Patents by Inventor Nancy Bump

Nancy Bump has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TPL-2/COT kinase and methods of use
    Publication number: 20030219427
    Abstract: It is shown that TPL-2 is responsible for phosphorylation of p105 and its resultant proteolysis, which leads to p50 Rel translocation to the nucleus. Accordingly, the invention provides TPL-2 as a specific regulator of the activation of NF&kgr;B, and thus as a modulator of inflammatory responses in which p1O5 is involved, and as a target for the development of compounds capable of influencing NF&kgr;B activation.
    Type: Application
    Filed: February 26, 2003
    Publication date: November 27, 2003
    Inventors: Hamish J. Allen, Richard W. Dixon, Joanne S. Kamens, Dineli Wickramasinghe, Yajun Xu, Nancy Bump, Andres Salmeron, Monica P. Belich, Leland H. Johnston, Steven C. Ley, Steven J. Gamblin, Stephen J. Smerdon, Soeren Beinke, Juergen Deka