preparing depolymerized and crosslinked hyaluronan by sonication and the hyaluronan composition thus obtained.
    Type: Application
    Filed: March 14, 2013
    Publication date: September 18, 2014
    Inventors: Nan-Shan Chang, Wan-Pei Su
  • NOVEL ZINC FINGER-LIKE PEPTIDE COMPOSITIONS AS POTENT AGENTS IN CANCER PREVENTION AND TREATMENT
    Publication number: 20140135272
    Abstract: A zinc finger-like peptide for treating cancer, a pharmaceutical composition containing the zinc finger-like peptide and a method for treating cancer are disclosed. In the present invention, the zinc finger-like peptide for treating cancer comprises: at least seven amino acids, wherein the sequence of the at least seven amino acids has 85-100% similarity to a sequence represented by SEQ ID NO: 1.
    Type: Application
    Filed: July 12, 2012
    Publication date: May 15, 2014
    Inventors: Nan-Shan Chang, Ming-Hui Lee, Jean-Yang Chang, Sing-Ru Lin, Wan-Pei Su