Patents by Inventor Nandini Nagraj

Nandini Nagraj has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10989709
    Abstract: A method of recovering a target from a sample is provided. The method of recovering the target follows different steps. The steps include providing a binding element, wherein the binding elements are immobilized on a solid support, adding the sample comprising the target to the binding element to form a binding element-target complex; washing the binding element-target complex; and eluting the target from the binding element-target complex. The system for reversible detection of target in a range from 2 to 1,000,000 bind/release cycles is also provided.
    Type: Grant
    Filed: March 22, 2017
    Date of Patent: April 27, 2021
    Assignee: CYTIVA SWEDEN AB
    Inventors: Radislav Alexandrovich Potyrailo, Andrew David Pris, Nandini Nagraj, Anthony John Murray
  • Patent number: 10359419
    Abstract: A method of recovering a target from a sample is provided. The method comprises the adding a substrate coupled binding element to the sample comprising the target to form a substrate coupled binding element-target complex; precipitating the complex by changing one or more environmental conditions of the substrate and recovering the target and the substrate coupled binding-element under mild conditions.
    Type: Grant
    Filed: October 2, 2013
    Date of Patent: July 23, 2019
    Assignee: General Electric Company
    Inventors: Anthony John Murray, Radislav Alexandrovich Potyrailo, Andrew David Pris, Nandini Nagraj
  • Patent number: 10244778
    Abstract: A method for monitoring cooking in an oven appliance includes drawing cooking vapors or gases from a cooking chamber to a fluid analysis assembly of the oven appliance during a gas or vapor analysis cooking cycle, determining a cooking status of the food item within the cooking chamber with the controller of the oven appliance based upon a response pattern of a plurality of fluid sensors of the fluid analysis assembly to the cooking vapors or gases during the gas or vapor analysis cooking cycle, and activating an alert with the controller of the oven appliance when the cooking status of the food item within the cooking chamber is a particular cooking status.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: April 2, 2019
    Assignee: Haier US Appliance Solutions, Inc.
    Inventors: James Lee Armstrong, Stanton Earl Weaver, Jr., Sabrina Marie Hannah, Nandini Nagraj, Manuel Alfredo Palacios
  • Patent number: 10001415
    Abstract: The subject matter of the present disclosure generally relates to a sensor assembly having a first component configured to melt when a temperature of the sensor assembly reaches a first value below a minimum value of a predetermined temperature range, a second component configured to melt when the temperature of the sensor assembly reaches a second value above a maximum value of the predetermined temperature range, and a third component configured to monitor a volume of fluid disposed in a vessel when the temperature of the sensor assembly is within the predetermined temperature range.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: June 19, 2018
    Assignee: General Electric Company
    Inventors: Nandini Nagraj, Timothy Mark Sivavec, Yongjae Lee, Daniel Paik
  • Patent number: 9828599
    Abstract: Methods for selecting a binding-element are provided. The method comprised of different steps. A first mixture is formed using at least one target molecule and a plurality of oligomers, followed by incubating the first mixture to form a second mixture comprising at least one target-bound oligomer and at least one target-unbound oligomer. Then a first accelerator is added to cleave the target-unbound oligomer and the target-bound oligomer is separated from the target molecule. This is followed by addition of a second accelerator for ligation, and a third accelerator for amplification followed by sequencing and post sequence analysis to select the binding-element.
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: November 28, 2017
    Assignee: General Electric Company
    Inventors: Nandini Nagraj, Radislav Alexandrovich Potyrailo, Andrew David Pris, John Richard Nelson
  • Publication number: 20170267716
    Abstract: Provided herein are aptamer-polymer conjugates which are responsive to environmental stimuli and are useful in selective purification of untagged target polypeptides.
    Type: Application
    Filed: March 16, 2016
    Publication date: September 21, 2017
    Inventors: Anthony John Murray, Andrew David Pris, Erik Leeming Kvam, Nandini Nagraj, Eugene Pauling Boden, Ernest William Kovacs, Louisa Ruth Carr, Rui Chen, Tiberiu Mircea Siclovan, Kelly Scott Chichak
  • Publication number: 20170191992
    Abstract: A method of recovering a target from a sample is provided. The method of recovering the target follows different steps. The steps include providing a binding element, wherein the binding elements are immobilized on a solid support, adding the sample comprising the target to the binding element to form a binding element-target complex; washing the binding element-target complex; and eluting the target from the binding element-target complex. The system for reversible detection of target in a range from 2 to 1,000,000 bind/release cycles is also provided.
    Type: Application
    Filed: March 22, 2017
    Publication date: July 6, 2017
    Inventors: Radislav Alexandrovich Potyrailo, Andrew David Pris, Nandini Nagraj, Anthony John Murray
  • Patent number: 9678030
    Abstract: A sensor for detecting gaseous agents has a transducer, which includes an electrical resonant circuit that forms an antenna. The sensor further includes a sensing material that is disposed on at least a portion of the transducer. The sensing material is configured to simultaneously exhibit a capacitance response and a resistance response in the presence of a gaseous agent. The sensor may be reversible, battery free, and may require no electrical contact with a sensor reader.
