Patents by Inventor Nancy M. Franson

Nancy M. Franson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amorphous solid dispersions
    Patent number: 7713548
    Abstract: Disclosed are amorphous solid dispersion formulations comprising 7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide.
    Type: Grant
    Filed: February 12, 2008
    Date of Patent: May 11, 2010
    Assignee: sanofi-aventis U.S. LLC
    Inventors: Irwin C. Jacobs, John D. Higgins, Micael Guillot, Nancy M. Franson, William L. Rocco, Khawla Abdullah Abu-Izza
  • AMORPHOUS SOLID DISPERSIONS
    Publication number: 20080160080
    Abstract: Disclosed are amorphous solid dispersion formulations comprising 7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide.
    Type: Application
    Filed: February 12, 2008
    Publication date: July 3, 2008
    Applicant: SANOFI-AVENTIS U.S. LLC
    Inventors: Irwin C. Jacobs, John D. Higgins, Micael Guillot, Nancy M. Franson, William L. Rocco, Khawla Abdullah Abu-Izza
  • Pharmaceutical formulations containing poorly soluble drug substances
    Patent number: 6197787
    Abstract: A method for preparing pharmaceutical formulations of poorly soluble drug substances in the form of concentrated solutions for filling soft gelatin capsules and solid dispersions and suspensions for filling hard gelatin capsules and compressing into tablets is provided. Pharmaceutical formulations of poorly soluble drug substances are also disclosed. The formulations include the sodium salt of the poorly soluble drug substance, a conversion aid such as PEG, polysorbate, a sugar alcohol (e.g. mannitol or xylitol), propylene glycol or transcutol, and, in some cases an excipient, such as dicalcium phosphate dihydrate, lactose monohydrate, or microcrystalline cellulose.
    Type: Grant
    Filed: October 1, 1999
    Date of Patent: March 6, 2001
    Assignee: Sanofi-Synthelabo
    Inventors: Nancy M. Franson, Micael A. Guillot, Sharon M. Laughlin, William L. Rocco
  • Pharmaceutical formulation
    Patent number: 5760056
    Abstract: A pharmaceutical formulation comprising ##STR1## as the active ingredient, polyethylene glycol,NaOH, andwater, wherein the mole equivalents of NaOH per mole equivalent of active ingredient is at least about 1.1, is suitable for soft gelatin capsule filling.
    Type: Grant
    Filed: March 3, 1997
    Date of Patent: June 2, 1998
    Assignee: Sanofi Pharmaceuticals, Inc.
    Inventors: Sharon M. Laughlin, Nancy M. Franson
  • Milled naproxen with hydroxypropyl cellulose as a dispersion stabilizer
    Patent number: 5591456
    Abstract: Dispersible particles consisting essentially of crystalline NSAID having hydroxypropyl cellulose adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm. Pharmaceutical compositions containing the particles exhibit unexpectedly reduced gastric irritation following oral administration and/or hastened onset of action.
    Type: Grant
    Filed: February 10, 1995
    Date of Patent: January 7, 1997
    Assignee: NanoSystems L.L.C.
    Inventors: Nancy M. Franson, Donald R. Snyder