Patents by Inventor Nancy Borson

Nancy Borson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Complexed polypeptide and adjuvant for improved vaccines
    Publication number: 20090233871
    Abstract: Immunogenic polypeptides having the capability to precipitate and focus a CpG adjuvant exhibit enhanced in vivo priming of a cytotoxic T-lymphocyte (CTL) response. Accordingly, compositions that include a bipartite immunogenic polypeptide are provided herein. The bipartite polypeptide includes a CpG-interacting amino acid sequence and a CTL-activating amino acid sequence. Also provided are methods of identifying and using a bipartite immunogenic polypeptide.
    Type: Application
    Filed: August 31, 2006
    Publication date: September 17, 2009
    Inventors: Peter J. Wettstein, Michael A. Strausbauch, Nancy Borson
  • Complexed Polypeptide and Adjuvant for Improved Vaccines
    Publication number: 20080146488
    Abstract: Attachment of the strongly immunogenic polypeptide to a more weakly immunogenic polypeptide can precipitate and focus a CpG adjuvant to increase in vivo priming of a cytotoxic T-lymphocyte (CTL) response, and thus increase the immunogenicity of the more weakly immunogenic polypeptide. Accordingly, compositions that include a bipartite immunogenic polypeptide are provided herein. The bipartite polypeptide can include a CpG-interacting amino acid sequence fused to a CTL-activating amino acid sequence that can be heterologous to the CpG-interacting amino acid sequence. Also provided are methods of identifying and using a CpG-interacting amino acid sequence and a bipartite immunogenic polypeptide.
    Type: Application
    Filed: February 4, 2005
    Publication date: June 19, 2008
    Inventors: Peter J. Wettstein, Michael A. Strausbauch, Heather A. Hardin, Nancy Borson