Patents by Inventor Nancy Braverman

Nancy Braverman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gene therapy for treating peroxisomal disorders
    Patent number: 11793887
    Abstract: Methods and compositions are provided for treatment of peroxisomal biogenesis disorders (PBDs). More particularly, recombinant adeno-associated viruses (rAAV) provided in the form of compositions are used to deliver a nucleic acid encoding human PEX1 to host cells. The rAAVs comprise a AAV capsid, and packaged therein a vector genome comprising an AAV 5? inverted terminal repeat (ITR) sequence; a promoter; a coding sequence encoding a human PEX1; and an AAV 3? ITR.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: October 24, 2023
    Assignees: The Trustees of the University of Pennsylvania, University of Southern California, The Research Institute of McGill University Health Centre
    Inventors: Nancy Braverman, Catherine Argyriou, Joseph Hacia, Jean Bennett, Junwei Sun, Ji Yun Song, Devin McDougald
  • GENE THERAPY FOR TREATING PEROXISOMAL DISORDERS
    Publication number: 20200093937
    Abstract: Methods and compositions are provided for treatment of peroxisomal biogenesis disorders (PBDs). More particularly, recombinant adeno-associated viruses (rAAV) provided in the form of compositions are used to deliver a nucleic acid encoding human PEX1 to host cells. The rAAVs comprise a AAV capsid, and packaged therein a vector genome comprising an AAV 5? inverted terminal repeat (ITR) sequence; a promoter; a coding sequence encoding a human PEX1; and an AAV 3? ITR.
    Type: Application
    Filed: May 31, 2018
    Publication date: March 26, 2020
    Inventors: Nancy Braverman, Catherine Argyriou, Joseph Hacia, Jean Bennett, Junwei Sun, Ji Yun Song, Devin McDougald