Patents by Inventor Naohiro Yabuta

Naohiro Yabuta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Humanized antibody against human tissue factor (TF) and process of production of the humanized antibody
    Patent number: 6677436
    Abstract: The present invention relates to a human/mouse chimeric antibody that includes the variable region of a mouse monoclonal antibody against human tissue factor (TF) and the constant region of a human antibody. The humanized antibody contains light and heavy chain complementarity determining regions of a mouse monoclonal antibody against human TF which have been grafted onto a human antibody. The present invention also provides a therapeutic agent for disseminated intravascular coagulation (DIC) syndrome, which includes a humanized antibody against human TF as an active ingredient.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: January 13, 2004
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Koh Sato, Hideki Adachi, Naohiro Yabuta