    Type: Grant
    Filed: December 30, 2014
    Date of Patent: June 13, 2017
    Assignee: General Electricity Company
    Inventors: Radislav Alexandrovich Potyrailo, Zhexiong Tang, Brandon Bartling, Nandini Nagraj, Vadim Bromberg
  • Publication number: 20170130967
    Abstract: The present subject matter provides an oven appliance with a fluid analysis assembly fluidly mounted to a duct. The fluid analysis assembly includes a casing and a sensor array. A fluid inlet of the casing extends between the duct and a dilution chamber of the casing. An ambient inlet of the casing is contiguous with ambient air about the casing and the dilution chamber. The sensor array includes a plurality of fluid sensors positioned at the dilution chamber of the casing.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 11, 2017
    Inventors: Stanton Earl Weaver, JR., Gary Dwayne Mandrusiak, Nandini Nagraj
  • Publication number: 20170130968
    Abstract: A method for monitoring cooking in an oven appliance includes drawing cooking vapors or gases from a cooking chamber to a fluid analysis assembly and exposing a plurality of fluid sensors of the fluid analysis assembly to the cooking vapors or gases. The method also includes establishing a response pattern of the plurality of fluid sensors with a machine or statistical learning model(s) and determining a cooking status of the food item within the cooking chamber based upon the response pattern of the plurality of fluid sensors.
    Type: Application
    Filed: November 10, 2015
    Publication date: May 11, 2017
    Inventors: Nandini Nagraj, Stanton Earl Weaver, JR., Zhexiong Tang, Manuel Alfredo Palacios, Igor Tokarev, Matthew Vaughan Schulmerich
  • Publication number: 20170127700
    Abstract: A method for monitoring cooking in an oven appliance includes drawing cooking vapors or gases from a cooking chamber to a fluid analysis assembly of the oven appliance during a gas or vapor analysis cooking cycle, determining a cooking status of the food item within the cooking chamber with the controller of the oven appliance based upon a response pattern of a plurality of fluid sensors of the fluid analysis assembly to the cooking vapors or gases during the gas or vapor analysis cooking cycle, and activating an alert with the controller of the oven appliance when the cooking status of the food item within the cooking chamber is a particular cooking status.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 11, 2017
    Inventors: James Lee Armstrong, Stanton Earl Weaver, JR., Sabrina Marie Hannah, Nandini Nagraj, Manuel Alfredo Palacios
  • Patent number: 9638653
    Abstract: Methods and sensors for selective fluid sensing are provided. Each sensor includes a resonant inductor-capacitor-resistor (LCR) sensor that is coated with a sensing material. In order to collect data, an impedance spectrum is acquired over a relatively narrow frequency range, such as the resonant frequency range of the LCR circuit. A multivariate signature may be calculated from the acquired spectrum to discern the presence of certain fluids and/or fluid mixtures. The presence of fluids is detected by measuring the changes in dielectric, dimensional, resistance, charge transfer, and other changes in the properties of the materials employed by observing the changes in the resonant electronic properties of the circuit. By using a mathematical procedure, such as principal components analysis (PCA) and others, multiple fluids and mixtures can be detected in the presence of one another, even in a high humidity environment or an environment wherein one or more fluids has a substantially higher concentration (e.g.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: May 2, 2017
    Assignee: General Electricity Company
    Inventors: Radislav Alexandrovich Potyrailo, Cheryl Margaret Surman, Andrew Arthur Paul Burns, Nandini Nagraj
  • Publication number: 20170043095
    Abstract: The subject matter of the present disclosure generally relates to a sensor assembly having a first component configured to melt when a temperature of the sensor assembly reaches a first value below a minimum value of a predetermined temperature range, a second component configured to melt when the temperature of the sensor assembly reaches a second value above a maximum value of the predetermined temperature range, and a third component configured to monitor a volume of fluid disposed in a vessel when the temperature of the sensor assembly is within the predetermined temperature range.
    Type: Application
    Filed: August 11, 2015
    Publication date: February 16, 2017
    Inventors: Nandini Nagraj, Timothy Mark Sivavec, Yongjae Lee, Daniel Paik
  • Patent number: 9494541
    Abstract: Methods and sensors for selective fluid sensing are provided. A gas dosimeter includes a housing configured with an opening to admit an analyte. The gas dosimeter also includes a multivariate sensor disposed in the housing. The sensor is configured to determine a concentration of the analyte over time. In addition, the multivariate sensor includes an irreversible sensing material. Electrical properties of the irreversible sensing material are configured to change irreversibly upon exposure to the analyte.
