Patents by Inventor Nanguneri Nirmala

Nanguneri Nirmala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200048686
    Abstract: The present disclosure relates to development and performance of screening methods capable of efficiently identifying candidate lead compounds that bind regulatory RNA oligonucleotides in a sequence-specific manner and exert a biological effect upon such regulatory molecules. Candidate lead compounds possessing RNA binding sequence specificity and targeted biological activity are described, as are approaches for merging structural, NMR-derived data with biological reporter assay results. Compound validation approaches capable of identifying the site(s) of action of such compounds within targeted RNA oligonucleotides are also provided.
    Type: Application
    Filed: April 26, 2018
    Publication date: February 13, 2020
    Applicant: THE RNA MEDICINES COMPANY, INC.
    Inventors: Dalia Cohen, Michelle Markus, Jun Jiang, Michel Guiraldelli, Justin Boyd, Branko Radetich, Nanguneri Nirmala, Johan Pontin
  • Publication number: 20070275391
    Abstract: The present invention relates to in particular immune modulatory polypeptides and polynucleotides, recombinant materials and methods for their production. Such polypeptides and polynucleotides are of interest in relation to methods of treatment of diseases whereby immune responses initiated by dendritic cells (DC), monocytes or lymphocytes, play a causal or contributory role.
    Type: Application
    Filed: September 29, 2006
    Publication date: November 29, 2007
    Inventors: Gung-Wei Chirn, Uwe Dengler, Frank Kolbinger, Quicheng Ma, Nanguneri Nirmala, Klaus Seuwen, Gudrun Werner
  • Publication number: 20050107589
    Abstract: The present invention relates to in particular immune modulatory polypeptides and polynucleotides, recombinant materials and methods for their production. Such polypeptides and polynucleotides are of interest in relation to methods of treatment of diseases whereby immune responses initiated by dendritic cells (DC), monocytes or lymphocytes, play a causal or contributory role.
    Type: Application
    Filed: December 16, 2002
    Publication date: May 19, 2005
    Inventors: Gung-Wei Chirn, Uwe Dengler, Frank Kolbinger, Qicheng Ma, Nanguneri Nirmala, Klaus Seuwen, Gudrun Werner