Patents by Inventor Nancy K. Mello

Nancy K. Mello has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vitro proton MRS detection of frequency and amount of alcohol self-administration
    Patent number: 5866427
    Abstract: In the method of the invention, in vitro proton MRS is employed to determine the measurable ethanol concentrations in ethanol-treated erythrocyte samples of occasional and heavy drinkers. An erythrocyte to plasma ethanol concentration ratio is determined based upon the MRS measured erythrocyte concentration. Erythrocyte to plasma ethanol concentration ratios are significantly greater for heavy drinkers (a subset of alcohol tolerant individuals) as compared to the ratios calculated for occasional drinkers (non-tolerant individuals) when erythrocyte ethanol concentration is determined by MRS. Thus, the method of the present invention discriminates between alcohol tolerant individuals and alcohol non-tolerant individuals based upon the magnitude of the erythrocyte to plasma ethanol concentration ratio obtained according to the methods disclosed herein.
    Type: Grant
    Filed: June 13, 1997
    Date of Patent: February 2, 1999
    Assignee: The McLean Hospital Corporation
    Inventors: Jack H. Mendelson, Nancy K. Mello, Tak-Ming Chiu
  • Method for treating pain and brain perfusion abnormalities using mixed opioid agonist-antagonists
    Patent number: 5552406
    Abstract: A method for treating pain and brain perfusion abnormalities using mixed opiate agonist/antagonists is provided.
    Type: Grant
    Filed: June 17, 1994
    Date of Patent: September 3, 1996
    Assignee: The McLean Hospital Corporation
    Inventors: Jack H. Mendelson, Nancy K. Mello
  • Treatment for cocaine abuse
    Patent number: 5075341
    Abstract: Mixed opiate agonist/antagonists, particularly buprenorphine, is provided for the treatment of cocaine dependence and concurrent cocaine and opiate abuse and dependence.
    Type: Grant
    Filed: December 1, 1989
    Date of Patent: December 24, 1991
    Assignee: The McLean Hospital Corporation
    Inventors: Jack H. Mendelson, Nancy K. Mello