Patents by Inventor Nancy Sue Barta

Nancy Sue Barta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHOSPHORAMIDITE DERIVATIVES OF FOLIC ACID
    Publication number: 20120035362
    Abstract: The present invention provides for compounds of Formula I: wherein L and R1-R6 have any of the values defined there for in the specification. The compounds of formula I are useful as reagents to form folic acid conjugates with hydroxyl-containing compounds of interest, such as oligonucleotides and anti-cancer compounds.
    Type: Application
    Filed: August 1, 2011
    Publication date: February 9, 2012
    Applicant: Berry and Associates, Inc.
    Inventors: Nancy Sue Barta, John Cooke Hodges
  • Tetrazole and oxadiazolone substituted ?-amino acid derivatives
    Patent number: 7250433
    Abstract: This invention relates to novel tetrazole and oxadiazalone ?-amino acids derivatives of the formula wherein G is wherein R1 through R4 are defined as in the specification, pharmaceutical compositions containing them and their use for the treatment of various central nervous system and other disorders. The cyclopropyl ?-amino acids derivatives of this invention exhibit activity as alpha2delta ligands (?2? ligands). Such compounds have affinity for the ?2? subunit of a calcium channel.
    Type: Grant
    Filed: March 8, 2004
    Date of Patent: July 31, 2007
    Assignee: Warner Lambert Company LLC
    Inventors: Nancy Sue Barta, Norman Lloyd Colbry, Raymond Hudack, Jr., Kristin Knapp Lin, Jacob Bradley Schwarz, Andrew John Thorpe, David Juergen Wustrow, Zhijian Zhu
  • Amino acids with affinity for the ?-2-delta-protein
    Patent number: 7064147
    Abstract: This invention relates to certain ?-amino acids that bind to the alpha-2-delta (?2?) subunit of a calcium channel. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: June 20, 2006
    Assignee: Warner-Lambert Company
    Inventors: Nancy Sue Barta, Jacob Bradley Schwarz, Andrew John Thorpe, David Juergen Wustrow
  • Amino acids with affinity for the alpha2delta-protein
    Publication number: 20050272783
    Abstract: This invention relates to certain ?-amino acids that bind to the alpha-2-delta (?2?) subunit of a calcium channel. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric pain and other disorders.
    Type: Application
    Filed: July 1, 2005
    Publication date: December 8, 2005
    Inventors: Nancy Sue Barta, Jacob Bradley Schwarz, Andrew John Thorpe, David Juergen Wustrow
  • Method of inhibiting amyloid protein aggregation and imaging amyloid deposits using aminoindane derivatives
    Patent number: 6949575
    Abstract: The present invention provides compounds of Formula (I) and a method of treating Alzheimer's disease using a compound of Formula (I), wherein: R1 and R2 include alkyl and phenylalkyl; R3 is hydrogen or alkyl; and R4 and R5 include alkyl, alkoxy, carboxyl, alkoxycarbonyl, and nitro. Also provided is a method of inhibiting the aggregation of amyloid proteins using a compound of Formula (I) and a method of imaging amyloid deposits using compounds of Formula (I).
    Type: Grant
    Filed: April 25, 2001
    Date of Patent: September 27, 2005
    Assignee: Pfizer Inc.
    Inventors: Nancy Sue Barta, Christopher Franklin Bigge
  • Method of inhibiting amyloid protein aggregation and imaging amyloid deposits using aminoindane derivatives
    Publication number: 20030220382
    Abstract: The present invention provides compounds of Formula (I) and a method of treating Alzheimer's disease using a compound of Formula (I), wherein: R1 and R2 include alkyl and phenylalkyl; R3 is hydrogen or alkyl; and R4 and R5 include alkyl, alkoxy, carboxyl, alkoxycarbonyl, and nitro. Also provided is a method of inhibiting the aggregation of amyloid proteins using a compound of Formula (I) and a method of imaging amyloid deposits using compounds of Formula (I).
    Type: Application
    Filed: November 4, 2002
    Publication date: November 27, 2003
    Inventors: Nancy Sue Barta, Christopher Franklin Bigge
  • Amino acids with affinity for the alpha-2-delta-protein
    Publication number: 20030195251
    Abstract: This invention relates to certain &bgr;-amino acids that bind to the alpha-2-delta (&agr;2&dgr;) subunit of a calcium channel. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders.
    Type: Application
    Filed: March 27, 2003
    Publication date: October 16, 2003
    Inventors: Nancy Sue Barta, Jacob Bradley Schwarz, Andrew John Thorpe, David Juergen Wustrow