Patents by Inventor Nancy H. Colburn

Nancy H. Colburn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nuclear factor kappa B pathway inhibitor composition and use of same
    Patent number: 8729053
    Abstract: An embodiment of the invention provides a pharmaceutical composition comprising a compound of formula (I) a pharmaceutically acceptable salt, prodrug, hydrate, or solvate thereof. Another embodiment of the invention provides a method of treating or preventing a condition associated with increased expression and/or activity of an NF?B pathway using same compounds. A further embodiment of the invention provides a method of diagnosing a condition in an individual using same compounds.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: May 20, 2014
    Assignee: The United States of America, as represented by the Secretary of the Department of Health and Human Services
    Inventors: Curtis J. Henrich, Moon-II Kang, Heidi R. Bokesch, Kirk R. Gustafson, Nancy H. Colburn, Matthew R. Young, James B. McMahon
  • NUCLEAR FACTOR KAPPA B PATHWAY INHIBITOR COMPOSITION AND USE OF SAME
    Publication number: 20110190240
    Abstract: An embodiment of the invention provides a pharmaceutical composition comprising a compound of formula (I)a pharmaceutically acceptable salt, prodrug, hydrate, or solvate thereof. Another embodiment of the invention provides a method of treating or preventing a condition associated with increased expression and/or activity of an NF?B pathway using same compounds. A further embodiment of the invention provides a method of diagnosing a condition in an individual using same compounds.
    Type: Application
    Filed: September 22, 2009
    Publication date: August 4, 2011
    Applicant: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES
    Inventors: Curtis J. Henrich, Moon-Il Kang, Heidi R. Bokesch, Kirk R. Gustafson, Nancy H. Colburn, Matthew R. Young, James B. McMahon
  • Dominant negative deletion mutants of C-jun and their use in the prevention and treatment of cancer
    Patent number: 6699842
    Abstract: The inhibition of AP-1 activity by dominant negative deletion mutants of c-jun is disclosed. This inhibition of AP-1 activity is shown to be associated with inhibition of tumor promoter-induced neoplastic transformation. Therefore, the invention relates to the utilization of dominant negative deletion mutants of c-jun which are inhibitory to tumor promotor-induced neoplastic transformation as therapeutic agents in the prevention and treatment of cancer in mammals.
    Type: Grant
    Filed: March 10, 1994
    Date of Patent: March 2, 2004
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Nancy H. Colburn, Zigang Dong, Powel H. Brown, Michael J. Birrer