Patents by Inventor Naofumi Takehara

Naofumi Takehara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIGHLY FUNCTIONALIZED STEM CELL/PROGENITOR CELL BY APE1 GENE TRANSFECTION
    Publication number: 20140030239
    Abstract: The present invention relates to: a highly functionalized stem cell/progenitor cell (e.g., endothelial progenitor cell or mesenchymal stem cell) improved in its functions such as angiogenesis by increased expression of Ape1; and revascularization medicine using the cell.
    Type: Application
    Filed: August 9, 2011
    Publication date: January 30, 2014
    Inventors: Junichi Kawabe, Atsushi Yamauchi, Naofumi Takehara, Naoyuki Hasebe
  • Preparation for treating heart disease used in cell therapy
    Patent number: 8414924
    Abstract: An object of the present invention is to establish a cell transplantation method which can markedly improve the survival of grafted pluripotent stem cells and the efficiency of cardiomyocyte regeneration in cell therapy using pluripotent stem cells derived from heart tissue and can treat heart disease further effectively. Specifically, according to the present invention, enhancement in the survival of grafted pluripotent stem cells and significant improvement in the efficiency of cardiomyocyte regeneration are achieved by using, in combination, pluripotent stem cells derived from heart tissue and a hydrogel containing a basic fibroblast growth factor (bFGF) in cell therapy for heart disease.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: April 9, 2013
    Assignee: Kyoto University
    Inventors: Hidemasa Oh, Naofumi Takehara, Hiroaki Matsubara, Yasuhiko Tabata
  • PREPARATION FOR TREATING HEART DISEASE USED IN CELL THERAPY
    Publication number: 20100303909
    Abstract: An object of the present invention is to establish a cell transplantation method which can markedly improve the survival of grafted pluripotent stem cells and the efficiency of cardiomyocyte regeneration in cell therapy using pluripotent stem cells derived from heart tissue and can treat heart disease further effectively. Specifically, according to the present invention, enhancement in the survival of grafted pluripotent stem cells and significant improvement in the efficiency of cardiomyocyte regeneration are achieved by using, in combination, pluripotent stem cells derived from heart tissue and a hydrogel containing a basic fibroblast growth factor (bFGF) in cell therapy for heart disease.
    Type: Application
    Filed: October 9, 2008
    Publication date: December 2, 2010
    Applicant: KYOTO UNIVERSITY
    Inventors: Hidemasa Oh, Naofumi Takehara, Hiroaki Matsubara, Yasuhiko Tabata