Abstract: Methods for predicting at least one of the total serum bilirubin level and the hemoglobin level are proposed. The method initially uses the non-invasive measurement to detect one or more sites of the human body for acquiring the corresponding transcutaneous bilirubin and/or hemoglobin level respectively per each site. After that, the artificial intelligence is used to process the acquired results for predicting. Especially, the AI may refer to at least the detected site(s) of the human body(s) and the values of the human body related parameters. Also, the AI may be trained by process a number of measured results and comparing the predicted results with a number of invasive measurement results, such that the correlation coefficient may be approached to 1.0, at least may be about 0.9. Furthermore, neither the used non-invasive measurement nor the used AI is limited.

Abstract: A method and an optical system for evaluating the spatial distribution of the concentrations of components in tissue are disclosed. The novel detecting probe included in the optical system comprises plural optical fiber sets, each optical fiber set respectively comprises at least one source optical fiber and at least one detector optical fiber, the source optical fiber connects with the multi-wavelength light source, the source optical fiber delivers light from the multi-wavelength light source onto a tested tissue; and the angle between one optical fiber set and another optical fiber set is greater than 0° and less than and not equal to 180°. Through the optical system of the present invention, the spatial distribution of the concentrations of components such as water, hemoglobin, melanin, lipid, and collagen in the tested tissue can be derived by an equation (I) defined in the present specification.

Abstract: A method and an optical system for evaluating the spatial distribution of the concentrations of components in tissue are disclosed. The novel detecting probe included in the optical system comprises plural optical fiber sets, each optical fiber set respectively comprises at least one source optical fiber and at least one detector optical fiber, the source optical fiber connects with the multi-wavelength light source, the source optical fiber delivers light from the multi-wavelength light source onto a tested tissue; and the angle between one optical fiber set and another optical fiber set is greater than 0° and less than and not equal to 180°. Through the optical system of the present invention, the spatial distribution of the concentrations of components such as water, hemoglobin, melanin, lipid, and collagen in the tested tissue can be derived by an equation (I) defined in the present specification.