Patents by Inventor Nancy Klauber Demore

Nancy Klauber Demore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targets for regulation of angiogenesis
    Patent number: 9073982
    Abstract: The present invention relates to the identification of polynucleotides and polypeptides having increased expression in tumor blood vessels. The invention further relates to the use of the identified polynucleotides and polypeptides, and inhibitors of the polynucleotides and polypeptides, in the regulation of angiogenesis and the diagnosis and treatment of angiogenesis-related diseases such as cancer.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: July 7, 2015
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Nancy Klauber DeMore, Cam Patterson, Rajendra Bhati, Bradley G. Bone
  • Novel Targets for Regulation of Angiogenesis
    Publication number: 20140294848
    Abstract: The present invention relates to the identification of polynucleotides and polypeptides having increased expression in tumor blood vessels. The invention further relates to the use of the identified polynucleotides and polypeptides, and inhibitors of the polynucleotides and polypeptides, in the regulation of angiogenesis and the diagnosis and treatment of angiogenesis-related diseases such as cancer.
    Type: Application
    Filed: March 24, 2014
    Publication date: October 2, 2014
    Applicant: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Inventors: NANCY KLAUBER DEMORE, CAM PATTERSON, RAJENDRA BHATI, BRADLEY G. BONE
  • Targets for regulation of angiogenesis
    Patent number: 8734789
    Abstract: The present invention relates to the identification of polynucleotides and polypeptides having increased expression in tumor blood vessels. The invention further relates to the use of the identified polynucleotides and polypeptides, and inhibitors of the polynucleotides and polypeptides, in the regulation of angiogenesis and the diagnosis and treatment of angiogenesis-related diseases such as cancer.
    Type: Grant
    Filed: November 12, 2010
    Date of Patent: May 27, 2014
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Nancy Klauber DeMore, Cam Patterson, Rajendra Bhati, Bradley G. Bone
  • Novel Targets for Regulation of Angiogenesis
    Publication number: 20110142820
    Abstract: The present invention relates to the identification of polynucleotides and polypeptides having increased expression in tumor blood vessels. The invention further relates to the use of the identified polynucleotides and polypeptides, and inhibitors of the polynucleotides and polypeptides, in the regulation of angiogenesis and the diagnosis and treatment of angiogenesis-related diseases such as cancer.
    Type: Application
    Filed: November 12, 2010
    Publication date: June 16, 2011
    Inventors: Nancy Klauber DeMore, Cam Patterson, Rajendra Bhati, Bradley G. Bone
  • Method of regulating the female reproductive system through angiogenesis inhibitors
    Publication number: 20020156055
    Abstract: A method of inhibiting angiogenesis in a female mammal to regulate fertility comprising administering to the female mammal an effective amount of an angiogenesis inhibiting compound. In addition, a method of inhibiting angiogenesis in a female mammal to treat a disease or condition of the reproductive tissue that is mediated by angiogenesis comprising administering to the female mammal an effective amount of an angiogenesis inhibiting compound. AGM-1470 is provided as such an angiogenesis inhibiting compound.
    Type: Application
    Filed: November 21, 2001
    Publication date: October 24, 2002
    Inventors: Robert J. D'Amato, Nancy Klauber Demore
  • Method of regulating the female reproductive system through angiogenesis inhibitors
    Patent number: 6441027
    Abstract: A method of inhibiting angiogenesis in a female mammal to regulate fertility comprising administering to the female mammal an effective amount of an angiogenesis inhibiting compound. In addition, a method of inhibiting angiogenesis in a female mammal to treat a disease or condition of the reproductive tissue that is mediated by angiogenesis comprising administering to the female mammal an effective amount of an angiogenesis inhibiting compound. AGM-1470 is provided as such an angiogenesis inhibiting compound.
    Type: Grant
    Filed: May 17, 1999
    Date of Patent: August 27, 2002
    Assignee: Children's Medical Center Corporation
    Inventors: Robert J. D'Amato, Nancy Klauber Demore
  • Method of regulating the female reproductive system through angiogenesis inhibitors
    Patent number: 6017949
    Abstract: A method of inhibiting angiogenesis in a female mammal to regulate fertility comprising administering to the female mammal an effective amount of an angiogenesis inhibiting compound. In addition, a method of inhibiting angiogenesis in a female mammal to treat a disease or condition of the reproductive tissue that is mediated by angiogenesis comprising administering to the female mammal an effective amount of an angiogenesis inhibiting compound. AGM-1470 is provided as such an angiogenesis inhibiting compound.
    Type: Grant
    Filed: August 1, 1997
    Date of Patent: January 25, 2000
    Inventors: Robert J. D'Amato, Nancy Klauber Demore