Patents by Inventor Nancy Lynn Craig

Nancy Lynn Craig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PiggyBac transposon variants and methods of use
    Patent number: 9670503
    Abstract: The present invention provides hyperactive piggyBac transposons, in particular hyperactive piggyBac transposons from Trichoplusia ni (cabbage looper moth) that transpose at a higher frequency than wildtype. The invention also features integration defective piggyBac transposons. The piggyBac transposons and transposases can be used in gene transfer systems for stably introducing nucleic acids into the DNA of a cell. The gene transfer system can be used in methods, for example, but not limited to, gene therapy, insertional mutagenesis, or gene discovery.
    Type: Grant
    Filed: September 26, 2013
    Date of Patent: June 6, 2017
    Assignee: The Johns Hopkins University
    Inventor: Nancy Lynn Craig
  • PIGGYBAC TRANSPOSON VARIANTS AND METHODS OF USE
    Publication number: 20140065124
    Abstract: The present invention provides hyperactive piggyBac transposons, in particular hyperactive piggyBac transposons from Trichoplusia ni (cabbage looper moth) that transpose at a higher frequency than wildtype. The invention also features integration defective piggyBac transposons. The piggyBac transposons and transposases can be used in gene transfer systems for stably introducing nucleic acids into the DNA of a cell. The gene transfer system can be used in methods, for example, but not limited to, gene therapy, insertional mutagenesis, or gene discovery.
    Type: Application
    Filed: September 26, 2013
    Publication date: March 6, 2014
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventor: Nancy Lynn Craig
  • PIGGYBAC TRANSPOSON VARIANTS AND METHODS OF USE
    Publication number: 20110311506
    Abstract: The present invention provides hyperactive piggyBac transposons, in particular hyperactive piggyBac transposons from Trichoplusia ni (cabbage looper moth) that transpose at a higher frequency than wildtype. The invention also features integration defective piggyBac transposons. The piggyBac transposons and transposases can be used in gene transfer systems for stably introducing nucleic acids into the DNA of a cell. The gene transfer system can be used in methods, for example, but not limited to, gene therapy, insertional mutagenesis, or gene discovery.
    Type: Application
    Filed: February 25, 2010
    Publication date: December 22, 2011
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventor: Nancy Lynn Craig