Patents by Inventor Nancy GAVERT

Nancy GAVERT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EX-VIVO CULTURE SYSTEM AND METHODS OF USING SAME
    Publication number: 20240228976
    Abstract: Ex-vivo culture systems are provided. Accordingly there is provided a culture system comprising a culture medium and a precision-cut tissue slice placed on a tissue culture insert, wherein the precision-cut tissue slice is maintained in a highly oxygenated atmosphere containing at least 50% oxygen and wherein said culture is rotationally agitated facilitating intermittent submersion of the tissue slice in the culture medium. Also provided are methods of culturing a tissue and methods of using the culture system for selecting a drug for the treatment of a disease.
    Type: Application
    Filed: January 24, 2024
    Publication date: July 11, 2024
    Inventors: Ravid Straussman, Nancy Gavert
  • COMBINATION THERAPY WITH A MEK INHIBITOR AND A SRC INHIBITOR FOR THE TREATMENT OF COLORECTAL CANCER
    Publication number: 20240197746
    Abstract: A method of treating colorectal cancer (CRC) is provided. The method comprises administering to a subject in need thereof a therapeutically effective amount of a Mitogen/extracellular signal-regulated kinase (MEK) inhibitor and a SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase (SRC) inhibitor, wherein cancer cells of the subject express an amount of SRC p419 above a predetermined level and do not express a KRAS G12 mutation, thereby treating the CRC.
    Type: Application
    Filed: February 28, 2024
    Publication date: June 20, 2024
    Applicants: Yeda Research and Development Co. Ltd., The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Ravid STRAUSSMAN, Nancy GAVERT, Yaara ZWANG
  • Ex-vivo culture system and methods of using same
    Patent number: 11920162
    Abstract: Ex-vivo culture systems are provided. Accordingly there is provided a culture system comprising a culture medium and a precision-cut tissue slice placed on a tissue culture insert, wherein the precision-cut tissue slice is maintained in a highly oxygenated atmosphere containing at least 50% oxygen and wherein said culture is rotationally agitated facilitating intermittent submersion of the tissue slice in the culture medium. Also provided are methods of culturing a tissue and methods of using the culture system for selecting a drug for the treatment of a disease.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: March 5, 2024
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Ravid Straussman, Nancy Gavert
  • EX-VIVO CULTURE SYSTEM AND METHODS OF USING SAME
    Publication number: 20200224171
    Abstract: Ex-vivo culture systems are provided. Accordingly there is provided a culture system comprising a culture medium and a precision-cut tissue slice placed on a tissue culture insert, wherein the precision-cut tissue slice is maintained in a highly oxygenated atmosphere containing at least 50% oxygen and wherein said culture is rotationally agitated facilitating intermittent submersion of the tissue slice in the culture medium. Also provided are methods of culturing a tissue and methods of using the culture system for selecting a drug for the treatment of a disease.
    Type: Application
    Filed: April 3, 2018
    Publication date: July 16, 2020
    Applicant: Yea Research and Development Co. Ltd.
    Inventors: Ravid STRAUSSMAN, Nancy GAVERT