Patents by Inventor Nana Gu

Nana Gu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PD-1 antibodies and uses thereof
    Patent number: 10981991
    Abstract: The present invention provides monoclonal antibodies that specifically bind to human PD-1 with high affinity. Nucleic acid molecules encoding the antibodies of the invention, expression vectors, host cells and methods for expressing the antibodies of the invention are also provided. The PD-1 antibodies of the present invention inhibit the binding of PD-L1 to PD-1, thereby modulating immune responses in general, and those mediated by TcR and CD28, in particular. The invention also provides methods for treating various diseases, including infectious diseases and cancer using the PD-1 antibodies of the present invention.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: April 20, 2021
    Assignee: SHANGHAI ZHANGJIANG BIOTECHNOLOGY CO., LTD.
    Inventors: Nana Gu, Ke Shao
  • PD-1 ANTIBODIES AND USES THEREOF
    Publication number: 20180282412
    Abstract: The present invention provides monoclonal antibodies that specifically bind to human PD-1 with high affinity. Nucleic acid molecules encoding the antibodies of the invention, expression vectors, host cells and methods for expressing the antibodies of the invention are also provided. The PD-1 antibodies of the present invention inhibit the binding of PD-L1 to PD-1, thereby modulating immune responses in general, and those mediated by TcR and CD28, in particular. The invention also provides methods for treating various diseases, including infectious diseases and cancer using the PD-1 antibodies of the present invention.
    Type: Application
    Filed: September 29, 2016
    Publication date: October 4, 2018
    Applicant: ASIA BIOTECH PTE. LTD.
    Inventors: Nana Gu, Ke Shao