Patents by Inventor Nan Shao
Nan Shao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250127963Abstract: An injectable hydrogel for heart failure treatment with myocardial tissue repair function and its preparation method and use are disclosed. The hydrogel is prepared by chelating alginic acid and multivalent cations. The hydrogel is loaded with an active substance for repairing cardiac injury. The active substance is recombinant humanized collagen type III. The hydrogel is administrated into the left ventricle free wall by transendocardial injection. Implanting the hydrogel in the myocardium can increase the thickness of the left ventricular wall, adjust the stress of the ventricular wall, affect the morphology of the left ventricle, and prevent or reverse left ventricular enlargement. Further, the hydrogel is loaded with a new recombinant humanized collagen material that has the function of repairing cardiac tissue injury to further improve cardiac function and promote cardiac repair.Type: ApplicationFiled: October 28, 2024Publication date: April 24, 2025Inventors: Yunbing Wang, Li Yang, Nan Shao, Xia Yang, Xingdong Zhang
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Publication number: 20240350772Abstract: An adaptive guiding device includes a hollow flexible catheter, which is pre-shaped and has a bend in a natural state. The distal part of the flexible catheter includes a distal section, the distal section includes a transition segment and a straight segment, the transition segment is bendable so as to change an orientation of the straight segment, and a bending force application point is adjacent to a connection of the transition segment with the straight segment.Type: ApplicationFiled: June 28, 2024Publication date: October 24, 2024Inventors: Nan Shao, Yang Li, Zhenping Zhuang, Jianfeng Zeng, Yijie Gan
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Publication number: 20240350767Abstract: A guide tube assembly for transcatheter treatment system has opposing distal and proximal ends. The distal section of the guide tube assembly has a curved extension including a first curved section, which is configured to have a bend angle by pre-shaping and/or bending, and a second curved section, which is located at a distal end of the first curved section and configured to have a bend angle by bending. The first curved section and the second curved section are located in different planes and provided by one or two tubes respectively which are movably inserted one in the other. The guide tube assembly is more suitable for interventional operations in complex physiological structures.Type: ApplicationFiled: June 28, 2024Publication date: October 24, 2024Inventors: Nan Shao, Yang Li, Zhenping Zhuang, Peng Zhu, Fanbo Hu, Jianfeng Zeng, Yijie Gan
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Publication number: 20240341835Abstract: A sleeve includes a main body, the main body defines a first channel passing through the main body in an axial direction, and a side wall of the main body defines at least one second channel which is communicated with the first channel. When the sleeve abuts against the ventricular tissue wall, the fluid can only flow out from the second channel in the side wall of the sleeve, which means that the needle can be advanced for treatment of the ventricular tissue.Type: ApplicationFiled: June 28, 2024Publication date: October 17, 2024Inventors: Nan Shao, Yang Li, Zhenping Zhuang, Fanbo Hu
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Publication number: 20240342388Abstract: An interventional injection device includes an operating handle, a sheath and an injection member. The operating handle includes a housing and a driving assembly. The driving assembly includes a driving knob that is rotatably connected to the housing and a driving rod that is movably inserted into the housing and threaded to the driving knob. A proximal end of the sheath is fixedly connected to the housing. The injection member is movably inserted in the sheath. The injection member includes a first channel and an injection needle connected to a distal end of the first channel in a tight seal, and a proximal end of the injection member is fixedly connected to the driving rod. The driving rod is configured to move axially by rotation of the driving knob relative to the housing.Type: ApplicationFiled: June 28, 2024Publication date: October 17, 2024Inventors: Nan Shao, Yang Li, Zhenping Zhuang, Peng Zhu
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Publication number: 20240268860Abstract: A therapeutic method for myocardial repair, includes providing a therapeutic needle, introducing the treatment needle to pierce from an epicardium into the myocardium without passing through an endocardium, and injecting therapeutant for myocardial repair through the treatment needle.Type: ApplicationFiled: March 27, 2024Publication date: August 15, 2024Applicant: Deke Medtech (Hangzhou) Inc.Inventors: Zhenjun Zi, Nan Shao, Jingjing Hu, Liwen Liu, Xiaotong Zeng, Ji Zheng
