Patents by Inventor Nandu Bhise

Nandu Bhise has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparation of darunavir and darunavir ethanolate of fine particle size
    Patent number: 9062067
    Abstract: The present invention provides a novel process for preparation of darunavir that involves reduction of [(1S,2R)-3-[[(4-nitrophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic acid (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester, of formula (5). The present invention also provides darunavir ethanolate of particle size wherein d0.9 is less than 130 ?m, d0.5 is less than 30 ?m, d0.1 is less than 10 ?m and process for its preparation.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: June 23, 2015
    Assignee: LUPIN LIMITED
    Inventors: Vijay Ahire, Sachin Sasane, Amol Deshmukh, Krishnat Kumbhar, Akshat Bhatnagar, Devendra Verma, Rajesh Vyas, Girij Pal Singh, Nandu Bhise
  • Process for preparation of darunavir and darunavir ethanolate of fine particle size
    Patent number: 9062065
    Abstract: The present invention provides a novel process for preparation of darunavir that involves reduction of [(1S,2R)-3-[[(4-nitrophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic acid (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester, of formula (5). The present invention also provides darunavir ethanolate of particle size wherein d0.9 is less than 130 ?m, d0.5 is less than 30 ?m, d0.1 is less than 10 ?m and process for its preparation.
    Type: Grant
    Filed: November 1, 2010
    Date of Patent: June 23, 2015
    Assignee: LUPIN LIMITED
    Inventors: Vijay Ahire, Sachin Sasane, Amol Deshmukh, Krishnat Kumbhar, Akshat Bhatnagar, Devendra Verma, Rajesh Vyas, Girij Pal Singh, Nandu Bhise
  • NOVEL PROCESS FOR PREPARATION OF DARUNAVIR AND DARUNAVIR ETHANOLATE OF FINE PARTICLE SIZE
    Publication number: 20140066638
    Abstract: The present invention provides a novel process for preparation of darunavir that involves reduction of [(1S,2R)-3-[[(4-nitrophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic acid (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester, of formula (5). The present invention also provides darunavir ethanolate of particle size wherein d0.9 is less than 130 ?m, d0.5 is less than 30 ?m, d0.1 is less than 10 ?m and process for its preparation.
    Type: Application
    Filed: November 8, 2013
    Publication date: March 6, 2014
    Applicant: Lupin Limited
    Inventors: Vijay AHIRE, Sachin SASANE, Amol DESHMUKH, Krishnat KUMBHAR, Akshat BHATNAGAR, Devendra VERMA, Rajesh VYAS, Girij Pal SINGH, Nandu BHISE
  • NOVEL PROCESS FOR PREPARATION OF DARUNAVIR AND DARUNAVIR ETHANOLATE OF FINE PARTICLE SIZE
    Publication number: 20120237770
    Abstract: The present invention provides a novel process for preparation of darunavir that involves reduction of [(1S,2R)-3-[[(4-nitrophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy -1-(phenylmethyl)propyl]carbamic acid (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester, of formula (5). The present invention also provides darunavir ethanolate of particle size wherein d0.9 is less than 130 ?m, d0.5 is less than 30 ?m, d0.1 is less than 10 ?m and process for its preparation.
    Type: Application
    Filed: November 1, 2010
    Publication date: September 20, 2012
    Applicant: Lupin Limited
    Inventors: Vijay Ahire, Sachin Sasane, Amol Deshmukh, Krishnat Kumbhar, Akshat Bhatnagar, Devendra Verma, Rajesh Vyas, Girij Pal Singh, Nandu Bhise