Patents by Inventor Nancy E. Gabriel

Nancy E. Gabriel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-TERMINALLY CHEMICALLY MODIFIED PROTEIN COMPOSITIONS AND METHODS
    Publication number: 20100310510
    Abstract: Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon.
    Type: Application
    Filed: December 16, 2009
    Publication date: December 9, 2010
    Applicant: AMGEN INC.
    Inventors: Olaf B. Kinstler, Nancy E. Gabriel, Christine E. Farrar, Randolph B. DePrince
  • N-terminally chemically modified protein compositions and methods
    Patent number: 7090835
    Abstract: Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: August 15, 2006
    Assignee: Amgen, Inc.
    Inventors: Nancy E. Gabriel, Christine E. Farrar
  • N-terminally chemically modified protein compositions and methods
    Publication number: 20040181035
    Abstract: Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon.
    Type: Application
    Filed: March 26, 2001
    Publication date: September 16, 2004
    Applicant: Amgen, Inc.
    Inventors: Olaf B. Kinstler, Nancy E. Gabriel, Christine E. Farrar, Randolph B. DePrince
  • N-terminally chemically modified protein compositions and methods
    Patent number: 5985265
    Abstract: Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon.
    Type: Grant
    Filed: June 20, 1997
    Date of Patent: November 16, 1999
    Assignee: Amgen Inc.
    Inventors: Olaf B. Kinstler, Nancy E. Gabriel, Christine E. Farrar, Randolph B. DePrince
  • N-terminally chemically modified protein compositions and methods
    Patent number: 5824784
    Abstract: Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon.
    Type: Grant
    Filed: October 12, 1994
    Date of Patent: October 20, 1998
    Assignee: Amgen Inc.
    Inventors: Olaf B. Kinstler, Nancy E. Gabriel, Christine E. Farrar, Randolph B. DePrince
  • Unilamellar lipid vesicles and method for their formation
    Patent number: 4921706
    Abstract: This invention relates to unilamellar lipid vesicles comprised of short-chain phospholipids and long-chain phospholipids and a method for making the vesicles. The short-chain phospholipids are comprised of fatty acids with fewer than 9 carbons atoms and the long-chain phospholipids are comprised of fatty acids with at least 12 carbon atoms.
    Type: Grant
    Filed: November 20, 1984
    Date of Patent: May 1, 1990
    Assignee: Massachusetts Institute of Technology
    Inventors: Mary P. Roberts, Nancy E. Gabriel