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Patent number: 12025697Abstract: The present disclosure relates to a dual-polarized phased array antenna and a dual-polarized phased array weather radar. According to the dual-polarized phased array antenna, a plurality of dual-polarized row feeds are arranged on a horizontal cylindrical support surface to form a dual-polarized antenna in a horizontal cylindrical shape. This allows two polarized signals in a horizontal direction and a vertical direction to be simultaneously received and transmitted, and ensures digital multi-beam signals with constant beam bandwidth, antenna gain, and dual polarization performance. The dual-polarized phased array weather radar provided in the present disclosure uses the formed dual-polarized microstrip patch antenna or a dual-polarized waveguide slot antenna in the horizontal cylindrical shape. This can ensure consistency of weather detected at different scan angles, and improve the accuracy of weather target 3D construction.Type: GrantFiled: March 23, 2021Date of Patent: July 2, 2024Assignee: Meteorological Observation Centre Of China Meteorological AdministrationInventors: Yuchun Gao, Chen Li, Yubao Chen, Hu Chen, Changxing Li, Jianbing Lu, Haihe Liang, Yingchun Chen, Xiaopeng Wang, Zhichao Bu, Xu Han, Nan Shao
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Patent number: 11998232Abstract: A therapeutic device, therapeutic system and therapeutic method for myocardium repair, wherein the therapeutic device comprises a treatment needle for piercing the heart to release a therapeutant. The treatment needle includes a needle body (5a), the interior of the needle body (5) has a therapeutant conveying cavity, an end of the needle body (5a) is a needle (5b) which can pierce the myocardium and guide the needle body (5a) to pass through the myocardium, and the needle (5b) has a therapeutant output port which is connected to the therapeutant conveying cavity. The therapeutic device enters into the myocardium in a minimally invasive manner to release the therapeutant to the vicinity of the lesion to improve myocardial function or activity and prevent further deterioration of the disease.Type: GrantFiled: March 29, 2019Date of Patent: June 4, 2024Assignee: DEKE MEDTECH (HANGZHOU) INC.Inventors: Zhenjun Zi, Nan Shao, Jingjing Hu, Liwen Liu, Xiaotong Zeng, Ji Zheng
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Patent number: 11860271Abstract: The present disclosure relates to spherical dual-polarization phased array weather radar. The spherical dual-polarization phased array weather radar comprises a spherical crown phased array antenna module, a digital transceiver module and a signal processing module, wherein the spherical crown phased array antenna module comprises a spherical support frame and a plurality of dual-polarization micro-strip radiation units; the dual-polarized micro-strip radiation units are tightly arranged on the spherical support frame; the spherical crown phased array antenna module is used for detecting weather; wireless transmission is carried out between the digital transceiver module and the spherical crown phased array antenna module; the digital transceiver module is used for generating a frequency modulation signal or a phase coding signal required for detecting meteorological targets and receiving an echo signal reflected by the target; and the signal processing module is connected with the digital transceiver module.Type: GrantFiled: August 16, 2021Date of Patent: January 2, 2024Assignee: Meteorological Observation Centre of China Meteorological AdministrationInventors: Yuchun Gao, Chen Li, Yubao Chen, Hu Chen, Changxing Li, Jianbing Lu, Haihe Liang, Xiaopeng Wang, Yingchun Chen, Zhichao Bu, Xu Han, Nan Shao, Jie Liu
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Publication number: 20220365208Abstract: The present disclosure relates to spherical dual-polarization phased array weather radar. The spherical dual-polarization phased array weather radar comprises a spherical crown phased array antenna module, a digital transceiver module and a signal processing module, wherein the spherical crown phased array antenna module comprises a spherical support frame and a plurality of dual-polarization micro-strip radiation units; the dual-polarized micro-strip radiation units are tightly arranged on the spherical support frame; the spherical crown phased array antenna module is used for detecting weather; wireless transmission is carried out between the digital transceiver module and the spherical crown phased array antenna module; the digital transceiver module is used for generating a frequency modulation signal or a phase coding signal required for detecting meteorological targets and receiving an echo signal reflected by the target; and the signal processing module is connected with the digital transceiver module.Type: ApplicationFiled: August 16, 2021Publication date: November 17, 2022Inventors: Yuchun GAO, Chen LI, Yubao CHEN, Hu CHEN, Changxing LI, Jianbing LU, Haihe LIANG, Xiaopeng WANG, Yingchun CHEN, Zhichao BU, Xu HAN, Nan SHAO, Jie LIU
