Patents by Inventor Nancy Ruffing

Nancy Ruffing has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-CCR4 antibodies and methods of use therefor
    Publication number: 20070031896
    Abstract: The present invention relates to an antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 4 (CCR4) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR4 with a ligand thereof, and to use of the antibodies and fragments in research, therapeutic, prophylactic and diagnostic methods.
    Type: Application
    Filed: June 5, 2006
    Publication date: February 8, 2007
    Inventors: Lijun Wu, Nancy Ruffing-Graham, David Andrew
  • Anti-CCR4 antibodies and methods of use therefor
    Patent number: 7138117
    Abstract: The present invention relates to an antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 4 (CCR4) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR4 with a ligand thereof, and to use of the antibodies and fragments in research, therapeutic, prophylactic and diagnostic methods.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: November 21, 2006
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Lijun Wu, Nancy Ruffing-Graham, David P. Andrew
  • ANTI-CCR4 ANTIBODIES AND METHODS OF USE THEREFOR
    Publication number: 20060246062
    Abstract: The present invention relates to an antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 4 (CCR4) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR4 with a ligand thereof, and to use of the antibodies and fragments in research, therapeutic, prophylactic and diagnostic methods.
    Type: Application
    Filed: January 18, 2002
    Publication date: November 2, 2006
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Lijun Wu, Nancy Ruffing-Graham, David Andrew
  • Anti-CCR4 antibodies and methods of use therefor
    Patent number: 6488930
    Abstract: The present invention relates to an antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 4 (CCR4) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR4 with a ligand thereof, and to use of the antibodies and fragments in research, therapeutic, prophylactic and diagnostic methods.
    Type: Grant
    Filed: January 15, 1999
    Date of Patent: December 3, 2002
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Lijun Wu, Nancy Ruffing, David Andrew