Patents by Inventor Nandini Nataraj

Nandini Nataraj has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusion proteins and method of expression thereof
    Patent number: 8975041
    Abstract: The present invention relates to novel Prolipase-Bovine trypsinogen (PLBTR) fusion proteins, the genes encoding them, and the production and uses thereof. More specifically, the present invention relates to methods of producing in optimal quantities PLBTR fusion proteins which comprise a heterologous polypeptide which is normally susceptible to autocatalytic activity. More particularly, the present invention relates to fusion proteins which comprise an heterologous polypeptide, such as a serine protease, fused to a lipase signal sequence, which can be expressed by recombinant host cells in desired amounts. The present invention further relates to polynucleotides encoding such fusion proteins, to expression vectors for expression of such fusion proteins, to host cells transformed with such polynucleotides/vectors, and to methods of generating such fusion proteins.
    Type: Grant
    Filed: October 26, 2009
    Date of Patent: March 10, 2015
    Assignee: Biocon Limited
    Inventors: Nagaraj Govindappa, Nandini Nataraj, Sanjay Tiwari, Partha Hazra, Mukesh Babuappa Patale, Gokul Jothiraman, Kedarnath Sastry
  • NOVEL FUSION PROTEINS AND METHOD OF EXPRESSION THEREOF
    Publication number: 20120231520
    Abstract: The present invention relates to novel Prolipase-Bovine trypsinogen (PLBTR) fusion proteins, the genes encoding them, and the production and uses thereof. More specifically, the present invention relates to methods of producing in optimal quantities PLBTR fusion proteins which comprise a heterologous polypeptide which is normally susceptible to autocatalytic activity. More particularly, the present invention relates to fusion proteins which comprise an heterologous polypeptide, such as a serine protease, fused to a lipase signal sequence, which can be expressed by recombinant host cells in desired amounts. The present invention further relates to polynucleotides encoding such fusion proteins, to expression vectors for expression of such fusion proteins, to host cells transformed with such polynucleotides/vectors, and to methods of generating such fusion proteins.
    Type: Application
    Filed: October 26, 2009
    Publication date: September 13, 2012
    Applicant: BIOCON LIMITED
    Inventors: Nagaraj Govindappa, Nandini Nataraj, Sanjay Tiwari, Partha Hazra, Mukesh Babuappa Patale, Gokul Jothiraman, Kedarnath Sastry