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Publication number: 20220117591Abstract: An adsorption head includes a body. The body is a hollow housing, one side of the housing to which an adsorbed object is adsorbed is provided with an opening. The body comprises at least one adsorption chamber and at least one operation chamber therein, wherein the operation chamber and the adsorption chamber are spaced from each other and each have an opening orientated to the adsorbed object. The body has at least one adsorption passage and at least one operation passage thereon, wherein one end of the adsorption passage is communicated with the adsorption chamber, and one end of the operation passage is communicated with the operation chamber.Type: ApplicationFiled: December 27, 2021Publication date: April 21, 2022Applicant: DEKE MEDTECH (HANGZHOU) INC.Inventors: Nan SHAO, Zhiming WU, Zhenjun ZI, Jingjing HU, Mingyuan XU
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Publication number: 20210389454Abstract: The present disclosure relates to a dual-polarized phased array antenna and a dual-polarized phased array weather radar. According to the dual-polarized phased array antenna, a plurality of dual-polarized row feeds are arranged on a horizontal cylindrical support surface to form a dual-polarized antenna in a horizontal cylindrical shape. This allows two polarized signals in a horizontal direction and a vertical direction to be simultaneously received and transmitted, and ensures digital multi-beam signals with constant beam bandwidth, antenna gain, and dual polarization performance. The dual-polarized phased array weather radar provided in the present disclosure uses the formed dual-polarized microstrip patch antenna or a dual-polarized waveguide slot antenna in the horizontal cylindrical shape. This can ensure consistency of weather detected at different scan angles, and improve the accuracy of weather target 3D construction.Type: ApplicationFiled: March 23, 2021Publication date: December 16, 2021Inventors: Yuchun Gao, Chen Li, Yubao Chen, Hu Chen, Changxing Li, Jianbing Lu, Haihe Liang, Yingchun Chen, Xiaopeng Wang, Zhichao Bu, Xu Han, Nan Shao
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Patent number: 11107008Abstract: Software that uses personalized information pertaining to a user to determine how familiar (or “novel” or “surprising”) a new artifact will be to the user, by performing the following steps: (i) receiving a first dataset pertaining to a first user; (ii) building, utilizing the first dataset, an ontology of artifacts known to the first user, where the ontology includes a domain of food and a plurality of artifacts that include food recipes, and where the artifacts have corresponding characteristics that include food ingredients; (iii) calculating a prior probability distribution for each artifact of the ontology using a probabilistic familiarity algorithm; and (iv) calculating a probabilistic familiarity value for the first artifact with respect to the first user by adding the first artifact to the set of artifacts and calculating the first artifact's prior probability distribution using the probabilistic familiarity algorithm.Type: GrantFiled: November 9, 2017Date of Patent: August 31, 2021Assignee: International Business Machines CorporationInventors: Florian Pinel, Nan Shao, Kush R. Varshney, Lav R. Varshney
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Publication number: 20210121200Abstract: A therapeutic device, therapeutic system and therapeutic method for myocardium repair, wherein the therapeutic device comprises a treatment needle for piercing the heart to release a therapeutant. The treatment needle includes a needle body (5a), the interior of the needle body (5) has a therapeutant conveying cavity, an end of the needle body (5a) is a needle (5b) which can pierce the myocardium and guide the needle body (5a) to pass through the myocardium, and the needle (5b) has a therapeutant output port which is connected to the therapeutant conveying cavity. The therapeutic device enters into the myocardium in a minimally invasive manner to release the therapeutant to the vicinity of the lesion to improve myocardial function or activity and prevent further deterioration of the disease.Type: ApplicationFiled: March 29, 2019Publication date: April 29, 2021Applicant: Deke Medtech (Hangzhou) Inc.Inventors: Zhenjun ZI, Nan SHAO, Jingjing HU, Liwen LIU, Xiaotong ZENG, Ji ZHENG
