Abstract: The present invention provides antibodies that show specific reactivity to disulfide-type HMGB1. Furthermore, the present invention provides methods for specifically measuring disulfide-type HMGB1 using the antibodies, and kits or reagents for the measurement. The present invention also provides methods for measuring total HMGB1 using such an antibody and an antibody that binds to both disulfide-type HMGB1 and reduced-type HMGB1 but does not bind to des-HMGB1, and kits or reagents for the measurement.

Abstract: An information collection system is configured to collect information from information providers. The information collection system includes a first communication terminal to be owned by one of the information providers, and a server configured to perform communication with the first communication terminal. The first communication terminal includes an input interface to which speech information is input and a first transmitter configured to transmit the speech information input through the input surface. The server includes a converter configured to execute a speech recognition to convert the speech information transmitted from the first transmitter into text information, and a storage device configured to store the text information.

Abstract: An information collection system is configured to collect information from information providers. The information collection system includes a first communication terminal to be owned by one of the information providers, and a server configured to perform communication with the first communication terminal. The first communication terminal includes an input interface to which the information is input, and a first transmitter configured to transmit the input information with an ID of the information provider. The server includes a storage device configured to store the information transmitted from the first communication terminal, an evaluator configured to evaluate the information stored in the storage device, and a reward calculator configured to calculate a reward in accordance with an evaluation made by the evaluator and to add the calculated reward to a total reward to be given to the information provider identified by the ID attached to the evaluated information.

Abstract: The present invention provides antibodies that show specific reactivity to disulfide-type HMGB1. Furthermore, the present invention provides methods for specifically measuring disulfide-type HMGB1 using the antibodies, and kits or reagents for the measurement. The present invention also provides methods for measuring total HMGB1 using such an antibody and an antibody that binds to both disulfide-type HMGB1 and reduced-type HMGB1 but does not bind to des-HMGB1, and kits or reagents for the measurement.