Patents by Inventor Nanping Zhong

Nanping Zhong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the enantiomoeric separation of optical active amlodipine
    Patent number: 7678921
    Abstract: The present invention relates to the preparation of the (S)-(?)-amlodipine and (R)-(+)-amlodipine by means of enantiomeric separation of racemic amlodipine mixture, in which, L- or D-tartaric acid is used as resolution agent, and organic solvent containing 2-butanone is used as solvent. The 2-butanone used in the present invention has the advantage of low boiling point, low toxicity, litter pollution, and the method is suitable for large-scaled production.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: March 16, 2010
    Assignee: Shijiazhuang Pharmaceutical Group Ouyl Pharma. Co., Ltd.
    Inventors: Nanping Zhong, Xianfeng Zhao, Hui Ma, Yujie Chen
  • Method for the enantiomoeric separation of optical active amlodipine
    Publication number: 20070093661
    Abstract: The present invention relates to the preparation of the (S)-(?)-amlodipine and (R)-(+)-amlodipine by means of enantiomoeric separation of racemic amlodipine mixture, in which, L- or D-tartaric acid is used as resolution agent, and organic solvent containing 2-butone is used as solvent. The 2-butone used in the present invention has the advantage of low boiling point, low toxicity, litter pollution, and the method is suitable for large-scaled production.
    Type: Application
    Filed: December 3, 2004
    Publication date: April 26, 2007
    Applicant: SHIJIAZHUANG PHARMACEUTICAL GROUP OUYL PHAMA CO., LTD
    Inventors: Nanping Zhong, Xianfeng Zhao, Hui Ma, Yujle Chen