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Patent number: 10768099Abstract: An in-vitro biological valve calcification evaluation method, comprising the following steps: preparing calcification evaluation solution comprising glutaraldehyde solution, saline solution, borate buffer solution, reducing calcium ingredient solution and calcium-containing plasma solution, the reducing calcium ingredient solution comprising alcohol, alkaline solution, oil and its derivatives, and buffer solution; preheating the reducing calcium ingredient solution; conducting treatment with the glutaraldehyde solution prior to reducing calcium ingredient solution; conducting treatment with the reducing calcium ingredient solution; preserving the valve samples; conducting in-vitro calcification reaction with the calcium-containing plasma solution; and detecting calcium content by atomic absorption spectrum.Type: GrantFiled: January 22, 2018Date of Patent: September 8, 2020Assignee: VENUS MEDTECH (HANGZHOU) INC.Inventors: Nan Shao, Dajun Kuang
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Publication number: 20180149585Abstract: An in-vitro biological valve calcification evaluation method, comprising the following steps: preparing calcification evaluation solution comprising glutaraldehyde solution, saline solution, borate buffer solution, reducing calcium ingredient solution and calcium-containing plasma solution, the reducing calcium ingredient solution comprising alcohol, alkaline solution, oil and its derivatives, and buffer solution; preheating the reducing calcium ingredient solution; conducting treatment with the glutaraldehyde solution prior to reducing calcium ingredient solution; conducting treatment with the reducing calcium ingredient solution; preserving the valve samples; conducting in-vitro calcification reaction with the calcium-containing plasma solution; and detecting calcium content by atomic absorption spectrum.Type: ApplicationFiled: January 22, 2018Publication date: May 31, 2018Applicant: VENUS MEDTECH (HANGZHOU), INC.Inventors: Nan SHAO, Dajun KUANG
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Publication number: 20180068230Abstract: Software that uses personalized information pertaining to a user to determine how familiar (or “novel” or “surprising”) a new artifact will be to the user, by performing the following steps: (i) receiving a first dataset pertaining to a first user; (ii) building, utilizing the first dataset, an ontology of artifacts known to the first user, where the ontology includes a domain of food and a plurality of artifacts that include food recipes, and where the artifacts have corresponding characteristics that include food ingredients; (iii) calculating a prior probability distribution for each artifact of the ontology using a probabilistic familiarity algorithm; and (iv) calculating a probabilistic familiarity value for the first artifact with respect to the first user by adding the first artifact to the set of artifacts and calculating the first artifact's prior probability distribution using the probabilistic familiarity algorithm.Type: ApplicationFiled: November 9, 2017Publication date: March 8, 2018Inventors: Florian Pinel, Nan Shao, Kush R. Varshney, Lav R. Varshney
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Patent number: 9852380Abstract: Software that uses personalized information pertaining to a user to determine how familiar (or “novel” or “surprising”) a new artifact will be to the user, by performing the following steps: (i) receiving the identity of a first user; (ii) receiving a first dataset pertaining to the first user; (iii) receiving the identity of a first artifact; and (iv) applying a probabilistic familiarity algorithm to the first dataset with respect to the first artifact to yield a probabilistic familiarity value for the first artifact with respect to the first user. The first dataset is received over a computer network, and the first dataset includes at least one piece of personalized information for the first user.Type: GrantFiled: December 31, 2014Date of Patent: December 26, 2017Assignee: International Business Machines CorporationInventors: Florian Pinel, Nan Shao, Kush R. Varshney, Lav R. Varshney
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Patent number: D962799Type: GrantFiled: December 1, 2020Date of Patent: September 6, 2022Assignee: China Meteorological Administration Meteorological Observation CenterInventors: Yuchun Gao, Chen Li, Yubao Chen, Yingchun Chen, Changxing Li, Hu Chen, Xiaopeng Wang, Jianbing Lu, Xu Han, Zhichao Bu, Haihe Liang, Nan Shao
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Patent number: D1002398Type: GrantFiled: January 8, 2021Date of Patent: October 24, 2023Assignee: China Meteorological Administration Meteorological Observation CentreInventors: Yuchun Gao, Chen Li, Yubao Chen, Yingchun Chen, Changxing Li, Hu Chen, Xiaopeng Wang, Jianbing Lu, Xu Han, Zhichao Bu, Haihe Liang, Nan Shao