Patents by Inventor Nancy J. Butkiewicz

Nancy J. Butkiewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric HCV/GBV-B viruses
    Publication number: 20010034019
    Abstract: This invention relates to nucleic acids encoding HCV/GBV-B constructs and chimeric, infectious HCV/GBV-B viruses that comprise a non-structural (NS) protein function of hepatitis C virus (HCV). The invention further relates to methods for using the nucleic acid constructs and chimeric, infectious viruses to screen for HCV inhibitors in cell culture models or in animal models of viral infection.
    Type: Application
    Filed: December 21, 2000
    Publication date: October 25, 2001
    Inventors: Zhi Hong, Nancy J. Butkiewicz, Weidong Zhong, Paul Ingravallo, Jacquelyn Wright-Minogue, Johnson YN Lau, Stanley M. Lemon
  • Soluble active hepatitis C virus protease
    Patent number: 5843752
    Abstract: Soluble covalent HCV NS3-NS4A complexes comprising the catalytic domain of native HICV NS3 protease fused to an HCV NS4A cofactor, wherein the cofactor has been modified to prevent cleavage by the HCV NS3 protease.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: December 1, 1998
    Assignee: Schering Corporation
    Inventors: Bimalendu Dasmahapatra, Nancy J. Butkiewicz