    Type: Grant
    Filed: July 5, 2012
    Date of Patent: November 15, 2016
    Assignee: General Electricity Company
    Inventors: Radislav Alexandrovich Potyrailo, Hubert Tunchiao Lam, Zhexiong Tang, Nandini Nagraj
  • Publication number: 20160223484
    Abstract: Methods and sensors for selective fluid sensing are provided. Each sensor includes a resonant inductor-capacitor-resistor (LCR) sensor that is coated with a sensing material. In order to collect data, an impedance spectrum is acquired over a relatively narrow frequency range, such as the resonant frequency range of the LCR circuit. A multivariate signature may be calculated from the acquired spectrum to discern the presence of certain fluids and/or fluid mixtures. The presence of fluids is detected by measuring the changes in dielectric, dimensional, resistance, charge transfer, and other changes in the properties of the materials employed by observing the changes in the resonant electronic properties of the circuit. By using a mathematical procedure, such as principal components analysis (PCA) and others, multiple fluids and mixtures can be detected in the presence of one another, even in a high humidity environment or an environment wherein one or more fluids has a substantially higher concentration (e.g.
    Type: Application
    Filed: May 12, 2015
    Publication date: August 4, 2016
    Inventors: Radislav Alexandrovich Potyrailo, Cheryl Margaret Surman, Andrew Arthur Paul Burns, Nandini Nagraj
  • Publication number: 20160187280
    Abstract: A sensor for detecting gaseous agents has a transducer, which includes an electrical resonant circuit that forms an antenna. The sensor further includes a sensing material that is disposed on at least a portion of the transducer. The sensing material is configured to simultaneously exhibit a capacitance response and a resistance response in the presence of a gaseous agent. The sensor may be reversible, battery free, and may require no electrical contact with a sensor reader.
    Type: Application
    Filed: December 30, 2014
    Publication date: June 30, 2016
    Inventors: Radislav Alexandrovich Potyralio, Zhexiong Tang, Brandon Bartling, Nandini Nagraj, Vadim Bromberg
  • Publication number: 20160033140
    Abstract: An oven appliance with a sensor for sensing gases in the cooking chamber is provided. One or more features and methods are provided for detecting the gas levels in the cooking chamber to determine if the cooking chamber is clean or unclean. Features for initiating and terminating an oven cleaning cycle are also provided.
    Type: Application
    Filed: July 30, 2014
    Publication date: February 4, 2016
    Inventors: Stanton Earl Weaver, JR., Nandini Nagraj, William Guy Morris, Todd-Michael Striker, Zhexiong Tang, Manuel Alfredo Palacios
  • Patent number: 9037418
    Abstract: Methods and sensors for selective fluid sensing are provided. Each sensor includes a resonant inductor-capacitor-resistor (LCR) sensor that is coated with a sensing material. In order to collect data, an impedance spectrum is acquired over a relatively narrow frequency range, such as the resonant frequency range of the LCR circuit. A multivariate signature may be calculated from the acquired spectrum to discern the presence of certain fluids and/or fluid mixtures. The presence of fluids is detected by measuring the changes in dielectric, dimensional, resistance, charge transfer, and other changes in the properties of the materials employed by observing the changes in the resonant electronic properties of the circuit. By using a mathematical procedure, such as principal components analysis (PCA) and others, multiple fluids and mixtures can be detected in the presence of one another, even in a high humidity environment or an environment wherein one or more fluids has a substantially higher concentration (e.g.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: May 19, 2015
    Assignee: General Electric Company
    Inventors: Radislav Alexandrovich Potyrailo, Cheryl Margaret Surman, Andrew Arthur Paul Burns, Nandini Nagraj
  • Publication number: 20150093820
    Abstract: A method of recovering a target from a sample is provided. The method comprises the adding a substrate coupled binding element to the sample comprising the target to form a substrate coupled binding element-target complex; precipitating the complex by changing one or more environmental conditions of the substrate and recovering the target and the substrate coupled binding-element under mild conditions.
    Type: Application
    Filed: October 2, 2013
    Publication date: April 2, 2015
    Applicant: General Electric Company
    Inventors: Anthony John Murray, Radislav Alexandrovich Potyrailo, Andrew David Pris, Nandini Nagraj
  • Publication number: 20150093839
    Abstract: A method of recovering a target from a sample is provided. The method of recovering the target follows different steps. The steps include providing a binding element, wherein the binding elements are immobilized on a solid support, adding the sample comprising the target to the binding element to form a binding element-target complex; washing the binding element-target complex; and eluting the target from the binding element-target complex. The system for reversible detection of target in a range from 2 to 1,000,000 bind/release cycles is also provided.
    Type: Application
    Filed: October 2, 2013
    Publication date: April 2, 2015
    Applicant: General Electric Company
    Inventors: Radislav Alexandrovich Potyrailo, Andrew David Pris, Nandini Nagraj, Anthony John Murray